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Related papers: Batch Optimization for DNA Synthesis

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Batch Normalization (BN) is an important preprocessing step to many deep learning applications. Since it is a data-dependent process, for some homogeneous datasets it is a redundant or even a performance-degrading process. In this paper, we…

Machine Learning · Computer Science 2022-12-01 Wael Alsobhi , Tarik Alafif , Alaa Abdel-Hakim , Weiwei Zong

Deep neural networks (DNNs) frequently contain far more weights, represented at a higher precision, than are required for the specific task which they are trained to perform. Consequently, they can often be compressed using techniques such…

Machine Learning · Computer Science 2020-12-03 Vinu Joseph , Saurav Muralidharan , Animesh Garg , Michael Garland , Ganesh Gopalakrishnan

Distributed in-memory data processing engines accelerate iterative applications by caching substantial datasets in memory rather than recomputing them in each iteration. Selecting a suitable cluster size for caching these datasets plays an…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-07 Hani Al-Sayeh , Muhammad Attahir Jibril , Bunjamin Memishi , Kai-Uwe Sattler

We consider error-correcting coding for deoxyribonucleic acid (DNA)-based storage using nanopore sequencing. We model the DNA storage channel as a sampling noise channel where the input data is chunked into $M$ short DNA strands, which are…

Information Theory · Computer Science 2024-06-21 Lorenz Welter , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

We present a finite blocklength performance bound for a DNA storage channel with insertions, deletions, and substitutions. The considered bound -- the dependency testing (DT) bound, introduced by Polyanskiy et al. in 2010 -- provides an…

Information Theory · Computer Science 2023-08-07 Issam Maarouf , Gianluigi Liva , Eirik Rosnes , Alexandre Graell i Amat

The biochemical processes underlying DNA data storage, including synthesis, amplification, and sequencing, are inherently noisy. Consequently, base-level insertion, deletion, and substitution (IDS) errors, as well as sequence-level…

Information Theory · Computer Science 2026-03-17 Ramy Khabbaz , Jérémy Mateos , Marc Antonini , Serge Kas Hanna

Owing to its immense storage density and durability, DNA has emerged as a promising storage medium. However, due to technological constraints, data can only be written onto many short DNA molecules called data blocks that are stored in an…

Information Theory · Computer Science 2024-03-26 Shubhransh Singhvi , Charchit Gupta , Avital Boruchovsky , Yuval Goldberg , Han Mao Kiah , Eitan Yaakobi

With the rapid increase of available digital data, DNA storage is identified as a storage media with high density and capability of long-term preservation, especially for archival storage systems. However, the encoding density (i.e., how…

Emerging Technologies · Computer Science 2021-08-26 Bingzhe Li , Li Ou , David Du

The task of RNA design given a target structure aims to find a sequence that can fold into that structure. It is a computationally hard problem where some version(s) have been proven to be NP-hard. As a result, heuristic methods such as…

Biomolecules · Quantitative Biology 2024-12-13 Wei Yu Tang , Ning Dai , Tianshuo Zhou , David H. Mathews , Liang Huang

Program synthesis aims to {\it automatically} find programs from an underlying programming language that satisfy a given specification. While this has the potential to revolutionize computing, how to search over the vast space of programs…

Neural and Evolutionary Computing · Computer Science 2022-03-01 Yuan Yuan , Wolfgang Banzhaf

Strings are a natural representation of biological data such as DNA, RNA and protein sequences. The problem of finding a string that summarizes a set of sequences has direct application in relative compression algorithms for genome and…

Data Structures and Algorithms · Computer Science 2019-12-06 P. Mirabal , J. Abreu , D. Seco

Minimization of the number of cluster heads in a wireless sensor network is a very important problem to reduce channel contention and to improve the efficiency of the algorithm when executed at the level of cluster-heads. In this paper, we…

Networking and Internet Architecture · Computer Science 2011-04-05 Ehsan Heidari , Ali Movaghar

Ever since deoxyribonucleic acid (DNA) was considered as a next-generation data-storage medium, lots of research efforts have been made to correct errors occurred during the synthesis, storage, and sequencing processes using error…

Information Theory · Computer Science 2023-06-14 Jaeho Jeong , Hosung Park , Hee-Youl Kwak , Jong-Seon No , Hahyeon Jeon , Jeong Wook Lee , Jae-Won Kim

High throughput technologies have become the practice of choice for comparative studies in biomedical applications. Limited number of sample points due to sequencing cost or access to organisms of interest necessitates the development of…

Methodology · Statistics 2018-07-17 Ariana Broumand , Siamak Zamani Dadaneh

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

Inspired by the principle of deliberate practice in human learning, we propose Deliberate Practice for Synthetic Data Generation (DP), a novel framework that improves sample efficiency through dynamic synthetic data generation. Prior work…

Increasing the mini-batch size for stochastic gradient descent offers significant opportunities to reduce wall-clock training time, but there are a variety of theoretical and systems challenges that impede the widespread success of this…

In this paper we propose a novel network adaption method called Differentiable Network Adaption (DNA), which can adapt an existing network to a specific computation budget by adjusting the width and depth in a differentiable manner. The…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Shaopeng Guo , Yujie Wang , Kun Yuan , Quanquan Li

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2022-05-10 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

Batch normalization (BN) is a popular and ubiquitous method in deep learning that has been shown to decrease training time and improve generalization performance of neural networks. Despite its success, BN is not theoretically well…

Machine Learning · Computer Science 2022-01-21 Susanna Lange , Kyle Helfrich , Qiang Ye