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We describe an expert system, MAIES, developed for analysing forensic identification problems involving DNA mixture traces using quantitative peak area information. Peak area information is represented by conditional Gaussian distributions,…

Artificial Intelligence · Computer Science 2012-07-02 Robert G. Cowell , Steffen L. Lauritzen , Julia Mortera

About 2% of human genetic polymorphisms have been hypothesized to arise via multinucleotide mutations (MNMs), complex events that generate SNPs at multiple sites in a single generation. MNMs have the potential to accelerate the pace at…

Populations and Evolution · Quantitative Biology 2014-04-30 Kelley Harris , Rasmus Nielsen

The performance of multiobjective evolutionary algorithms (MOEAs) varies across problems, making it hard to develop new algorithms or apply existing ones to new problems. To simplify the development and application of new multiobjective…

Neural and Evolutionary Computing · Computer Science 2023-08-08 Yuri Lavinas , Marcelo Ladeira , Gabriela Ochoa , Claus Aranha

The differential evolution (DE) algorithm suffers from high computational time due to slow nature of evaluation. In contrast, micro-DE (MDE) algorithms employ a very small population size, which can converge faster to a reasonable solution.…

Neural and Evolutionary Computing · Computer Science 2016-09-27 Hojjat Salehinejad , Shahryar Rahnamayan , Hamid R. Tizhoosh

Evolutionary algorithms (EAs) have emerged as a powerful framework for optimization, especially for black-box optimization. Existing evolutionary algorithms struggle to comprehend and effectively utilize task-specific information for…

Neural and Evolutionary Computing · Computer Science 2024-12-24 Kai Wu , Xiaobin Li , Penghui Liu , Jing Liu

Detecting communities in complex networks can shed light on the essential characteristics and functions of the modeled phenomena. This topic has attracted researchers of various fields from both academia and industry. Among the different…

Social and Information Networks · Computer Science 2023-05-16 Sajjad Hesamipour , Mohammad Ali Balafar , Saeed Mousazadeh

Imaging in radioastronomy is an ill-posed inverse problem. Particularly the Event Horizon Telescope (EHT) Collaboration investigated the fidelity of their image reconstructions convincingly by large surveys solving the problem with…

Instrumentation and Methods for Astrophysics · Physics 2023-07-05 Hendrik Müller , Alejandro Mus , Andrei Lobanov

Differential evolution (DE) is a well-known type of evolutionary algorithms (EA). Similarly to other EA variants it can suffer from small populations and loose diversity too quickly. This paper presents a new approach to mitigate this…

Neural and Evolutionary Computing · Computer Science 2020-02-10 Jakub M. Tomczak , Ewelina Weglarz-Tomczak , Agoston E. Eiben

It is increasingly common clinically for cancer specimens to be examined using techniques that identify somatic mutations. In principle these mutational profiles can be used to diagnose the tissue of origin, a critical task for the 3-5% of…

Methodology · Statistics 2020-07-14 Saptarshi Chakraborty , Colin B. Begg , Ronglai Shen

The exploration of selected single nucleotide polymorphisms (SNPs) to identify genetic diversity between different sequencing population pools (Pool-seq) is a fundamental task in genetic research. As underlying sequence reads and their…

Genomics · Quantitative Biology 2021-01-05 Julia Siekiera , Stefan Kramer

A deep generative model is developed for representation and analysis of images, based on a hierarchical convolutional dictionary-learning framework. Stochastic {\em unpooling} is employed to link consecutive layers in the model, yielding…

Computer Vision and Pattern Recognition · Computer Science 2015-12-25 Yunchen Pu , Xin Yuan , Andrew Stevens , Chunyuan Li , Lawrence Carin

Multi- or many-objective evolutionary algorithm- s(MOEAs), especially the decomposition-based MOEAs have been widely concerned in recent years. The decomposition-based MOEAs emphasize convergence and diversity in a simple model and have…

Neural and Evolutionary Computing · Computer Science 2018-03-19 Yingyu Zhang , Bing Zeng , Yuanzhen Li , Junqing Li

This paper examines the use of a hierarchical coevolutionary genetic algorithm under different partnering strategies. Cascading clusters of sub-populations are built from the bottom up, with higher-level sub-populations optimising larger…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Larry Bull

The classification of DNA sequences is a key research area in bioinformatics as it enables researchers to conduct genomic analysis and detect possible diseases. In this paper, three state-of-the-art algorithms, namely Convolutional Neural…

Other Quantitative Biology · Quantitative Biology 2020-11-03 Xiangxie Zhang , Ben Beinke , Berlian Al Kindhi , Marco Wiering

Feature detection is an important procedure for image matching, where unsupervised feature detection methods are the detection approaches that have been mostly studied recently, including the ones that are based on repeatability requirement…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Chao Li , Yanan You , Wenli Zhou

Two-dimensional (2D) Multiple Signal Classification algorithm is a powerful technique for high-resolution direction-of-arrival (DOA) estimation in array signal processing. However, the exhaustive search over the 2D an-gular domain leads to…

Signal Processing · Electrical Eng. & Systems 2025-07-29 Bo Zhou , Kaijie Xu , Yinghui Quan , Mengdao Xing

Community detection in complex networks is a topic of considerable recent interest within the scientific community. For dealing with the problem that genetic algorithm are hardly applied to community detection, we propose a genetic…

Social and Information Networks · Computer Science 2013-03-25 Dongxiao He , Zhe Wang , Bin Yang , Chunguang Zhou

A hybrid evolutionary algorithm with importance sampling method is proposed for multi-dimensional optimization problems in this paper. In order to make use of the information provided in the search process, a set of visited solutions is…

Neural and Evolutionary Computing · Computer Science 2013-08-26 Guanghui Huang , Zhifeng Pan

Mutation is one of the most important stages of the genetic algorithm because of its impact on the exploration of global optima, and to overcome premature convergence. There are many types of mutation, and the problem lies in selection of…

Interrogating the evolution of biological changes at early stages of life requires longitudinal profiling of molecules, such as DNA methylation, which can be challenging with children. We introduce a probabilistic and longitudinal machine…

Genomics · Quantitative Biology 2025-04-24 Arthur Leroy , Ai Ling Teh , Frank Dondelinger , Mauricio A. Alvarez , Dennis Wang