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Causal discovery can be a powerful tool for investigating causality when a system can be observed but is inaccessible to experiments in practice. Despite this, it is rarely used in any scientific or medical fields. One of the major hurdles…

Machine Learning · Statistics 2019-10-07 Erich Kummerfeld , Alexander Rix

Identification of features is a critical task in microbiome studies that is complicated by the fact that microbial data are high dimensional and heterogeneous. Masked by the complexity of the data, the problem of separating signals from…

Methodology · Statistics 2020-09-18 Liangliang Zhang , Yushu Shi , Kim-Anh Do , Christine B. Peterson , Robert R. Jenq

We introduce a novel framework for uncertainty quantification in clustering that combines martingale posterior distributions with density-based clustering. Unlike classical model-based approaches, which define clusters at the latent level…

Machine Learning · Statistics 2026-04-20 Nicola Bariletto , Stephen G. Walker

The permutation test is an often used test procedure in brain imaging. Unfortunately, generating every possible permutation for large-scale brain image datasets such as HCP and ADNI with hundreds images is not practical. Many previous…

Computation · Statistics 2019-04-10 Moo K. Chung , Yixian Wang , Shih-Gu Huang , Ilwoo Lyu

We propose a method that combines signals from many brain regions observed in functional Magnetic Resonance Imaging (fMRI) to predict the subject's behavior during a scanning session. Such predictions suffer from the huge number of brain…

Computer Vision and Pattern Recognition · Computer Science 2011-04-29 Vincent Michel , Alexandre Gramfort , Gaël Varoquaux , Evelyn Eger , Christine Keribin , Bertrand Thirion

Kernel-based hypothesis tests offer a flexible, non-parametric tool to detect high-order interactions in multivariate data, beyond pairwise relationships. Yet the scalability of such tests is limited by the computationally demanding…

Methodology · Statistics 2025-06-09 Zhaolu Liu , Robert L. Peach , Mauricio Barahona

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

Permutation tests are widely used for statistical hypothesis testing when the sampling distribution of the test statistic under the null hypothesis is analytically intractable or unreliable due to finite sample sizes. One critical challenge…

Computation · Statistics 2023-08-29 Yang Shi , Huining Kang , Ji-Hyun Lee , Hui Jiang

When permutation methods are used in practice, often a limited number of random permutations are used to decrease the computational burden. However, most theoretical literature assumes that the whole permutation group is used, and methods…

Statistics Theory · Mathematics 2018-08-20 Jesse Hemerik , Jelle Goeman

This paper considers clustered multi-task compressive sensing, a hierarchical model that solves multiple compressive sensing tasks by finding clusters of tasks that leverage shared information to mutually improve signal reconstruction. The…

Signal Processing · Electrical Eng. & Systems 2023-10-03 Alexander Lin , Demba Ba

Throughout the last decade, random forests have established themselves as among the most accurate and popular supervised learning methods. While their black-box nature has made their mathematical analysis difficult, recent work has…

Methodology · Statistics 2019-12-10 Tim Coleman , Wei Peng , Lucas Mentch

The permutation test is known as the exact test procedure in statistics. However, often it is not exact in practice and only an approximate method since only a small fraction of every possible permutation is generated. Even for a small…

Functional magnetic resonance imaging (fMRI) produces data about activity inside the brain, from which spatial maps can be extracted by independent component analysis (ICA). In datasets, there are n spatial maps that contain p voxels. The…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Tuomo Sipola , Fengyu Cong , Tapani Ristaniemi , Vinoo Alluri , Petri Toiviainen , Elvira Brattico , Asoke K. Nandi

The problem of identifying regions of spatially interesting, different or adversarial behavior is inherent to many practical applications involving distributed multisensor systems. In this work, we develop a general framework stemming from…

Signal Processing · Electrical Eng. & Systems 2022-06-14 Martin Gölz , Abdelhak M. Zoubir , Visa Koivunen

We propose a test for a change in the mean for a sequence of functional observations that are only partially observed on subsets of the domain, with no information available on the complement. The framework accommodates important scenarios,…

Methodology · Statistics 2025-10-10 Šárka Hudecová , Claudia Kirch

Multi-compartment modeling of diffusion-weighted magnetic resonance imaging measurements is necessary for accurate brain connectivity analysis. Existing methods for estimating the number and orientations of fascicles in an imaging voxel…

Image and Video Processing · Electrical Eng. & Systems 2020-06-22 Davood Karimi , Lana Vasung , Camilo Jaimes , Fedel Machado-Rivas , Shadab Khan , Simon K. Warfield , Ali Gholipour

Researchers often have datasets measuring features $x_{ij}$ of samples, such as test scores of students. In factor analysis and PCA, these features are thought to be influenced by unobserved factors, such as skills. Can we determine how…

Statistics Theory · Mathematics 2019-09-16 Edgar Dobriban

Measuring the breadth of a word's meaning, or its spread across contexts, has become feasible with contextualized token embeddings. A word type can be represented as a cloud of token vectors, with dispersion-based statistics serving as…

Computation and Language · Computer Science 2026-05-11 Yo Ehara

In the big data era, the need to reevaluate traditional statistical methods is paramount due to the challenges posed by vast datasets. While larger samples theoretically enhance accuracy and hypothesis testing power without increasing false…

Methodology · Statistics 2026-01-09 Xuekui Zhang , Li Xing , Jing Zhang , Soojeong Kim

Gene expression data is often collected in time series experiments, under different experimental conditions. There may be genes that have very different gene expression profiles over time, but that adjust their gene expression patterns in…

Methodology · Statistics 2021-12-02 Susana Conde , Shahin Tavakoli , Daphne Ezer