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Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

The correlation of optical measurements with a correct pathology label is often hampered by imprecise registration caused by deformations in histology images. This study explores an automated multi-modal image registration technique…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Lianne Feenstra , Maud Lambregts , Theo J. M Ruers , Behdad Dashtbozorg

Cardiac deformation is a crucial biomarker for the evaluation of cardiac function. Current methods for estimating cardiac strain might underestimate local deformation due to through-plane motion and segmental averaging. Mesh-based mapping…

Tissues and Organs · Quantitative Biology 2025-04-07 Beatrice Moscoloni , Patrick Segers , Mathias Peirlinck

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Jiashun Chen , Donghuan Lu , Yu Zhang , Dong Wei , Munan Ning , Xinyu Shi , Zhe Xu , Yefeng Zheng

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

Traditional deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-03-15 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

The recent application of deep learning in various areas of medical image analysis has brought excellent performance gains. In particular, technologies based on deep learning in medical image registration can outperform traditional…

Image and Video Processing · Electrical Eng. & Systems 2019-09-09 Abdullah Nazib , Clinton Fookes , Dimitri Perrin

Deformable image registration and regression are important tasks in medical image analysis. However, they are computationally expensive, especially when analyzing large-scale datasets that contain thousands of images. Hence, cluster…

Computer Vision and Pattern Recognition · Computer Science 2017-11-17 Zhipeng Ding , Greg Fleishman , Xiao Yang , Paul Thompson , Roland Kwitt , Marc Niethammer

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

In this book chapter we study the Riemannian Geometry of the density registration problem: Given two densities (not necessarily probability densities) defined on a smooth finite dimensional manifold find a diffeomorphism which transforms…

Optimization and Control · Mathematics 2018-07-24 Martin Bauer , Sarang Joshi , Klas Modin

We present an approach to robustly track the geometry of an object that deforms over time from a set of input point clouds captured from a single viewpoint. The deformations we consider are caused by applying forces to known locations on…

Computer Vision and Pattern Recognition · Computer Science 2015-03-31 Stefanie Wuhrer , Jochen Lang , Motahareh Tekieh , Chang Shu

We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

Accurate tracking of an anatomical landmark over time has been of high interests for disease assessment such as minimally invasive surgery and tumor radiation therapy. Ultrasound imaging is a promising modality benefiting from low-cost and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Zhihua Liu , Bin Yang , Yan Shen , Xuejun Ni , Huiyu Zhou

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

High-fidelity biomechanical models usually involve the mechanical characterization of biological tissues using experimental methods based on optical measurements. In most experiments, strains are evaluated based on displacements of a few…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Ondřej Lisický , Stéphane Avril , Bastien Eydan , Baptiste Pierrat , Jiří Burša

We propose a PDE-constrained shape registration algorithm that captures the deformation and growth of biological tissue from imaging data. Shape registration is the process of evaluating optimum alignment between pairs of geometries through…

Biological Physics · Physics 2022-04-07 Aishwarya Pawar , Linlin Li , Arun K Gosain , David M Umulis , Adrian B Tepole

Deep learning-based deformable registration methods have been widely investigated in diverse medical applications. Learning-based deformable registration relies on weighted objective functions trading off registration accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Haoran Dou , Ning Bi , Luyi Han , Yuhao Huang , Ritse Mann , Xin Yang , Dong Ni , Nishant Ravikumar , Alejandro F. Frangi , Yunzhi Huang

In this article we study the problem of thoracic image registration, in particular the estimation of complex anatomical deformations associated with the breathing cycle. Using the intimate link between the Riemannian geometry of the space…

Numerical Analysis · Mathematics 2018-07-20 Caleb Rottman , Martin Bauer , Klas Modin , Sarang Joshi

Image registration is a fundamental task in medical image analysis. Recently, deep learning based image registration methods have been extensively investigated due to their excellent performance despite the ultra-fast computational time.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-14 Boah Kim , Dong Hwan Kim , Seong Ho Park , Jieun Kim , June-Goo Lee , Jong Chul Ye

Multimodal image registration is a challenging but essential step for numerous image-guided procedures. Most registration algorithms rely on the computation of complex, frequently non-differentiable similarity metrics to deal with the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Matteo Ronchetti , Wolfgang Wein , Nassir Navab , Oliver Zettinig , Raphael Prevost