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In both criminal cases and civil cases there is an increasing demand for the analysis of DNA mixtures involving relationships. The goal might be, for example, to identify the contributors to a DNA mixture where the donors may be related, or…

Methodology · Statistics 2021-04-22 Peter J. Green , Julia Mortera

The talk describes a general approach of a genetic algorithm for multiple objective optimization problems. A particular dominance relation between the individuals of the population is used to define a fitness operator, enabling the genetic…

Artificial Intelligence · Computer Science 2008-09-03 Martin Josef Geiger

Convolutional highways are deep networks based on multiple stacked convolutional layers for feature preprocessing. We introduce an evolutionary algorithm (EA) for optimization of the structure and hyperparameters of convolutional highways…

Neural and Evolutionary Computing · Computer Science 2017-09-12 Oliver Kramer

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Deep generative models open new avenues for simulating realistic genomic data while preserving privacy and addressing data accessibility constraints. While previous studies have primarily focused on generating gene expression or haplotype…

Genomics · Quantitative Biology 2025-08-14 Sihan Xie , Thierry Tribout , Didier Boichard , Blaise Hanczar , Julien Chiquet , Eric Barrey

Feature selection plays a pivotal role in the data preprocessing and model-building pipeline, significantly enhancing model performance, interpretability, and resource efficiency across diverse domains. In population-based optimization…

Machine Learning · Computer Science 2024-08-20 Sevil Zanjani Miyandoab , Shahryar Rahnamayan , Azam Asilian Bidgoli , Sevda Ebrahimi , Masoud Makrehchi

Estimating the marginal and joint densities of the long-term average intakes of different dietary components is an important problem in nutritional epidemiology. Since these variables cannot be directly measured, data are usually collected…

Methodology · Statistics 2022-05-18 Abhra Sarkar

Decomposition-based multi-objective evolutionary algorithms (MOEAs) are widely used for solving multi-objective optimisation problems. However, their effectiveness depends on the consistency between the problems Pareto front shape and the…

Neural and Evolutionary Computing · Computer Science 2025-02-25 Xiaofeng Han , Xiaochen Chu , Tao Chao , Ming Yang , Miqing Li

We consider a multiplicative deconvolution problem, in which the density $f$ or the survival function $S^X$ of a strictly positive random variable $X$ is estimated nonparametrically based on an i.i.d. sample from a noisy observation $Y =…

Statistics Theory · Mathematics 2025-09-30 Sergio Brenner Miguel , Jan Johannes , Maximilian Siebel

Rate variation among the sites of a molecular sequence is commonly found in applications of phylogenetic inference. Several approaches exist to account for this feature but they do not usually enable the investigator to pinpoint the sites…

Quantitative Methods · Quantitative Biology 2013-05-23 Elisa Loza-Reyes , Merrilee Hurn , Tony Robinson

We describe nonparametric deconvolution models (NDMs), a family of Bayesian nonparametric models for collections of data in which each observation is the average over the features from heterogeneous particles. For example, these types of…

Machine Learning · Computer Science 2020-03-18 Allison J. B. Chaney , Archit Verma , Young-suk Lee , Barbara E. Engelhardt

Semantic diversity in Genetic Programming has proved to be highly beneficial in evolutionary search. We have witnessed a surge in the number of scientific works in the area, starting first in discrete spaces and moving then to continuous…

Neural and Evolutionary Computing · Computer Science 2021-04-15 Fergal Stapleton , Edgar Galván

Convolutional Neural Networks (CNNs) have gained a significant attraction in the recent years due to their increasing real-world applications. Their performance is highly dependent to the network structure and the selected optimization…

Neural and Evolutionary Computing · Computer Science 2019-10-01 Parsa Esfahanian , Mohammad Akhavan

Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Shahin Mohammadi , Neta Zuckerman , Andrea Goldsmith , Ananth Grama

A key challenge to make effective use of evolutionary algorithms is to choose appropriate settings for their parameters. However, the appropriate parameter setting generally depends on the structure of the optimisation problem, which is…

Neural and Evolutionary Computing · Computer Science 2020-04-02 Brendan Case , Per Kristian Lehre

Intrinsically disordered regions of proteins play a crucial role in cell signaling and drug discovery. However, their high structural flexibility makes accurate residue-level prediction challenging. Existing methods often rely on…

Neural and Evolutionary Computing · Computer Science 2026-03-09 Shaokuan Wang , Pengshan Cui , Yining Qian , An-Yang Lu , Xianpeng Wang

The electroencephalographic (EEG) signals provide highly informative data on brain activities and functions. However, their heterogeneity and high dimensionality may represent an obstacle for their interpretation. The introduction of a…

Neural and Evolutionary Computing · Computer Science 2023-10-26 Aurora Saibene , Francesca Gasparini

High-throughput genetic and epigenetic data are often screened for associations with an observed phenotype. For example, one may wish to test hundreds of thousands of genetic variants, or DNA methylation sites, for an association with…

Methodology · Statistics 2017-10-20 Eric F. Lock , David B. Dunson

The training of generative adversarial networks (GANs) is usually vulnerable to mode collapse and vanishing gradients. The evolutionary generative adversarial network (E-GAN) attempts to alleviate these issues by optimizing the learning…

Neural and Evolutionary Computing · Computer Science 2022-11-02 Junjie Li , Jingyao Li , Wenbo Zhou , Shuai Lü

For genetic algorithms using a bit-string representation of length~$n$, the general recommendation is to take $1/n$ as mutation rate. In this work, we discuss whether this is really justified for multimodal functions. Taking jump functions…

Neural and Evolutionary Computing · Computer Science 2017-03-23 Benjamin Doerr , Huu Phuoc Le , Régis Makhmara , Ta Duy Nguyen
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