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With the evolution of single-cell RNA sequencing techniques into a standard approach in genomics, it has become possible to conduct cohort-level causal inferences based on single-cell-level measurements. However, the individual gene…

Methodology · Statistics 2025-04-23 Jin-Hong Du , Zhenghao Zeng , Edward H. Kennedy , Larry Wasserman , Kathryn Roeder

We introduce stochastic variational inference for Gaussian process models. This enables the application of Gaussian process (GP) models to data sets containing millions of data points. We show how GPs can be vari- ationally decomposed to…

Machine Learning · Computer Science 2013-09-27 James Hensman , Nicolo Fusi , Neil D. Lawrence

There is a wide range of applications where the local extrema of a function are the key quantity of interest. However, there is surprisingly little work on methods to infer local extrema with uncertainty quantification in the presence of…

Methodology · Statistics 2023-09-28 Meng Li , Zejian Liu , Cheng-Han Yu , Marina Vannucci

Linear systems occur throughout engineering and the sciences, most notably as differential equations. In many cases the forcing function for the system is unknown, and interest lies in using noisy observations of the system to infer the…

The paper considers a Cox process where the stochastic intensity function for the Poisson data model is itself a non-homogeneous Poisson process. We show that it is possible to obtain the marginal data process, namely a non-homogeneous…

Methodology · Statistics 2023-04-17 Shuying Wang , Stephen G. Walker

This work considers estimation and forecasting in a multivariate, possibly high-dimensional count time series model constructed from a transformation of a latent Gaussian dynamic factor series. The estimation of the latent model parameters…

Methodology · Statistics 2025-04-07 Younghoon Kim , Marie-Christine Düker , Zachary F. Fisher , Vladas Pipiras

We observe $n$ inhomogeneous Poisson processes with covariates and aim at estimating their intensities. We assume that the intensity of each Poisson process is of the form $s (\cdot, x)$ where $x$ is the covariate and where $s$ is an…

Statistics Theory · Mathematics 2013-06-14 Mathieu Sart

Many probabilistic models introduce strong dependencies between variables using a latent multivariate Gaussian distribution or a Gaussian process. We present a new Markov chain Monte Carlo algorithm for performing inference in models with…

Computation · Statistics 2010-03-22 Iain Murray , Ryan Prescott Adams , David J. C. MacKay

It is well known that the dependence structure for jointly Gaussian variables can be fully captured using correlations, and that the conditional dependence structure in the same way can be described using partial correlations. The partial…

Methodology · Statistics 2019-09-24 Håkon Otneim , Dag Tjøstheim

Sparse variational Gaussian process (SVGP) methods are a common choice for non-conjugate Gaussian process inference because of their computational benefits. In this paper, we improve their computational efficiency by using a dual…

Machine Learning · Computer Science 2022-01-20 Vincent Adam , Paul E. Chang , Mohammad Emtiyaz Khan , Arno Solin

Given a sample from a discretely observed multidimensional compound Poisson process, we study the problem of nonparametric estimation of its jump size density $r_0$ and intensity $\lambda_0$. We take a nonparametric Bayesian approach to the…

Statistics Theory · Mathematics 2015-06-08 Shota Gugushvili , Frank van der Meulen , Peter Spreij

We consider evidence integration from potentially dependent observation processes under varying spatio-temporal sampling resolutions and noise levels. We develop a multi-resolution multi-task (MRGP) framework while allowing for both…

Machine Learning · Statistics 2019-11-06 Oliver Hamelijnck , Theodoros Damoulas , Kangrui Wang , Mark Girolami

Gaussian processes (GPs) are a powerful tool for probabilistic inference over functions. They have been applied to both regression and non-linear dimensionality reduction, and offer desirable properties such as uncertainty estimates,…

Machine Learning · Statistics 2014-10-01 Yarin Gal , Mark van der Wilk , Carl E. Rasmussen

We introduce new estimators of the inhomogeneous $K$-function and the pair correlation function of a spatial point process as well as the cross $K$-function and the cross pair correlation function of a bivariate spatial point process under…

Methodology · Statistics 2020-10-06 Thomas Shaw , Jesper Møller , Rasmus Waagepetersen

We present a novel approach for the analysis of multivariate case-control georeferenced data using Bayesian inference in the context of disease mapping, where the spatial distribution of different types of cancers is analyzed. Extending…

In this paper, we present a novel methodology to perform Bayesian inference for Cox processes in which the intensity function is driven by a diffusion process. The novelty lies in the fact that no discretization error is involved, despite…

Methodology · Statistics 2023-06-06 Flavio B. Gonçalves , Krzysztof G. Łatuszyński , Gareth O. Roberts

Some scenarios require the computation of a predictive distribution of a new value evaluated on an objective function conditioned on previous observations. We are interested on using a model that makes valid assumptions on the objective…

Machine Learning · Computer Science 2021-01-21 Lucia Asencio-Martín , Eduardo C. Garrido-Merchán

We show that by using intuitive and accessible molecular features it is possible to predict the temperature-dependent second virial coefficient of organic and inorganic compounds using Gaussian process regression. In particular, we built a…

Chemical Physics · Physics 2021-02-24 Miruna T. Cretu , Jesús Pérez-Ríos

Gaussian states are an essential building block for various applications in quantum optics and quantum information science, yet the precise relation between their second- and third-order correlation functions remains not fully explored. We…

Quantum Physics · Physics 2025-12-22 Philip Heinzel , René Sondenheimer

Falsification is the basis for testing existing hypotheses, and a great danger is posed when results incorrectly reject our prior notions (false positives). Though nonparametric and nonlinear exploratory methods of uncovering coupling…

Methodology · Statistics 2022-06-08 Ameer Ghouse , Gaetano Valenza
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