Related papers: Dosimetric characterisation and application to rad…
Laser-plasma acceleration is an emerging technique for accelerating electrons to high energies over very short distances. The accelerated electron bunches have femtosecond duration, making them particularly relevant for applications such as…
We report the first in-air irradiations of biological samples with kHz laser-driven electrons with beam energy 20 MeV, high-energy tail extending to 40 MeV, and average dose rate up to 30 Gy/min. An in-house procedure has been developed to…
Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…
Proton beams with up to 100 pC bunch charge, 0.48 MeV cut-off energy and divergence as low as a $3^{\circ}$ were generated from solid targets at kHz repetition rate by a few-mJ femtosecond laser under controlled plasma conditions. The beam…
Ultrashort electron beams with femtosecond to picosecond bunch durations offer unique opportunities to explore active research areas ranging from ultrafast structural dynamics to ultra-high dose-rate radiobiological studies. We present a…
Irradiations at Ultra High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radio-therapy with reduced harm to normal tissues. This…
We report on the first systematic characterisation of a tuneable laser-driven electron source capable of delivering Gy-scale doses in a duration of 10 - 20 ps, thus reaching unprecedented dose rates in the range of $10^{10} - 10^{12}$ Gy/s.…
Laser plasma acceleration at kilohertz repetition rate has recently been shown to work in two different regimes, with pulse lengths of either 30 fs or 3.5 fs. We now report on a systematic study in which a large range of pulse durations and…
We show the laser-driven acceleration of unprecedented, collimated ($ 2 \ \mathrm{mrad} $ divergence), and quasi-monoenergetic ($ 25 \ \% $ energy spread) electron beams with energy up to $ 50 \ \mathrm{MeV} $ at $ 1 \ \mathrm{kHz} $…
We propose a new concept of an electron source for ultrafast electron diffraction with sub-10~fs temporal resolution. Electrons are generated in a laser-plasma accelerator, able to deliver femtosecond electron bunches at 5 MeV energy with…
Laser-plasma electron accelerators can be used to produce high-intensity X-rays, as electrons accelerated in wakefields emit radiation due to betatron oscillations.Such X-ray sources inherit the features of the electron beam;…
Laser-plasma acceleration produces ultrashort, high-brightness ion beams reaching tens of MeV, yet their large divergence and broad energy spread require dedicated capture elements for beam transport. Using laser-accelerated protons from…
Laser-driven ion acceleration provides ultra-short, high-charge, low-emittance beams, which are desirable for a wide range of high-impact applications. Yet after decades of research, a significant increase in maximum ion energy is still…
We demonstrate laser-plasma acceleration of high charge electron beams to the ~10 MeV scale using ultrashort laser pulses with as little energy as 10 mJ. This result is made possible by an extremely dense and thin hydrogen gas jet. Total…
We report on the first simultaneous measurement of high-order harmonics, relativistic electrons and low divergence proton beams generated from plasma mirrors driven at kHz repetition rate by relativistic-intensity milliJoule-energy…
We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and cell-culture FLASH radiobiology experiments. UHDR electron beams were controlled by a…
We report on the stable and continuous operation of a kilohertz laser-plasma accelerator. Electron bunches with 2.6 pC charge and 2.5 MeV peak energy were generated via injection and trapping in a downward plasma density ramp. This density…
Relativistic interaction of short-pulse lasers with underdense plasmas has recently led to the emergence of a novel generation of femtosecond x-ray sources. Based on radiation from electrons accelerated in plasma, these sources have the…
Radiotherapy using very high-energy electron (VHEE) beams generated by a laser-plasma accelerator has garnered significant interest due to its dose distribution capabilities and potential to address limitations of traditional photon-based…
Recent studies have demonstrated the possibility of accelerating electrons to MeV energies in ambient air using tightly focused laser configurations. In this article, we explore possible strategies to control and optimize the resulting…