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Currently, Coronavirus disease (COVID-19), one of the most infectious diseases in the 21st century, is diagnosed using RT-PCR testing, CT scans and/or Chest X-Ray (CXR) images. CT (Computed Tomography) scanners and RT-PCR testing are not…

For fast development of COVID-19, it is only feasible to use drugs (off label use) or approved natural products that are already registered or been assessed for safety in previous human trials. These agents can be quickly assessed in…

Biomolecules · Quantitative Biology 2020-12-01 Sakshi Piplani , Puneet Singh , David A. Winkler , Nikolai Petrovsky

The emergence of the novel COVID-19 pandemic has had a significant impact on global healthcare and the economy over the past few months. The virus's rapid widespread has led to a proliferation in biomedical research addressing the pandemic…

Artificial Intelligence · Computer Science 2020-07-21 Chongyan Chen , Islam Akef Ebeid , Yi Bu , Ying Ding

The COVID-19 (coronavirus) is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was first identified in mid-December 2019 in the Hubei province of Wuhan, China and by now has spread…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Aditya Saxena , Shamsheer Pal Singh

The outbreak of COVID-19 caused millions of deaths worldwide, and the number of total infections is still rising. It is necessary to identify some potentially effective drugs that can be used to prevent the development of severe symptoms or…

Molecular Networks · Quantitative Biology 2022-09-07 Fan Hu , Jiaxin Jiang , Peng Yin

Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and…

Biomolecules · Quantitative Biology 2023-09-26 Srilekha Mamidala

The world is still struggling in controlling and containing the spread of the COVID-19 pandemic caused by the SARS-CoV-2 virus. The medical conditions associated with SARS-CoV-2 infections have resulted in a surge in the number of patients…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Hossein Aboutalebi , Maya Pavlova , Mohammad Javad Shafiee , Ali Sabri , Amer Alaref , Alexander Wong

The mathematical modeling of infectious diseases is a fundamental research field for the planning of strategies to contain outbreaks. The models associated with this field of study usually have exponential prior assumptions in the number of…

Signal Processing · Electrical Eng. & Systems 2020-07-02 Jhony H. Giraldo , Thierry Bouwmans

This technical report proposes the use of a deep convolutional neural network as a preliminary diagnostic method in the analysis of chest computed tomography images from patients with symptoms of Severe Acute Respiratory Syndrome (SARS) and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Victor Felipe Reis-Silva

Until now, Coronavirus SARS-CoV-2 has caused more than 850,000 deaths and infected more than 27 million individuals in over 120 countries. Besides principal polymerase chain reaction (PCR) tests, automatically identifying positive samples…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Duy M. H. Nguyen , Duy M. Nguyen , Huong Vu , Binh T. Nguyen , Fabrizio Nunnari , Daniel Sonntag

Adverse Drug Reaction (ADR) is a significant public health concern world-wide. Numerous graph-based methods have been applied to biomedical graphs for predicting ADRs in pre-marketing phases. ADR detection in post-market surveillance is no…

Machine Learning · Computer Science 2020-04-02 Heeyoung Kwak , Minwoo Lee , Seunghyun Yoon , Jooyoung Chang , Sangmin Park , Kyomin Jung

The world has witnessed unprecedented human and economic loss from the COVID-19 disease, caused by the novel coronavirus SARS-CoV-2. Extensive research is being conducted across the globe to identify therapeutic agents against the…

Biomolecules · Quantitative Biology 2020-04-09 Rohit Batra , Henry Chan , Ganesh Kamath , Rampi Ramprasad , Mathew J. Cherukara , Subramanian Sankaranarayanan

The COVID-19 pandemic continues to rage on, with multiple waves causing substantial harm to health and economies around the world. Motivated by the use of CT imaging at clinical institutes around the world as an effective complementary…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Hayden Gunraj , Ali Sabri , David Koff , Alexander Wong

Background: Identifying new indications for approved drugs is a complex and time-consuming process that requires extensive knowledge of pharmacology, clinical data, and advanced computational methods. Recently, deep learning (DL) methods…

Machine Learning · Computer Science 2025-11-13 Shuting Jin , Yi Jiang , Yimin Liu , Tengfei Ma , Dongsheng Cao , Leyi Wei , Xiangrong Liu , Xiangxiang Zeng

Coronavirus Disease 2019 (COVID-19) is a rapidly emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to the rapid human-to-human transmission of SARS-CoV-2, many healthcare systems…

Machine Learning · Computer Science 2020-12-01 Patrick Schwab , August DuMont Schütte , Benedikt Dietz , Stefan Bauer

The reliable and rapid identification of the COVID-19 has become crucial to prevent the rapid spread of the disease, ease lockdown restrictions and reduce pressure on public health infrastructures. Recently, several methods and techniques…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Tawsifur Rahman , Alex Akinbi , Muhammad E. H. Chowdhury , Tarik A. Rashid , Abdulkadir Şengür , Amith Khandakar , Khandaker Reajul Islam , Aras M. Ismael

The world is currently experiencing an ongoing pandemic of an infectious disease named coronavirus disease 2019 (i.e., COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Computed Tomography (CT)…

Image and Video Processing · Electrical Eng. & Systems 2021-12-10 Qinghao Ye , Yuan Gao , Weiping Ding , Zhangming Niu , Chengjia Wang , Yinghui Jiang , Minhao Wang , Evandro Fei Fang , Wade Menpes-Smith , Jun Xia , Guang Yang

Global coronavirus disease pandemic (COVID-19) caused by newly identified SARS- CoV-2 coronavirus continues to claim the lives of thousands of people worldwide. The unavailability of specific medications to treat COVID-19 has led to drug…

Quantitative Methods · Quantitative Biology 2020-06-12 Romeo Cozac , Nazim Medzhidov , Shinya Yuki

The 2019 novel coronavirus disease (COVID-19), with a starting point in China, has spread rapidly among people living in other countries, and is approaching approximately 34,986,502 cases worldwide according to the statistics of European…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Ali Narin , Ceren Kaya , Ziynet Pamuk

The novel coronavirus disease, named COVID-19, emerged in China in December 2019, and has rapidly spread around the world. It is clearly urgent to fight COVID-19 at global scale. The development of methods for identifying drug uses based on…

Quantitative Methods · Quantitative Biology 2021-10-06 Lu Han , G. C. Shan , B. F. Chu , H. Y. Wang , Z. J. Wang , S. Q. Gao , W. X. Zhou