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Background: Clinical prediction models are increasingly used to inform healthcare decisions, but determining the minimum sample size for their development remains a critical and unresolved challenge. Inadequate sample sizes can lead to…

Machine Learning · Computer Science 2026-03-02 Diana Shamsutdinova , Felix Zimmer , Oyebayo Ridwan Olaniran , Sarah Markham , Daniel Stahl , Gordon Forbes , Ewan Carr

Predictive values are measures of the clinical accuracy of a binary diagnostic test, and depend on the sensitivity and the specificity of the test and on the disease prevalence among the population being studied. This article studies…

Other Statistics · Statistics 2024-08-14 Jose Antonio Roldan-Nofuentes

Among the most important models for long-range dependent time series is the class of ARFIMA$(p,d,q)$ (Autoregressive Fractionally Integrated Moving Average) models. Estimating the long-range dependence parameter $d$ in ARFIMA models is a…

Methodology · Statistics 2026-05-11 Guilherme Pumi , Gladys Choque Ulloa , Taiane Schaedler Prass

Several statistical models are given in the form of unnormalized densities, and calculation of the normalization constant is intractable. We propose estimation methods for such unnormalized models with missing data. The key concept is to…

Machine Learning · Statistics 2020-06-11 Masatoshi Uehara , Takeru Matsuda , Jae Kwang Kim

Missing data is a common problem in practical data science settings. Various imputation methods have been developed to deal with missing data. However, even though the labels are available in the training data in many situations, the common…

Machine Learning · Computer Science 2025-01-30 Thu Nguyen , Tuan L. Vo , Pål Halvorsen , Michael A. Riegler

In an attempt to provide an answer to the increasing criticism against p-values and to bridge the gap between statistical inference and prediction modelling, we introduce the probability of improved prediction (PIP). In general, the PIP is…

Methodology · Statistics 2024-05-28 Olivier Thas , Stijn Jaspers

In this paper, prediction for linear systems with missing information is investigated. New methods are introduced to improve the Mean Squared Error (MSE) on the test set in comparison to state-of-the-art methods, through appropriate tuning…

Machine Learning · Statistics 2017-01-04 Mohammad Amin Fakharian , Ashkan Esmaeili , Farokh Marvasti

Method of moment estimators exhibit appealing statistical properties, such as asymptotic unbiasedness, for nonconvex problems. However, they typically require a large number of samples and are extremely sensitive to model misspecification.…

Computation · Statistics 2016-03-30 Dustin Tran , Minjae Kim , Finale Doshi-Velez

The imputation of missing values in time series has many applications in healthcare and finance. While autoregressive models are natural candidates for time series imputation, score-based diffusion models have recently outperformed existing…

Machine Learning · Computer Science 2021-10-28 Yusuke Tashiro , Jiaming Song , Yang Song , Stefano Ermon

Missingness and measurement frequency are two sides of the same coin. How frequent should we measure clinical variables and conduct laboratory tests? It depends on many factors such as the stability of patient conditions, diagnostic…

Machine Learning · Computer Science 2024-02-16 Jiacheng Liu , Jaideep Srivastava

This article addresses the problem of estimating the population mean in the presence of auxiliary information when study variable itself is qualitative in nature. Bias and mean squared error (MSE) expressions of the class of estimators are…

Statistics Theory · Mathematics 2013-12-12 Rajesh Singh , Prayas Sharma

We mainly study the M-estimation method for the high-dimensional linear regression model, and discuss the properties of M-estimator when the penalty term is the local linear approximation. In fact, M-estimation method is a framework, which…

Probability · Mathematics 2018-10-31 Kai Wang , Yanling Zhu

In this paper, we expand the methodology presented in Mertens et. al (2020, Biometrical Journal) to the study of life-time (survival) outcome which is subject to censoring and when imputation is used to account for missing values. We…

Methodology · Statistics 2021-05-06 Bart J. A. Mertens

The problem of missingness in observational data is ubiquitous. When the confounders are missing at random, multiple imputation is commonly used; however, the method requires congeniality conditions for valid inferences, which may not be…

Methodology · Statistics 2020-07-10 Nathan Corder , Shu Yang

Propensity score weighting is a common method for estimating treatment effects with survey data. The method is applied to minimize confounding using measured covariates that are often different between individuals in treatment and control.…

Methodology · Statistics 2026-02-06 Yukang Zeng , Fan Li , Guangyu Tong

We consider inference in models defined by approximate moment conditions. We show that near-optimal confidence intervals (CIs) can be formed by taking a generalized method of moments (GMM) estimator, and adding and subtracting the standard…

Econometrics · Economics 2021-01-15 Timothy B. Armstrong , Michal Kolesár

Electronic health records (EHR) often contain varying levels of missing data. This study compared different imputation strategies to identify the most suitable approach for predicting central line-associated bloodstream infection (CLABSI)…

Prediction models are used to predict an outcome based on input variables. Missing data in input variables often occurs at model development and at prediction time. The missForestPredict R package proposes an adaptation of the missForest…

Methodology · Statistics 2024-07-08 Elena Albu , Shan Gao , Laure Wynants , Ben Van Calster

Handling missing data in time series is a complex problem due to the presence of temporal dependence. General-purpose imputation methods, while widely used, often distort key statistical properties of the data, such as variance and…

Methodology · Statistics 2026-03-18 Guilherme Pumi , Taiane Schaedler Prass , Douglas Krauthein Verdum

Many datasets suffer from missing values due to various reasons,which not only increases the processing difficulty of related tasks but also reduces the accuracy of classification. To address this problem, the mainstream approach is to use…

Machine Learning · Computer Science 2024-08-14 Cong Guo , Chun Liu , Wei Yang
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