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The emergence of a body axis is a fundamental step in the development of multicellular organisms. In simple systems such as $\textit{Hydra}$, growing evidence suggests that mechanical forces generated by collective cellular activity play a…

Soft Condensed Matter · Physics 2026-01-09 Arthur Hernandez , Cuncheng Zhu , Luca Giomi

State of the art reinforcement learning methods sometimes encounter unsafe situations. Identifying when these situations occur is of interest both for post-hoc analysis and during deployment, where it might be advantageous to call out to a…

Machine Learning · Computer Science 2025-05-29 Alexander Grushin , Walt Woods , Alvaro Velasquez , Simon Khan

We study the threshold control protocol for a collective flashing ratchet. In particular, we analyze the dependence of the current on the values of the thresholds. We have found analytical expressions for the small threshold dependence both…

Statistical Mechanics · Physics 2007-05-23 M. Feito , F. J. Cao

Behavior cloning provides strong imitation learning guarantees when training and test environments share the same dynamics. However, in many deployment settings the test environment's transitions differ from training, and classical offline…

Machine Learning · Computer Science 2026-05-19 Surbhi Goel , Jonathan Pei , James Wang

We consider expected risk minimization in multi-agent systems comprised of distinct subsets of agents operating without a common time-scale. Each individual in the network is charged with minimizing the global objective function, which is…

Optimization and Control · Mathematics 2017-12-12 Amrit Singh Bedi , Alec Koppel , Ketan Rajawat

Neurons in the brain are complex machines with distinct functional compartments that interact nonlinearly. In contrast, neurons in artificial neural networks abstract away this complexity, typically down to a scalar activation function of a…

Machine Learning · Computer Science 2021-10-18 Kijung Yoon , Emin Orhan , Juhyun Kim , Xaq Pitkow

A method based on deep artificial neural networks and empirical risk minimization is developed to calculate the boundary separating the stopping and continuation regions in optimal stopping. The algorithm parameterizes the stopping boundary…

Pricing of Securities · Quantitative Finance 2023-05-26 A. Max Reppen , H. Mete Soner , Valentin Tissot-Daguette

Active sensing is traditionally defined as the expenditure of energy, typically in the form of movement, for obtaining information. Here, we propose that the combination of reliance on adaptive sensors, the linkage between movement and…

Neurons and Cognition · Quantitative Biology 2026-05-25 Andrew Lamperski , Debojyoti Biswas , Eric S. Fortune , John Guckenheimer , Kathleen Hoffman , Noah J. Cowan

Quasiperiodic systems offer an appealing intermediate between long-range ordered and genuine disordered systems, with unusual critical properties. One-dimensional models that break the so-called self-dual symmetry usually display a mobility…

Quantum Gases · Physics 2022-04-26 Hepeng Yao , Alice Khoudli , Léa Bresque , Laurent Sanchez-Palencia

We consider a threshold-crossing spiking process as a simple model for the activity within a population of neurons. Assuming that these neurons are driven by a common fluctuating input with Gaussian statistics, we evaluate the…

Neurons and Cognition · Quantitative Biology 2009-06-11 Yoram Burak , Sam Lewallen , Haim Sompolinsky

Understanding the characteristics of neural networks is important but difficult due to their complex structures and behaviors. Some previous work proposes to transform neural networks into equivalent Boolean expressions and apply…

Machine Learning · Computer Science 2023-06-09 Yiping Tang , Kohei Hatano , Eiji Takimoto

This paper outlines a methodological approach for designing adaptive agents driving themselves near points of criticality. Using a synthetic approach we construct a conceptual model that, instead of specifying mechanistic requirements to…

Adaptation and Self-Organizing Systems · Physics 2017-12-14 Miguel Aguilera , Manuel G. Bedia

We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The condition expresses a balance between ion channels that…

Neurons and Cognition · Quantitative Biology 2015-06-11 Alessio Franci , Guillaume Drion , Vincent Seutin , Rodolphe Sepulchre

In this paper, we propose a new threshold-kernel jump-detection method for jump-diffusion processes, which iteratively applies thresholding and kernel methods in an approximately optimal way to achieve improved finite-sample performance. We…

Statistics Theory · Mathematics 2020-04-07 José E. Figueroa-López , Cheng Li , Jeffrey Nisen

In this paper we study a class of stochastic chemical reaction networks (CRNs) for which chemical species are created by a sequence of chain reactions. We prove that under some convenient conditions on the initial state, some of these…

Probability · Mathematics 2024-06-19 Lucie Laurence , Philippe Robert

An application of optimal control theory results in a lower bound on the speed $|\dot{\lambda}(t)|$ that must be attained at least once by any external forcing function that induces tipping in the asymptotically autonomous scalar ODE…

Dynamical Systems · Mathematics 2023-12-19 Grace Zhang

The topology of artificial neural networks has a significant effect on their performance. Characterizing efficient topology is a field of promising research in Artificial Intelligence. However, it is not a trivial task and it is mainly…

Neural and Evolutionary Computing · Computer Science 2022-05-23 Fabien Furfaro , Avner Bar-Hen , Geoffroy Berthelot

Spiking Neural Networks (SNNs) offer low-latency and energy-efficient decision making on neuromorphic hardware, making them attractive for Reinforcement Learning (RL) in resource-constrained edge devices. However, most RL algorithms for…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Zijie Xu , Tong Bu , Zecheng Hao , Jianhao Ding , Zhaofei Yu

Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and…

Cell Behavior · Quantitative Biology 2016-12-26 Indrani Bose , Mainak Pal

Understanding the condensed-phase behavior of chiral molecules is important in biology, as well as in a range of technological applications, such as the manufacture of pharmaceuticals. Here, we use molecular dynamics simulations to study a…

Statistical Mechanics · Physics 2023-12-27 Pablo M. Piaggi , Roberto Car , Frank H. Stillinger , Pablo G. Debenedetti
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