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The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

Quantitative Methods · Quantitative Biology 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and tradeoffs of DNA-based storage systems under a simple model, motivated by current…

Information Theory · Computer Science 2017-05-16 Reinhard Heckel , Ilan Shomorony , Kannan Ramchandran , David N. C. Tse

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

Dataset distillation is a newly emerging task that synthesizes a small-size dataset used in training deep neural networks (DNNs) for reducing data storage and model training costs. The synthetic datasets are expected to capture the essence…

Computer Vision and Pattern Recognition · Computer Science 2023-11-06 Jiawei Du , Qin Shi , Joey Tianyi Zhou

In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

Information Theory · Computer Science 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

Generative data-free quantization emerges as a practical compression approach that quantizes deep neural networks to low bit-width without accessing the real data. This approach generates data utilizing batch normalization (BN) statistics…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Haotong Qin , Yifu Ding , Xiangguo Zhang , Jiakai Wang , Xianglong Liu , Jiwen Lu

Large-scale supervised classification algorithms, especially those based on deep convolutional neural networks (DCNNs), require vast amounts of training data to achieve state-of-the-art performance. Decreasing this data requirement would…

Computer Vision and Pattern Recognition · Computer Science 2016-06-15 Maya Kabkab , Azadeh Alavi , Rama Chellappa

Recently, convergence as well as convergence rate analyses of deep learning optimizers for nonconvex optimization have been widely studied. Meanwhile, numerical evaluations for the optimizers have precisely clarified the relationship…

Optimization and Control · Mathematics 2021-08-27 Hideaki Iiduka

DNA is not only the genetic material of life, but also a favorable material for a new computing model. Various research works based on DNA computing have been carried out in recent years. DNA sequence design is the foundation of such…

Emerging Technologies · Computer Science 2023-11-10 Yao Yao , Xun Zhang , Xin Liu , Yuan Liu , Xiaokang Zhang , Qiang Zhang

DNA strands serve as a storage medium for $4$-ary data over the alphabet $\{A,T,G,C\}$. DNA data storage promises formidable information density, long-term durability, and ease of replicability. However, information in this intriguing…

Information Theory · Computer Science 2024-08-06 Canberk İrimağzı , Yusuf Uslan , Ahmed Hareedy

Recent advances in the theoretical understanding of SGD led to a formula for the optimal batch size minimizing the number of effective data passes, i.e., the number of iterations times the batch size. However, this formula is of no…

Machine Learning · Computer Science 2021-11-22 Motasem Alfarra , Slavomir Hanzely , Alyazeed Albasyoni , Bernard Ghanem , Peter Richtarik

Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to…

Quantitative Methods · Quantitative Biology 2014-03-05 Fabien Campagne , Kevin C. Dorff , Nyasha Chambwe , James T. Robinson , Jill P. Mesirov , Thomas D. Wu

To increase the information capacity of DNA storage, composite DNA letters were introduced. We propose a novel channel model for composite DNA in which composite sequences are decomposed into ordered standard non-composite sequences. The…

Information Theory · Computer Science 2025-10-31 Besart Dollma , Ohad Elishco , Eitan Yaakobi

We study the amount of reliable information that can be stored in a DNA-based storage system composed of short DNA molecules. In this regime, Shomorony and Heckel (2022) put forward a conjecture on the scaling of the number of information…

Information Theory · Computer Science 2025-11-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

Batching has a fundamental influence on the efficiency of deep neural network (DNN) execution. However, for dynamic DNNs, efficient batching is particularly challenging as the dataflow graph varies per input instance. As a result,…

Machine Learning · Computer Science 2023-02-09 Siyuan Chen , Pratik Fegade , Tianqi Chen , Phillip B. Gibbons , Todd C. Mowry

DNA tile self-assembly has emerged as a rich and promising primitive for nano-technology. This paper studies the problems of minimizing assembly time and error rate by changing the tile concentrations because changing the tile…

Data Structures and Algorithms · Computer Science 2012-10-23 Ho-Lin Chen , Ming-Yang Kao

In DNA-based data storage, DNA codes with biochemical constraints and error correction are designed to protect data reliability. Single-stranded DNA sequences with secondary structure avoidance (SSA) help to avoid undesirable secondary…

Information Theory · Computer Science 2023-07-04 Shu Liu , Chaoping Xing , Yaqian Zhang

DNA storage has emerged as an important area of research. The reliability of DNA storage system depends on designing the DNA strings (called DNA codes) that are sufficiently dissimilar. In this work, we introduce DNA codes that satisfy a…

Information Theory · Computer Science 2022-11-28 Krishna Gopal Benerjee , Sourav Deb , Manish K Gupta

In modern deep learning models, long training times and large datasets present significant challenges to both efficiency and scalability. Effective data curation and sample selection are crucial for optimizing the training process of deep…

Machine Learning · Computer Science 2024-12-24 Mohammadreza Sharifi

The exponentially increasing demand for data storage has been facing more and more challenges during the past years. The energy costs that it represents are also increasing, and the availability of the storage hardware is not able to follow…

Image and Video Processing · Electrical Eng. & Systems 2022-03-21 Xavier Pic , Marc Antonini