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Related papers: A Hele-Shaw limit without monotonicity

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We consider a model of congestion dynamics with chemotaxis, where the density of cells follows the chemical signal it generates, while observing an incompressibility constraint. We show that when the chemical diffuses slowly and attracts…

Analysis of PDEs · Mathematics 2022-04-27 Inwon Kim , Antoine Mellet , Yijing Wu

This paper investigates the incompressible limit of a system modelling the growth of two cells population. The model describes the dynamics of cell densities, driven by pressure exclusion and cell proliferation. It has been shown that…

Analysis of PDEs · Mathematics 2019-01-08 P. Degond , S. Hecht , N. Vauchelet

The porous medium type reaction-diffusion equation and the Hele-Shaw problem are two free boundary problems linked through the incompressible (Hele-Shaw) limit. We investigate and compare the sharp power concavities of the pressures on…

Analysis of PDEs · Mathematics 2025-09-11 Qingyou He

We study a singular limit of the classical parabolic-elliptic Patlak-Keller-Segel (PKS) model for chemotaxis with non linear diffusion. The main result is the $\Gamma$ convergence of the corresponding energy functional toward the perimeter…

Analysis of PDEs · Mathematics 2023-05-09 Antoine Mellet

We present a robust computational framework for Hele-Shaw tumor growth with necrotic cores, a problem identified as the incompressible limit of the Porous Media Equation. Simulating this system presents a fundamental challenge: while the…

Numerical Analysis · Mathematics 2026-02-16 Yu Feng , Shuo Ling , Wenjun Ying , Zhennan Zhou

Nowadays a vast literature is available on the Hele-Shaw or incompressible limit for nonlinear degenerate diffusion equations. This problem has attracted a lot of attention due to its applications to tissue growth and crowd motion modelling…

Analysis of PDEs · Mathematics 2025-10-29 Noemi David , Alpár R. Mészáros , Filippo Santambrogio

The link between compressible models of tissue growth and the Hele-Shaw free boundary problem of fluid mechanics has recently attracted a lot of attention. In most of these models, only repulsive forces and advection terms are taken into…

Analysis of PDEs · Mathematics 2023-05-11 Charles Elbar , Benoît Perthame , Andrea Poiatti , Jakub Skrzeczkowski

We investigate the large time behavior of an agent based model describing tumor growth. The microscopic model combines short-range repulsion and cell division. As the number of cells increases exponentially in time, the microscopic model is…

Soft Condensed Matter · Physics 2017-01-04 Sebastien Motsch , Diane Peurichard

Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…

Analysis of PDEs · Mathematics 2023-11-01 Xu'an Dou , Chengfeng Shen , Zhennan Zhou

In this paper, we study the tumor growth equation along with various models for the nutrient component, including the \emph{in vitro} model and the \emph{in vivo} model. At the cell density level, the spatial availability of the tumor…

Analysis of PDEs · Mathematics 2018-02-05 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

We consider a model of congestion dynamics with chemotaxis: The density of cells follows a chemical signal it generates, while subject to an incompressibility constraint. The incompressibility constraint results in the formation of patches,…

Analysis of PDEs · Mathematics 2023-01-18 Inwon Kim , Antoine Mellet , Yijing Wu

In this paper, we characterize a degenerate PDE as the gradient flow in the space of nonnegative measures endowed with an optimal transport-growth metric. The PDE of concern, of Hele-Shaw type, was introduced by Perthame et. al. as a…

Analysis of PDEs · Mathematics 2017-12-19 Lénaïc Chizat , Simone Di Marino

We study the incompressible limit of the porous medium equation with a reaction term that is non-monotone with respect to the pressure variable. More specifically we consider reaction terms that are either bistable or monostable. We show…

Analysis of PDEs · Mathematics 2022-08-22 Inwon Kim , Antoine Mellet

We analyze a system of cross-diffusion equations that models the growth of an avascular-tumor spheroid. The model incorporates two nonlinear diffusion effects, degeneracy type and super diffusion. We prove the global existence of weak…

Analysis of PDEs · Mathematics 2022-10-14 Samiha Belmor

We revisit the problem of proving the incompressible limit for the compressible porous media equation with Newtonian drift and growth. The question is motivated by models of living tissues development including chemotaxis. We extend the…

Analysis of PDEs · Mathematics 2023-12-29 Qingyou He , Hai-Liang Li , Benoît Perthame

We study a Hele-Shaw problem with a mushy region obtained as a Mesa type limit of one phase Stefan problems in exterior domains. We study the convergence, determine some of the qualitative properties and regularity of the unique limiting…

Analysis of PDEs · Mathematics 2007-05-23 I. A. Blank , M. K. Korten , C. N. Moore

We investigate the tumor boundary instability induced by nutrient consumption and supply based on a Hele-Shaw model derived from taking the incompressible limit of a cell density model. We analyze the boundary stability/instability in two…

Analysis of PDEs · Mathematics 2023-05-17 Yu Feng , Min Tang , Xiaoqian Xu , Zhennan Zhou

We study the linear stability of the displacement of three Stokes fluids with constant viscosity in a porous medium when the middle fluid is contained in a bounded region. We use the Hele-Shaw model. The eigenfunctions of the stability…

Analysis of PDEs · Mathematics 2022-11-08 Gelu Paşa

We study the dynamics of compressible fluids in rotating heterogeneous porous media. The fluid flow is of {F}orchheimer-type and is subject to a mixed mass and volumetric flux boundary condition. The governing equations are reduced to a…

Analysis of PDEs · Mathematics 2026-05-27 Emine Celik , Luan Hoang , Thinh Kieu

In this work we study a tissue growth model with applications to tumour growth. The model is based on that of Perthame, Quir\'os, and V\'azquez proposed in 2014 but incorporates the advective effects caused, for instance, by the presence of…

Analysis of PDEs · Mathematics 2021-03-04 Noemi David , Markus Schmidtchen