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The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately…

Prostate cancer (PCa) is the second deadliest form of cancer in males, and it can be clinically graded by examining the structural representations of Gleason tissues. This paper proposes \RV{a new method} for segmenting the Gleason tissues…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Taimur Hassan , Bilal Hassan , Ayman El-Baz , Naoufel Werghi

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

The Gleason scoring system is the primary diagnostic and prognostic tool for prostate cancer. In recent years, with the development of digitisation devices, the use of computer vision techniques for the analysis of biopsies has increased.…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Julio Silva-Rodríguez , Adrián Colomer , María A. Sales , Rafael Molina , Valery Naranjo

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Prostate cancer is one of the main diseases affecting men worldwide. The Gleason scoring system is the primary diagnostic tool for prostate cancer. This is obtained via the visual analysis of cancerous patterns in prostate biopsies…

Image and Video Processing · Electrical Eng. & Systems 2021-05-24 Julio Silva-Rodríguez , Adrián Colomer , Valery Naranjo

Data augmentation refers to a group of techniques whose goal is to battle limited amount of available data to improve model generalization and push sample distribution toward the true distribution. While different augmentation strategies…

Quantitative Methods · Quantitative Biology 2020-06-03 Ruqian Hao , Khashayar Namdar , Lin Liu , Masoom A. Haider , Farzad Khalvati

Whole slide images~(WSIs) are digitized images of tissues placed in glass slides using advanced scanners. The digital processing of WSIs is challenging as they are gigapixel images and stored in multi-resolution format. A common challenge…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Prostate cancer ranks among the leading health issues impacting men, with the Gleason scoring system serving as the primary method for diagnosis and prognosis. This system relies on expert pathologists to evaluate samples of prostate tissue…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Amin Malekmohammadi , Ali Badiezadeh , Seyed Mostafa Mirhassani , Parisa Gifani , Majid Vafaeezadeh

Despite considerable progress in developing artificial intelligence (AI) algorithms for prostate cancer detection from whole slide images, the clinical applicability of these models remains limited due to variability in pathological…

Tissues and Organs · Quantitative Biology 2024-06-12 T. J. Hart , Chloe Engler Hart , Spencer Hopson , Paul M. Urie , Dennis Della Corte

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Prostate cancer grading using the ISUP system (International Society of Urological Pathology) for treatment decisions is highly subjective and requires considerable expertise. Despite advances in computer-aided diagnosis systems, few have…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Riddhasree Bhattacharyya , Surochita Pal Das , Sushmita Mitra

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Colorectal and prostate cancers are the most common types of cancer in men worldwide. To diagnose colorectal and prostate cancer, a pathologist performs a histological analysis on needle biopsy samples. This manual process is time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2023-01-31 Remy Peyret , Duaa alSaeed , Fouad Khelifi , Nadia Al-Ghreimil , Heyam Al-Baity , Ahmed Bouridane

Prostate cancer (PCa) was the most frequently diagnosed cancer among American men in 2023. The histological grading of biopsies is essential for diagnosis, and various deep learning-based solutions have been developed to assist with this…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Anthony Sisk , Yang Zong , Kimberly Flores , William Speier , Corey W. Arnold

Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Sunghwan Yoo , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

Prostate cancer is a commonly diagnosed cancerous disease among men world-wide. Even with modern technology such as multi-parametric magnetic resonance tomography and guided biopsies, the process for diagnosing prostate cancer remains time…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Malte Rippa , Ruben Schulze , Marian Himstedt , Felice Burn

We propose a novel automatic method for accurate segmentation of the prostate in T2-weighted magnetic resonance imaging (MRI). Our method is based on convolutional neural networks (CNNs). Because of the large variability in the shape, size,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-01 Davood Karimi , Golnoosh Samei , Yanan Shao , Septimiu Salcudean