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The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

Machine Learning · Computer Science 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Recurrent Neural Networks (RNNs) have been a prominent concept within artificial intelligence. They are inspired by Biological Neural Networks (BNNs) and provide an intuitive and abstract representation of how BNNs work. Derived from the…

Neural and Evolutionary Computing · Computer Science 2017-03-09 Stefano Nichele , Andreas Molund

The interpretability of machine learning models has been an essential area of research for the safe deployment of machine learning systems. One particular approach is to attribute model decisions to high-level concepts that humans can…

Machine Learning · Computer Science 2022-09-14 Varsha Pendyala , Jihye Choi

Concept Activation Vectors (CAVs) provide a powerful approach for interpreting deep neural networks by quantifying their sensitivity to human-defined concepts. However, when computed independently at different layers, CAVs often exhibit…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhenghao He , Sanchit Sinha , Guangzhi Xiong , Aidong Zhang

Recurrent neural networks (RNNs) have been used extensively and with increasing success to model various types of sequential data. Much of this progress has been achieved through devising recurrent units and architectures with the…

Machine Learning · Statistics 2017-03-06 Yacine Jernite , Edouard Grave , Armand Joulin , Tomas Mikolov

Learning temporal patterns from multivariate longitudinal data is challenging especially in cases when data is sporadic, as often seen in, e.g., healthcare applications where the data can suffer from irregularity and asynchronicity as the…

Machine Learning · Computer Science 2021-04-09 Mostafa Mehdipour Ghazi , Lauge Sørensen , Sébastien Ourselin , Mads Nielsen

Circuits of biological neurons, such as in the functional parts of the brain can be modeled as networks of coupled oscillators. Inspired by the ability of these systems to express a rich set of outputs while keeping (gradients of) state…

Machine Learning · Computer Science 2021-03-16 T. Konstantin Rusch , Siddhartha Mishra

Recurrent Neural Networks (RNNs) have achieved remarkable performance on a range of tasks. A key step to further empowering RNN-based approaches is improving their explainability and interpretability. In this work we present MEME: a model…

Machine Learning · Computer Science 2021-04-15 Dmitry Kazhdan , Botty Dimanov , Mateja Jamnik , Pietro Liò

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

Sequence labeling is a widely used method for named entity recognition and information extraction from unstructured natural language data. In clinical domain one major application of sequence labeling involves extraction of medical entities…

Computation and Language · Computer Science 2016-08-03 Abhyuday Jagannatha , Hong Yu

The study of deep recurrent neural networks (RNNs) and, in particular, of deep Reservoir Computing (RC) is gaining an increasing research attention in the neural networks community. The recently introduced Deep Echo State Network (DeepESN)…

Machine Learning · Computer Science 2020-09-28 Claudio Gallicchio , Alessio Micheli

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…

Machine Learning · Computer Science 2024-05-08 Jiayuan Chen , Changchang Yin , Yuanlong Wang , Ping Zhang

Electronic Health Records (EHRs) are typically stored as time-stamped encounter records. Observing temporal relationship between medical records is an integral part of interpreting the information. Hence, statistical analysis of EHRs…

Applications · Statistics 2020-07-29 Anne Woods , Craig Meyer , Brian Sauer , Beth Cohen

In recent years, we have witnessed an increased interest in temporal modeling of patient records from large scale Electronic Health Records (EHR). While simpler RNN models have been used for such problems, memory networks, which in other…

Machine Learning · Computer Science 2020-07-15 Prithwish Chakraborty , Fei Wang , Jianying Hu , Daby Sow

Over the long history of machine learning, which dates back several decades, recurrent neural networks (RNNs) have been used mainly for sequential data and time series and generally with 1D information. Even in some rare studies on 2D…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Nguyen Huu Phong , Bernardete Ribeiro

Electroencephalography (EEG) is a widely used tool for diagnosing brain disorders due to its high temporal resolution, non-invasive nature, and affordability. Manual analysis of EEG is labor-intensive and requires expertise, making…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Salim Rukhsar , Anil Kumar Tiwari

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

Predicting diagnoses from Electronic Health Records (EHRs) is an important medical application of multi-label learning. We propose a convolutional residual model for multi-label classification from doctor notes in EHR data. A given patient…

Machine Learning · Statistics 2018-08-10 Xinyuan Zhang , Ricardo Henao , Zhe Gan , Yitong Li , Lawrence Carin

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

Machine Learning · Computer Science 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

Clinical medical data, especially in the intensive care unit (ICU), consist of multivariate time series of observations. For each patient visit (or episode), sensor data and lab test results are recorded in the patient's Electronic Health…

Machine Learning · Computer Science 2017-03-23 Zachary C. Lipton , David C. Kale , Charles Elkan , Randall Wetzel