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Knowledge Graph-based recommendations have gained significant attention due to their ability to leverage rich semantic relationships. However, constructing and maintaining Knowledge Graphs (KGs) is resource-intensive, and the accuracy of…

Information Retrieval · Computer Science 2025-02-07 Rui Cai , Chao Wang , Qianyi Cai , Dazhong Shen , Hui Xiong

Knowledge Graph(KG) has gained traction as a machine-readable organization of real-world knowledge for analytics using artificial intelligence systems. Graph Neural Network(GNN), is proven to be an effective KG embedding technique that…

Machine Learning · Computer Science 2026-02-24 Rajesh Rajagopalamenon , Unnikrishnan Cheramangalath

Understanding how small molecules perturb gene expression is essential for uncovering drug mechanisms, predicting off-target effects, and identifying repurposing opportunities. While prior deep learning frameworks have integrated multimodal…

Machine Learning · Computer Science 2026-01-01 Pascal Passigan , Kevin Zhu , Angelina Ning

The rise of graph-structured data has driven major advances in Graph Machine Learning (GML), where graph embeddings (GEs) map features from Knowledge Graphs (KGs) into vector spaces, enabling tasks like node classification and link…

Machine Learning · Computer Science 2026-01-27 Rosario Napoli , Gabriele Morabito , Antonio Celesti , Massimo Villari , Maria Fazio

In this paper, we investigate the retrieval-augmented generation (RAG) based on Knowledge Graphs (KGs) to improve the accuracy and reliability of Large Language Models (LLMs). Recent approaches suffer from insufficient and repetitive…

Computation and Language · Computer Science 2024-04-22 Xinke Jiang , Ruizhe Zhang , Yongxin Xu , Rihong Qiu , Yue Fang , Zhiyuan Wang , Jinyi Tang , Hongxin Ding , Xu Chu , Junfeng Zhao , Yasha Wang

Knowledge Graphs (KG) and associated Knowledge Graph Embedding (KGE) models have recently begun to be explored in the context of drug discovery and have the potential to assist in key challenges such as target identification. In the drug…

Biomolecules · Quantitative Biology 2022-06-01 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Charles Tapley Hoyt , William L Hamilton

In the medical domain, several disease treatment procedures have been documented properly as a set of instructions known as Clinical Practice Guidelines (CPGs). CPGs have been developed over the years on the basis of past treatments, and…

Information Retrieval · Computer Science 2023-08-08 Vasudhan Varma Kandula , Pushpak Bhattacharyya

Regulatory compliance question answering (QA) requires precise, verifiable information, and domain-specific expertise, posing challenges for Large Language Models (LLMs). In this work, we present a novel multi-agent framework that…

Artificial Intelligence · Computer Science 2025-08-14 Bhavik Agarwal , Hemant Sunil Jomraj , Simone Kaplunov , Jack Krolick , Viktoria Rojkova

Graph Retrieval-Augmented Generation (Graph RAG) effectively builds a knowledge graph (KG) to connect disparate facts across a large document corpus. However, this broad-view approach often lacks the deep structured reasoning needed for…

Computation and Language · Computer Science 2025-10-27 Jiaoyang Li , Junhao Ruan , Shengwei Tang , Saihan Chen , Kaiyan Chang , Yuan Ge , Tong Xiao , Jingbo Zhu

Large Language Models (LLMs) exhibit strong reasoning capabilities in complex tasks. However, they still struggle with hallucinations and factual errors in knowledge-intensive scenarios like knowledge graph question answering (KGQA). We…

Computation and Language · Computer Science 2025-11-12 Songze Li , Zhiqiang Liu , Zhengke Gui , Huajun Chen , Wen Zhang

Large Language Models (LLMs) have shown strong potential in recommender systems due to their contextual learning and generalisation capabilities. Existing LLM-based recommendation approaches typically formulate the recommendation task using…

Information Retrieval · Computer Science 2025-07-09 Zeyuan Meng , Zixuan Yi , Iadh Ounis

Here we study the semantic search and retrieval problem in biomedical digital libraries. First, we introduce MedGraph, a knowledge graph embedding-based method that provides semantic relevance retrieval and ranking for the biomedical…

Information Retrieval · Computer Science 2021-12-15 Islam Akef Ebeid , Elizabeth Pierce

Knowledge graph (KG) enhanced recommendation has demonstrated improved performance in the recommendation system (RecSys) and attracted considerable research interest. Recently the literature has adopted neural graph networks (GNNs) on the…

Information Retrieval · Computer Science 2022-11-15 Liangwei Yang , Shen Wang , Jibing Gong , Shaojie Zheng , Shuying Du , Zhiwei Liu , Philip S. Yu

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

Biomedical knowledge graphs (KGs) are widely used in the life sciences, yet many are derived from unstructured documents and therefore lack schema-level constrains, whereas graphs assembled from structured resources are difficult to…

Artificial Intelligence · Computer Science 2026-05-01 Lucas Vittor , Ayush Noori , Iñaki Arango , Joaquín Polonuer , Sam Rodriques , Andrew White , David A. Clifton , Marinka Zitnik

Adoption of recently developed methods from machine learning has given rise to creation of drug-discovery knowledge graphs (KG) that utilize the interconnected nature of the domain. Graph-based modelling of the data, combined with KG…

Machine Learning · Computer Science 2022-07-27 Stephen Bonner , Ufuk Kirik , Ola Engkvist , Jian Tang , Ian P Barrett

Many Knowledege Graphs (KGs) are frequently updated, forcing their Knowledge Graph Embeddings (KGEs) to adapt to these changes. To address this problem, continual learning techniques for KGEs incorporate embeddings for new entities while…

Machine Learning · Computer Science 2026-05-29 Gerard Pons , Besim Bilalli , Anna Queralt

Knowledge graph embeddings (KGEs) were originally developed to infer true but missing facts in incomplete knowledge repositories. In this paper, we link knowledge graph completion and counterfactual reasoning via our new task CFKGR. We…

Machine Learning · Computer Science 2024-03-12 Lena Zellinger , Andreas Stephan , Benjamin Roth

Extensive adoption of electronic health records (EHRs) offers opportunities for their use in various downstream clinical analyses. To accomplish this purpose, enriching an EHR cohort with external knowledge (e.g., standardized medical…

Machine Learning · Computer Science 2024-06-13 Ahmad Wisnu Mulyadi , Heung-Il Suk

Although product graphs (PGs) have gained increasing attentions in recent years for their successful applications in product search and recommendations, the extensive power of PGs can be limited by the inevitable involvement of various…

Social and Information Networks · Computer Science 2022-02-22 Kewei Cheng , Xian Li , Yifan Ethan Xu , Xin Luna Dong , Yizhou Sun