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We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…

Visible light optical coherence tomography (vis-OCT) provides a unique tool for imaging the structure and oxygen metabolism in tissues. However, since it works in the spectral domain, vis-OCT still suffers from noises due to the multiple…

Medical Physics · Physics 2021-12-28 Danlei Qiao , Peng Miao , Ian Rubinoff , Jibo Zhou , John B. Troy , Hao F. Zhang , Shanbao Tong

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic

Optical coherence tomography (OCT) is a powerful technology for rapid volumetric imaging in biomedicine. The bright field imaging approach of conventional OCT systems is based on the detection of directly backscattered light, thereby…

Silicon photonic integrated circuit (PIC) builds on the demand for a low cost approach from established silicon-based manufacturing infrastructure traditionally built for electronics. Besides its natural abundance, silicon has desirable…

Applied Physics · Physics 2024-05-06 James Y. S. Tan , Shawn Xie Wu , Salih Yanikgonul , Chao Li , Patrick Guo-Qiang Lo

Optical coherence tomography (OCT) can perform non-invasive high-resolution three-dimensional (3D) imaging and has been widely used in biomedical fields, while it is inevitably affected by coherence speckle noise which degrades OCT imaging…

Optics · Physics 2025-06-30 Renxiong Wu , Fei Zheng , Meixuan Li , Shaoyan Huang , Xin Ge , Linbo Liu , Yong Liu , Guangming Ni

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal…

Instrumentation and Detectors · Physics 2023-11-28 Chao Xu , Xin Guan , Syeda Aimen Abbasi , Neng Xia , To Ngai , Li Zhang , Ho-Pui Ho , Sze Hang Calvin Ng , Wu Yuan

Optical coherence tomography (OCT) has proven to be a powerful technique for studying tissue morphology in ophthalmology, cardiology, and endomicroscopy. Its performance is limited by the fundamental trade-off between the imaging…

Optics · Physics 2008-02-27 Keisuke Goda , Daniel R. Solli , Bahram Jalali

Optical diffraction tomography (ODT) is a powerful technique for quantitative, label-free reconstruction of the three-dimensional refractive index (RI) distribution of biological samples. While ODT is well established for imaging thin,…

A new formulation of lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are presented. The formulation is based on a mathematical sample…

Whole-eye optical coherence tomography (WEOCT) has emerged as a transformative imaging modality capable of simultaneously capturing the anterior and posterior segments of the human eye. WEOCT enables comprehensive ocular biometry, which is…

Akinetic swept-sources are essential for high-speed optical coherence tomography (OCT) imaging. Time-stretched supercontinuum (TSSC) lasers have proven to be efficient for multi-MHz swept-sources. However, lack of low-noise broadband lasers…

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

Photonic integrated circuits (PICs) are attractive platforms to perform large-scale quantum information processing. While highly-functional PICs (e.g. silicon based photonic-circuits) and high-performance single photon sources (SPSs, e.g.…

Applied Physics · Physics 2019-06-18 Ryota Katsumi , Yasutomo Ota , Masahiro Kakuda , Satoshi Iwamoto , Yasuhiko Arakawa

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

Spectral Domain Optical Coherence Tomography (SD-OCT) is a well-known imaging modality which allows for \textit{in-vivo} visualization of the morphology of different biological tissues at cellular level resolutions. The overall SD-OCT…

Optical Coherence Tomography (OCT) has become one of the most used imaging modality in ophthalmology. It provides high-resolution, non-invasive visualization of retinal microarchitecture. The automated analysis of OCT images through…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Hedi Tabia , Désiré Sidibé , Nawres Khlifa , Ahmed Tabia , Ines Rahmany , Noura Aboudi , Zainab Haddad , Hajer Khachnaoui , Hsouna Zgolli

Serial sectioning Optical Coherence Tomography (sOCT) is a high-throughput, label free microscopic imaging technique that is becoming increasingly popular to study post-mortem neurovasculature. Quantitative analysis of the vasculature…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Etienne Chollet , Yael Balbastre , Caroline Magnain , Bruce Fischl , Hui Wang

Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. OCT images usually suffer from a granular pattern, called speckle noise,…

Computer Vision and Pattern Recognition · Computer Science 2016-05-25 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…