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Alzheimer's disease is one of the diseases that mostly affects older people without being a part of aging. The most common symptoms include problems with communicating and abstract thinking, as well as disorientation. It is important to…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Fatih Altay , Guillermo Ramon Sanchez , Yanli James , Stephen V. Faraone , Senem Velipasalar , Asif Salekin

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that leads to dementia, and early intervention can greatly benefit from analyzing linguistic abnormalities. In this work, we explore the potential of Large Language Models…

Computation and Language · Computer Science 2025-12-23 Chuyuan Li , Raymond Li , Thalia S. Field , Giuseppe Carenini

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

In this paper, we develop a 2D and 3D segmentation pipelines for fully automated cardiac MR image segmentation using Deep Convolutional Neural Networks (CNN). Our models are trained end-to-end from scratch using the ACD Challenge 2017…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Jay Patravali , Shubham Jain , Sasank Chilamkurthy

In recent years, deep convolutional neural networks (CNNs) have shown record-shattering performance in a variety of computer vision problems, such as visual object recognition, detection and segmentation. These methods have also been…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Jose Bernal , Kaisar Kushibar , Daniel S. Asfaw , Sergi Valverde , Arnau Oliver , Robert Martí , Xavier Lladó

Alzheimer's disease (AD) is the most prevalent form of dementia. Traditional methods cannot achieve efficient and accurate diagnosis of AD. In this paper, we introduce a novel method based on dynamic functional connectivity (dFC) that can…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Xingwei An , Yutao Zhou , Yang Di , Dong Ming

The application of deep learning-based architecture has seen a tremendous rise in recent years. For example, medical image classification using deep learning achieved breakthrough results. Convolutional Neural Networks (CNNs) are…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Ganga Prasad Basyal , David Zeng , Bhaskar Pm Rimal

Adequate blood supply is critical for normal brain function. Brain vasculature dysfunctions such as stalled blood flow in cerebral capillaries are associated with cognitive decline and pathogenesis in Alzheimer's disease. Recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Roman Solovyev , Alexandr A. Kalinin , Tatiana Gabruseva

In recent years, deep learning methods have achieved great success in various fields due to their strong performance in practical applications. In this paper, we present a light-weight neural network for Parkinson's disease diagnostics, in…

This paper presents a tutorial of an explainable approach using Convolutional Neural Network (CNN) and Gradient-weighted Class Activation Mapping (Grad-CAM) to classify four progressive dementia stages based on open MRI brain images. The…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Kevin Kam Fung Yuen

In medical-data driven learning, 3D convolutional neural networks (CNNs) have started to show superior performance to 2D CNNs in numerous deep learning tasks, proving the added value of 3D spatial information in feature representation.…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Xin Wang , Ruisheng Su , Weiyi Xie , Wenjin Wang , Yi Xu , Ritse Mann , Jungong Han , Tao Tan

Alzheimers disease progresses slowly and involves complex interaction between various biological factors. Longitudinal medical imaging data can capture this progression over time. However, longitudinal data frequently encounter issues such…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Duy-Phuong Dao , Hyung-Jeong Yang , Jahae Kim

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

Machine Learning · Computer Science 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

High-resolution (HR) magnetic resonance imaging (MRI) provides detailed anatomical information that is critical for diagnosis in the clinical application. However, HR MRI typically comes at the cost of long scan time, small spatial…

Computer Vision and Pattern Recognition · Computer Science 2020-03-10 Yuhua Chen , Anthony G. Christodoulou , Zhengwei Zhou , Feng Shi , Yibin Xie , Debiao Li

Background: Alzheimers disease is a progressive neurodegenerative disorder and the main cause of dementia in aging. Hippocampus is prone to changes in the early stages of Alzheimers disease. Detection and observation of the hippocampus…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Hossein Yousefi-Banaem , Saber Malekzadeh

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot…

Machine Learning · Computer Science 2019-03-25 Jack Albright

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power…

Machine Learning · Computer Science 2025-11-11 Richard Hou , Shengpu Tang , Wei Jin

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Quantitative Methods · Quantitative Biology 2020-10-07 Sema Candemir , Xuan V. Nguyen , Luciano M. Prevedello , Matthew T. Bigelow , Richard D. White , Barbaros S. Erdal