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Experimental designs for a generalized linear model (GLM) often depend on the specification of the model, including the link function, the predictors, and unknown parameters, such as the regression coefficients. To deal with uncertainties…

Methodology · Statistics 2026-05-12 Yiou Li , Lulu Kang , Xinwei Deng

We present strong mixed-integer programming (MIP) formulations for high-dimensional piecewise linear functions that correspond to trained neural networks. These formulations can be used for a number of important tasks, such as verifying…

Optimization and Control · Mathematics 2020-01-23 Ross Anderson , Joey Huchette , Will Ma , Christian Tjandraatmadja , Juan Pablo Vielma

Planning the maintenance of nuclear power plants is a complex optimization problem, involving a joint optimization of maintenance dates, fuel constraints and power production decisions. This paper investigates Mixed Integer Linear…

Artificial Intelligence · Computer Science 2020-09-08 Nicolas Dupin , El-Ghazali Talbi

This paper analyzes the integration of artificial intelligence (AI) with mixed integer linear programming (MILP) to address complex optimization challenges in air transportation with explainability. The study aims to validate the use of…

We give an explicit geometric way to build mixed-integer programming (MIP) formulations for unions of polyhedra. The construction is simply described in terms of spanning hyperplanes in an r-dimensional linear space. The resulting MIP…

Optimization and Control · Mathematics 2019-10-11 Joey Huchette , Juan Pablo Vielma

We propose a framework for the stability verification of Mixed-Integer Linear Programming (MILP) representable control policies. This framework compares a fixed candidate policy, which admits an efficient parameterization and can be…

Systems and Control · Electrical Eng. & Systems 2023-06-02 Roland Schwan , Colin N. Jones , Daniel Kuhn

A large number of real-world optimization problems can be formulated as Mixed Integer Linear Programs (MILP). MILP solvers expose numerous configuration parameters to control their internal algorithms. Solutions, and their associated costs…

Machine Learning · Computer Science 2023-07-04 Abdelrahman Hosny , Sherief Reda

Software for mixed-integer linear programming can return incorrect results for a number of reasons, one being the use of inexact floating-point arithmetic. Even solvers that employ exact arithmetic may suffer from programming or algorithmic…

Optimization and Control · Mathematics 2019-01-03 Kevin K. H. Cheung , Ambros Gleixner , Daniel E. Steffy

Mixed Binary Quadratic Programs (MBQPs) are an important and complex set of problems in combinatorial optimization. As solving large-scale combinatorial optimization problems is challenging, primal heuristics have been developed to quickly…

Machine Learning · Computer Science 2026-04-28 Weimin Huang , Natalie M. Isenberg , Ján Drgoňa , Draguna L Vrabie , Bistra Dilkina

A novel two-phase molecule inference framework, mol-infer, has recently been developed to infer chemical graphs with prescribed abstract structures and desired property values through mixed integer linear programming (MILP) under the…

Quantitative Methods · Quantitative Biology 2026-05-29 Jianshen Zhu , Raveena Rai , Taiyo Sohkawa , Naveed Ahmed Azam , Kazuya Haraguchi , Liang Zhao , Tatsuya Akutsu

Mixed integer linear programming (MILP) has seen a sharp rise in use for engineering optimization applications in recent years. Even for initially non-linear problems, it is often the method of choice. Then, the non-linear functions have to…

Optimization and Control · Mathematics 2023-09-20 Felix Birkelbach , David Huber , René Hofmann

Transfer learning from large-scale pre-trained models has become essential for many computer vision tasks. Recent studies have shown that datasets like ImageNet are weakly labeled since images with multiple object classes present are…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Sai Rajeswar , Pau Rodriguez , Soumye Singhal , David Vazquez , Aaron Courville

A standard tool for modelling real-world optimisation problems is mixed-integer programming (MIP). However, for many of these problems, information about the relationships between variables is either incomplete or highly complex, making it…

Optimization and Control · Mathematics 2024-05-24 Mark Turner , Antonia Chmiela , Thorsten Koch , Michael Winkler

Integer Linear Programming (ILP) has a broad range of applications in various areas of artificial intelligence. Yet in spite of recent advances, we still lack a thorough understanding of which structural restrictions make ILP tractable.…

Discrete Mathematics · Computer Science 2020-03-17 Pavel Dvořák , Eduard Eiben , Robert Ganian , Dušan Knop , Sebastian Ordyniak

Contrastive Language-Image Pretraining (CLIP) has achieved remarkable success, leading to rapid advancements in multimodal studies. However, CLIP faces a notable challenge in terms of inefficient data utilization. It relies on a single…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Yu Zhang , Qi Zhang , Zixuan Gong , Yiwei Shi , Yepeng Liu , Duoqian Miao , Yang Liu , Ke Liu , Kun Yi , Wei Fan , Liang Hu , Changwei Wang

It is well known that selecting a good Mixed Integer Programming (MIP) formulation is crucial for an effective solution with state-of-the art solvers. While best practices and guidelines for constructing good formulations abound, there is…

Optimization and Control · Mathematics 2017-05-23 Juan Pablo Vielma

With the growing complexity of computational and experimental facilities, many scientific researchers are turning to machine learning (ML) techniques to analyze large scale ensemble data. With complexities such as multi-component workflows,…

Linear programming (LP) relaxations are widely employed in exact solution methods for multilinear programs (MLP). One example is the family of Recursive McCormick Linearization (RML) strategies, where bilinear products are substituted for…

Optimization and Control · Mathematics 2022-07-20 Arvind U Raghunathan , Carlos Cardonha , David Bergman , Carlos J Nohra

A key feature of inductive logic programming (ILP) is its ability to learn first-order programs, which are intrinsically more expressive than propositional programs. In this paper, we introduce techniques to learn higher-order programs.…

Machine Learning · Computer Science 2019-07-26 Andrew Cropper , Rolf Morel , Stephen H. Muggleton

When implementing model predictive control (MPC) for hybrid systems with a linear or a quadratic performance measure, a mixed-integer linear program (MILP) or a mixed-integer quadratic program (MIQP) needs to be solved, respectively, at…

Systems and Control · Electrical Eng. & Systems 2025-04-11 Shamisa Shoja , Daniel Arnström , Daniel Axehill