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Two recent topics on a formal thermodynamic analogy of intracellular diffusivity fluctuations observed experimentally in normal/anomalous diffusion are reported. Not only the analogs of the quantity of heat and work as well as the internal…

Statistical Mechanics · Physics 2026-04-22 Yuichi Itto

Recently, a formal analogy between the fluctuating diffusivity and thermodynamics has been proposed based on phenomena of heterogeneous diffusion observed in living cells. This not only offers the analogs of the quantity of heat and work as…

Statistical Mechanics · Physics 2025-09-16 Yuichi Itto

It has experimentally been found by Lampo et al. [Biophys. J. 112, 532 (2017)] that, for two different types of cell, the distribution of the diffusivities of RNA-protein particles over cytoplasm obeys an exponential law. Then, an…

Biological Physics · Physics 2019-08-02 Yuichi Itto

In this article we study the trapped motion of a molecule undergoing diffusivity fluctuations inside a harmonic potential. For the same diffusing-diffusivity process, we investigate two possible interpretations. Depending on whether…

Statistical Mechanics · Physics 2023-01-04 Yann Lanoiselée , Aleksander Stanislavsky , Davide Calebiro , Aleksander Weron

Many kinds of active particles, such as bacteria or active colloids, move in a thermostatted fluid by means of self-propulsion. Energy injected by such a non-equilibrium force is eventually dissipated as heat in the thermostat. Since…

Statistical Mechanics · Physics 2017-07-17 Andrea Puglisi , Umberto Marini Bettolo Marconi

A recent experiment [Sadoon AA, Wang Y. 2018 Phys. Rev. E 98, 042411] has revealed that nucleoid associated proteins (i.e., DNA-binding proteins) exhibit highly heterogeneous diffusion processes in bacteria where not only the diffusion…

Statistical Mechanics · Physics 2021-03-09 Yuichi Itto , Christian Beck

Using analytical calculations and computer simulations we consider both the lateral diffusion of a membrane protein and the fluctuation spectrum of the membrane in which the protein is embedded. The membrane protein interacts with the…

Soft Condensed Matter · Physics 2015-05-18 Ellen Reister-Gottfried , Stefan M. Leitenberger , Udo Seifert

The fluctuation spectrum of a quasi-spherical vesicle with active membrane proteins is calculated. The activity of the proteins is modeled as the proteins pushing on their surroundings giving rise to non-local force distributions. Both the…

Soft Condensed Matter · Physics 2009-11-11 Michael A. Lomholt

The effect of conformational fluctuations of modular macromolecules, such as enzymes, on their diffusion properties is addressed using a simple generic model of an asymmetric dumbbell made of two hydrodynamically coupled subunits. It is…

Soft Condensed Matter · Physics 2017-11-22 Pierre Illien , Tunrayo Adeleke-Larodo , Ramin Golestanian

A weak correlation between the diffusion-exponent fluctuations and the temperature fluctuations is discussed based on recent experimental observations for protein diffusion inside bacteria. Its existence is shown to be essential for…

Statistical Mechanics · Physics 2021-12-09 Yuichi Itto , Christian Beck

In the last ten years, a number of ``Conventional Fluctuation Theorems'' have been derived for systems with deterministic or stochastic dynamics, in a transient or in a non-equilibrium stationary state. These theorems gave explicit…

Statistical Mechanics · Physics 2007-05-23 R. van Zon , E. G. D. Cohen

We report the results of molecular dynamics simulations of the protein myosin carried out with an elastic network model. Quenching the system, we observe glassy behavior of a density correlation function and a density response function that…

Statistical Mechanics · Physics 2007-07-09 Kumiko Hayashi , Mitsunori Takano

The paper presents a unified approach to different fluctuation relations for classical nonequilibrium dynamics described by diffusion processes. Such relations compare the statistics of fluctuations of the entropy production or work in the…

Mathematical Physics · Physics 2009-11-13 Raphael Chetrite , Krzysztof Gawedzki

We demonstrate that the Gibbs-Shannon entropy is applicable to non-equilibrium systems of any size and boundary conditions. The change in microscopic entropy can be attributed to the stochastic nature of dynamic processes and to the…

Statistical Mechanics · Physics 2020-10-13 Jianzhong Wu

Relating thermodynamic and kinetic properties is a conceptual challenge with many practical benefits. Here, based on first principles, we derive a rigorous inequality relating the entropy and the dynamic propagator of particle…

Statistical Mechanics · Physics 2024-07-11 Benjamin Sorkin , Haim Diamant , Gil Ariel

The fluctuation-dissipation relation tells that dissipation always accompanies with thermal fluctuations. Relativistic fluctuating hydrodynamics is used to study the effects of the thermal fluctuations in the hydrodynamic expansion of the…

Nuclear Theory · Physics 2019-02-20 Tetsufumi Hirano , Ryuichi Kurita , Koichi Murase

We propose a generalization of stochastic thermodynamics to systems of active particles, which move under the combined influence of stochastic internal self-propulsions (activity) and a heat bath. The main idea is to consider joint…

Soft Condensed Matter · Physics 2019-11-20 Grzegorz Szamel

Measurements of lateral diffusion of proteins in a membrane typically assume that the movement of the protein occurs in a flat plane. Real membranes, however, are subject to thermal fluctuations, leading to movement of an inclusion into the…

Soft Condensed Matter · Physics 2007-05-23 E. Reister , U. Seifert

We report an experimental and theoretical analysis of the energy exchanged between two conductors kept at different temperature and coupled by the electric thermal noise. Experimentally we determine, as functions of the temperature…

Statistical Mechanics · Physics 2015-06-12 Sergio Ciliberto , Alberto Imparato , Antoine Naert , Marius Tanase

The fluctuation-dissipation relation (FDR) links thermal fluctuations and dissipation at thermal equilibrium through temperature. Extending it beyond equilibrium conditions in pursuit of broadening thermodynamics is often feasible, albeit…

Statistical Mechanics · Physics 2025-02-04 Dima Boriskovsky , Benjamin Lindner , Yael Roichman
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