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Most countries have started vaccinating people against COVID-19. However, due to limited production capacities and logistical challenges it will take months/years until herd immunity is achieved. Therefore, vaccination and social distancing…

Physics and Society · Physics 2021-04-22 Sara Grundel , Stefan Heyder , Thomas Hotz , Tobias K. S. Ritschel , Philipp Sauerteig , Karl Worthmann

We introduce an immunization method where the percentage of required vaccinations for immunity are close to the optimal value of a targeted immunization scheme of highest degree nodes. Our strategy retains the advantage of being purely…

Physics and Society · Physics 2009-11-13 Lazaros K. Gallos , Fredrik Liljeros , Panos Argyrakis , Armin Bunde , Shlomo Havlin

In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

Probability · Mathematics 2018-02-15 Carolina Fransson , Pieter Trapman

Nowadays, epidemic models provide an appropriate tool for describing the propagation of biological viruses in human or animal populations, or rumours and other kinds of information in social networks and malware in both computer and ad hoc…

Optimization and Control · Mathematics 2020-07-21 Vladislav Taynitskiy , Elena Gubar , Denis Fedyanin , Ilya Petrov , Quanyan Zhu

Often, vaccination programs are carried out based on self-interest rather than being mandatory. Owing to the perceptions about risks associated with vaccines and the `herd immunity' effect, it may provide suboptimal vaccination coverage for…

Physics and Society · Physics 2012-07-20 Hai-Feng Zhang , Zhi-Xi Wu , Xiao-Ke Xu , Michael Small , Bing-Hong Wang

In this paper, we investigate two major immunization strategies, random immunization and targeted immunization, of the susceptible-infected (SI) Model on the Barab\'{a}si-Albert (BA) networks. For the heterogenous structure, the random…

Biological Physics · Physics 2011-11-09 Wen-Jie Bai , Tao Zhou , Bing-Hong Wang

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Optimization and Control · Mathematics 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

Although community structure is ubiquitous in complex networks, few works exploit this topological property to control epidemics. In this work, devoted to networks with non-overlapping community structure (i.e, a node belongs to a single…

Social and Information Networks · Computer Science 2018-06-15 Zakariya Ghalmane , Mohammed El Hassouni , Hocine Cherifi

This study presents a mathematical model for optimal vaccination strategies in interconnected metropolitan areas, considering commuting patterns. It is a compartmental model with a vaccination rate for each city, acting as a control…

Populations and Evolution · Quantitative Biology 2024-04-29 Lucas Machado Moschen , María Soledad Aronna

Despite many studies on the transmission mechanism of the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it remains still challenging to efficiently reduce mortality. In this work, we apply a two-population…

Physics and Society · Physics 2021-09-14 Long Ma , Maksim Kitsak , Piet Van Mieghem

We study the interaction between epidemic spreading and a vaccination process. We assume that, similar to the disease spreading, also the vaccination process occurs through direct contact, i.e., it follows the standard…

Physics and Society · Physics 2020-06-22 Mozhgan Khanjanianpak , Nahid Azimi-Tafreshi , Claudio Castellano

We consider the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-metapopulation model (including SIS, SIR, SEIR,. . .), when the loss function is given by the effective reproduction number Re, which is defined…

Optimization and Control · Mathematics 2021-10-26 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

The way diseases spread through schools, epidemics through countries, and viruses through the Internet is crucial in determining their risk. Although each of these threats has its own characteristics, its underlying network determines the…

Physics and Society · Physics 2011-12-20 Christian M. Schneider , Tamara Mihaljev , Shlomo Havlin , Hans J. Herrmann

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

Populations and Evolution · Quantitative Biology 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

To understand the impact of vaccination, we consider a SIVR (susceptible-infected-vaccinated-recovered) model which combines impulsive vaccination into the classical SIR model. The final size is firstly defined and estimated, and then the…

Populations and Evolution · Quantitative Biology 2024-10-29 Phyu Phyu Win , Zhigui Lin , Mengyun Zhang

Vaccination has been proven to be the most effective method to prevent infectious diseases. However, there are still millions of children in low and middle-income countries who are not covered by routine vaccines and remain at risk. The…

Physics and Society · Physics 2021-04-30 Yuwen Yang , Hoda Bidkhori , Jayant Rajgopal

Vaccination has played an important role in preventing the spread of infectious diseases. However, the limited availability of vaccines and personnel at the roll-out of a new vaccine and the costs of vaccination campaigns often limit how…

Physics and Society · Physics 2026-01-27 Rowan Hoogervorst , Evelien van der Hurk , David Pisinger

Optimal curing strategy of suppressing competing epidemics spreading over complex networks is a critical issue. In this paper, we first establish a framework to capture the coupling between two epidemics, and then analyze the system's…

Systems and Control · Electrical Eng. & Systems 2021-04-22 Juntao Chen , Yunhan Huang , Rui Zhang , Quanyan Zhu

Background: Network-based interventions are most powerful against epidemics when the full network structure is known. However, resource constraints often require decisions based on partial network data. We investigated how the effectiveness…

Populations and Evolution · Quantitative Biology 2018-03-30 Yingrui Yang , Ashley McKhann , Guy Harling , Jukka-Pekka Onnela

In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple…

Optimization and Control · Mathematics 2021-12-17 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt