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The large-scale properties of chemical reaction systems, such as the metabolism, can be studied with graph-based methods. To do this, one needs to reduce the information -- lists of chemical reactions -- available in databases. Even for the…

Molecular Networks · Quantitative Biology 2009-09-25 Petter Holme

Graphs are widespread data structures used to model a wide variety of problems. The sheer amount of data to be processed has prompted the creation of a myriad of systems that help us cope with massive scale graphs. The pressure to deliver…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-10-09 Luis M. Vaquero , Felix Cuadrado , Matei Ripeanu

We consider global dynamics of reaction systems as introduced by Ehrenfeucht and Rozenberg. The dynamics is represented by a directed graph, the so-called transition graph, and two reaction systems are considered equivalent if their…

Combinatorics · Mathematics 2018-08-07 Daniela Genova , Hendrik Jan Hoogeboom , Nataša Jonoska

Graphs are widely used as a popular representation of the network structure of connected data. Graph data can be found in a broad spectrum of application domains such as social systems, ecosystems, biological networks, knowledge graphs, and…

Machine Learning · Computer Science 2021-05-04 Feng Xia , Ke Sun , Shuo Yu , Abdul Aziz , Liangtian Wan , Shirui Pan , Huan Liu

One approach to studying the system-wide organization of biochemistry is to use statistical graph theory. Even in such a heavily simplified method, which disregards most of the dynamic aspects of biochemistry, one is faced with fundamental…

Molecular Networks · Quantitative Biology 2010-08-17 Petter Holme , Mikael Huss

We present a systematic investigation using graph neural networks (GNNs) to model organic chemical reactions. To do so, we prepared a dataset collection of four ubiquitous reactions from the organic chemistry literature. We evaluate seven…

Machine Learning · Computer Science 2020-07-10 Serim Ryou , Michael R. Maser , Alexander Y. Cui , Travis J. DeLano , Yisong Yue , Sarah E. Reisman

Graph processing has become an important part of various areas of computing, including machine learning, medical applications, social network analysis, computational sciences, and others. A growing amount of the associated graph processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-01 Maciej Besta , Marc Fischer , Vasiliki Kalavri , Michael Kapralov , Torsten Hoefler

Acting on time-critical events by processing ever growing social media, news or cyber data streams is a major technical challenge. Many of these data sources can be modeled as multi-relational graphs. Mining and searching for subgraph…

Databases · Computer Science 2013-06-12 Sutanay Choudhury , Lawrence Holder , George Chin , Abhik Ray , Sherman Beus , John Feo

Graph transformation formalisms have proven to be suitable tools for the modelling of chemical reactions. They are well established in theoretical studies and increasingly also in practical applications in chemistry. The latter is made…

Discrete Mathematics · Computer Science 2022-08-29 Jakob L. Andersen , Rolf Fagerberg , Juri Kolčák , Christophe V. F. P. Laurent , Daniel Merkle , Nikolai Nøjgaard

Graph burning is a round-based game or process that discretely models the spread of influence throughout a network. We introduce a generalization of graph burning which applies to hypergraphs, as well as a variant called ''lazy'' hypergraph…

Combinatorics · Mathematics 2025-08-12 Andrea C. Burgess , Caleb W. Jones , David A. Pike

Graphs are ubiquitous and ever-present data structures that have a wide range of applications involving social networks, knowledge bases and biological interactions. The evolution of a graph in such scenarios can yield important insights…

Data Structures and Algorithms · Computer Science 2019-02-15 Lefteris Zervakis , Vinay Setty , Christos Tryfonopoulos , Katja Hose

Interacting systems are prevalent in nature. It is challenging to accurately predict the dynamics of the system if its constituent components are analyzed independently. We develop a graph-based model that unveils the systemic interactions…

Machine Learning · Computer Science 2024-10-31 Giangiacomo Mercatali , Andre Freitas , Jie Chen

Graph neural networks are widely used to learn global representations of graphs, which are then used for regression or classification tasks. Typically, the graphs in such data sets are connected, i.e. each training sample consists of a…

Computational Engineering, Finance, and Science · Computer Science 2022-11-01 Chen Shao , Zhou Chen , Pascal Friederich

Dynamical systems with complex behaviours, e.g. immune system cells interacting with a pathogen, are commonly modelled by splitting the behaviour into different regimes, or modes, each with simpler dynamics, and then learning the switching…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Yongtuo Liu , Sara Magliacane , Miltiadis Kofinas , Efstratios Gavves

Graphs are fundamental data structures which concisely capture the relational structure in many important real-world domains, such as knowledge graphs, physical and social interactions, language, and chemistry. Here we introduce a powerful…

Machine Learning · Computer Science 2018-03-12 Yujia Li , Oriol Vinyals , Chris Dyer , Razvan Pascanu , Peter Battaglia

A graph is a structure composed of a set of vertices (i.e.nodes, dots) connected to one another by a set of edges (i.e.links, lines). The concept of a graph has been around since the late 19$^\text{th}$ century, however, only in recent…

Data Structures and Algorithms · Computer Science 2010-12-24 Marko A. Rodriguez , Peter Neubauer

We extend previous work on injectivity in chemical reaction networks to general interaction networks. Matrix- and graph-theoretic conditions for injectivity of these systems are presented. A particular signed, directed, labelled, bipartite…

Dynamical Systems · Mathematics 2009-10-15 Murad Banaji , Gheorghe Craciun

Graphs have a superior ability to represent relational data, like chemical compounds, proteins, and social networks. Hence, graph-level learning, which takes a set of graphs as input, has been applied to many tasks including comparison,…

Machine Learning · Computer Science 2023-05-26 Zhenyu Yang , Ge Zhang , Jia Wu , Jian Yang , Quan Z. Sheng , Shan Xue , Chuan Zhou , Charu Aggarwal , Hao Peng , Wenbin Hu , Edwin Hancock , Pietro Liò

Modern energy systems in vehicles and built infrastructure are governed by high-dimensional dynamics spanning multiple physical domains (e.g., electrical, thermal, mechanical) and timescales. This tutorial paper presents a graph-based…

Graphs are commonly used to characterise interactions between objects of interest. Because they are based on a straightforward formalism, they are used in many scientific fields from computer science to historical sciences. In this paper,…

Machine Learning · Statistics 2015-06-24 Pierre Latouche , Fabrice Rossi
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