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The rapid expansion of medical literature presents growing challenges for structuring and integrating domain knowledge at scale. Knowledge Graphs (KGs) offer a promising solution by enabling efficient retrieval, automated reasoning, and…

Computation and Language · Computer Science 2025-08-20 Duzhen Zhang , Zixiao Wang , Zhong-Zhi Li , Yahan Yu , Shuncheng Jia , Jiahua Dong , Haotian Xu , Xing Wu , Yingying Zhang , Tielin Zhang , Jie Yang , Xiuying Chen , Le Song

Electronic health records (EHRs) enable strong clinical prediction, but explanations are often coarse and hard to use for patient-level decisions. We propose a knowledge graph (KG)-guided chain-of-thought (CoT) framework for visit-level…

Artificial Intelligence · Computer Science 2026-03-03 Ruiyu Wang , Tuan Vinh , Ran Xu , Yuyin Zhou , Jiaying Lu , Carl Yang , Francisco Pasquel

Most existing knowledge graphs suffer from incompleteness. Embedding knowledge graphs into continuous vector spaces has recently attracted increasing interest in knowledge base completion. However, in most existing embedding methods, only…

Information Retrieval · Computer Science 2020-11-18 Zhenghao Zhang , Jianbin Huang , Qinglin Tan

Large language models (LLMs) often produce fluent reasoning steps while violating simple mathematical or logical constraints. We introduce MedRule-KG, a compact typed knowledge graph coupled with a symbolic verifier, designed to enforce…

Artificial Intelligence · Computer Science 2025-12-15 Crystal Su

Knowledge graphs (KGs) can be enhanced through rule mining; however, the resulting logical rules are often difficult for humans to interpret due to their inherent complexity and the idiosyncratic labeling conventions of individual KGs. This…

Computation and Language · Computer Science 2025-08-18 Nasim Shirvani-Mahdavi , Chengkai Li

Large Language Models (LLMs) excel at code generation but struggle with complex problems. Retrieval-Augmented Generation (RAG) mitigates this issue by integrating external knowledge, yet retrieval models often miss relevant context, and…

Software Engineering · Computer Science 2026-01-29 Shahd Seddik , Fahd Seddik , Iman Saberi , Fatemeh Fard , Minh Hieu Huynh , Patanamon Thongtanunam

Knowledge graphs (KGs) are powerful tools that codify relational behaviour between entities in knowledge bases. KGs can simultaneously model many different types of subject-predicate-object and higher-order relations. As such, they offer a…

Social and Information Networks · Computer Science 2020-10-27 Charilaos I. Kanatsoulis , Nicholas D. Sidiropoulos

Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

Machine Learning · Computer Science 2024-04-24 Rita T. Sousa , Heiko Paulheim

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

Knowledge Graphs (KGs), representing facts as triples, have been widely adopted in many applications. Reasoning tasks such as link prediction and rule induction are important for the development of KGs. Knowledge Graph Embeddings (KGEs)…

Artificial Intelligence · Computer Science 2021-12-17 Wen Zhang , Shumin Deng , Mingyang Chen , Liang Wang , Qiang Chen , Feiyu Xiong , Xiangwen Liu , Huajun Chen

The ability of knowledge graphs to represent complex relationships at scale has led to their adoption for various needs including knowledge representation, question-answering, and recommendation systems. Knowledge graphs are often…

Computation and Language · Computer Science 2023-05-18 Jason Youn , Ilias Tagkopoulos

Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts…

Artificial Intelligence · Computer Science 2025-05-13 Sumyyah Toonsi , Paul Schofield , Robert Hoehndorf

Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Artificial Intelligence · Computer Science 2023-07-18 Lauren Nicole DeLong , Ramon Fernández Mir , Zonglin Ji , Fiona Niamh Coulter Smith , Jacques D. Fleuriot

Integrating structured knowledge from Knowledge Graphs (KGs) into Large Language Models (LLMs) remains a key challenge for symbolic reasoning. Existing methods mainly rely on prompt engineering or fine-tuning, which lose structural fidelity…

Machine Learning · Computer Science 2025-05-13 Erica Coppolillo

Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has…

Computation and Language · Computer Science 2021-09-22 Rahul Nadkarni , David Wadden , Iz Beltagy , Noah A. Smith , Hannaneh Hajishirzi , Tom Hope

Knowledge graph-based dialogue systems can narrow down knowledge candidates for generating informative and diverse responses with the use of prior information, e.g., triple attributes or graph paths. However, most current knowledge graph…

Computation and Language · Computer Science 2020-04-21 Hongcai Xu , Junpeng Bao , Junqing Wang

Current medical retrieval-augmented generation (RAG) approaches overlook evidence-based medicine (EBM) principles, leading to two key gaps: (1) the lack of PICO alignment between queries and retrieved evidence, and (2) the absence of…

Computation and Language · Computer Science 2026-03-27 Jinning Zhang , Jie Song , Wenhui Tu , Zecheng Li , Jingxuan Li , Jin Li , Xuan Liu , Taole Sha , Zichen Wei , Yan Li

Knowledge Graphs (KGs) and their machine learning counterpart, Knowledge Graph Embedding Models (KGEMs), have seen ever-increasing use in a wide variety of academic and applied settings. In particular, KGEMs are typically applied to KGs to…

Machine Learning · Computer Science 2024-12-16 Jeffrey Sardina , John D. Kelleher , Declan O'Sullivan

Representation learning of knowledge graphs encodes entities and relation types into a continuous low-dimensional vector space, learns embeddings of entities and relation types. Most existing methods only concentrate on knowledge triples,…

Artificial Intelligence · Computer Science 2017-04-20 Mengya Wang , Hankui Zhuo , Huiling Zhu

Human smuggling networks are increasingly adaptive and difficult to analyze. Legal case documents offer valuable insights but are unstructured, lexically dense, and filled with ambiguous or shifting references-posing challenges for…

Computation and Language · Computer Science 2025-06-30 Dipak Meher , Carlotta Domeniconi , Guadalupe Correa-Cabrera