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Motivated by the CATHGEN data, we develop a new statistical learning method for simultaneous variable selection and parameter estimation under the context of generalized partly linear models for data with high-dimensional covariates. The…

Methodology · Statistics 2023-11-02 Christian Chan , Xiaotian Dai , Thierry Chekouo , Quan Long , Xuewen Lu

Semi-competing risks data arise when both non-terminal and terminal events are considered in a model. Such data with multiple events of interest are frequently encountered in medical research and clinical trials. In this framework, terminal…

Methodology · Statistics 2022-11-21 Fatemeh Mahmoudi , Xuewen Lu

Competing risks data refer to situations where the occurrence of one event pre- cludes the possibility of other events happening, resulting in multiple mutually exclusive events. This data type is commonly encountered in medical research…

Methodology · Statistics 2025-10-21 Fatemeh Mahmoudi , Chenxi Li , Kaida Cai , Xuewen Lu

We introduce a novel method to simultaneously perform variable selection and estimation in the joint frailty model of recurrent and terminal events using the Broken Adaptive Ridge Regression penalty. The BAR penalty can be summarized as an…

Methodology · Statistics 2024-09-04 Christian Chan , Fatemeh Mahmoudi , Chel Hee Lee , Quan Long , Xuewen Lu

This paper develops two orthogonal contributions to scalable sparse regression for competing risks time-to-event data. First, we study and accelerate the broken adaptive ridge method (BAR), an $\ell_0$-based iteratively reweighted…

Methodology · Statistics 2021-11-30 Eric S. Kawaguchi , Jenny I. Shen , Marc A. Suchard , Gang Li

Penalized selection criteria like AIC or BIC are among the most popular methods for variable selection. Their theoretical properties have been studied intensively and are well understood, but making use of them in case of high-dimensional…

Methodology · Statistics 2016-04-27 Florian Frommlet , Gregory Nuel

In this paper we propose the Highly Adaptive Ridge (HAR): a regression method that achieves a $n^{-1/3}$ dimension-free L2 convergence rate in the class of right-continuous functions with square-integrable sectional derivatives. This is a…

Machine Learning · Statistics 2024-10-04 Alejandro Schuler , Alexander Hagemeister , Mark van der Laan

This paper develops a new scalable sparse Cox regression tool for sparse high-dimensional massive sample size (sHDMSS) survival data. The method is a local $L_0$-penalized Cox regression via repeatedly performing reweighted $L_2$-penalized…

Methodology · Statistics 2020-06-30 Eric S. Kawaguchi , Marc A. Suchard , Zhenqiu Liu , Gang Li

The accelerated failure time (AFT) models have proved useful in many contexts, though heavy censoring (as for example in cancer survival) and high dimensionality (as for example in microarray data) cause difficulties for model fitting and…

Methodology · Statistics 2013-12-10 Md Hasinur Rahaman Khan , J. Ewart H. Shaw

Popular parametric and semiparametric hazards regression models for clustered survival data are inappropriate and inadequate when the unknown effects of different covariates and clustering are complex. This calls for a flexible modeling…

Applications · Statistics 2021-03-16 Piyali Basak , Antonio R. Linero , Debajyoti SInha , Stuart Lipsitz

Penalization schemes like Lasso or ridge regression are routinely used to regress a response of interest on a high-dimensional set of potential predictors. Despite being decisive, the question of the relative strength of penalization is…

Methodology · Statistics 2018-11-08 Britta Velten , Wolfgang Huber

We propose an adaptive ridge (AR) estimation scheme for a heteroscedastic linear regression model with log-linear noise in data. We simultaneously estimate the mean and variance parameters, demonstrating new asymptotic distributional and…

Statistics Theory · Mathematics 2025-09-29 Ka Long Keith Ho , Hiroki Masuda

This paper introduces an assumption-lean method that constructs valid and efficient lower predictive bounds (LPBs) for survival times with censored data. We build on recent work by Cand\`es et al. (2021), whose approach first subsets the…

Methodology · Statistics 2023-11-08 Yu Gui , Rohan Hore , Zhimei Ren , Rina Foygel Barber

In many longitudinal studies, the covariate and response are often intermittently observed at irregular, mismatched and subject-specific times. How to deal with such data when covariate and response are observed asynchronously is an often…

Methodology · Statistics 2021-08-27 Hao Ran , Yang Bai

Ridge regression (RR) is a regularization technique that penalizes the L2-norm of the coefficients in linear regression. One of the challenges of using RR is the need to set a hyperparameter ($\alpha$) that controls the amount of…

Methodology · Statistics 2020-05-08 Ariel Rokem , Kendrick Kay

This article is concerned with the Bridge Regression, which is a special family in penalized regression with penalty function $\sum_{j=1}^{p}|\beta_j|^q$ with $q>0$, in a linear model with linear restrictions. The proposed restricted bridge…

Statistics Theory · Mathematics 2021-05-06 Bahadır Yüzbaşı , Mohammad Arashi , Fikri Akdeniz

Tree methods (recursive partitioning) are a popular class of nonparametric methods for analyzing data. One extension of the basic tree methodology is the survival tree, which applies recursive partitioning to censored survival data. There…

Methodology · Statistics 2017-03-01 Wei Fu , Jeffrey S. Simonoff

Survival analysis is complicated by censored data, high-dimensional features, and non-linear interactions. Classical models offer interpretability and superior calibration but are restricted to linear or predefined functional forms, while…

Machine Learning · Computer Science 2026-05-19 Mohammad Ashhad , Robert Hoehndorf , Ricardo Henao

Longitudinal data often involve heterogeneity, sparse signals, and contamination from response outliers or high-leverage observations especially in biomedical science. Existing methods usually address only part of this problem, either…

Methodology · Statistics 2026-02-26 Yuyao Wang , Yu Lu , Tianni Zhang , Mengfei Ran

Semiparametric accelerated failure time (AFT) models are a useful alternative to Cox proportional hazards models, especially when the assumption of constant hazard ratios is untenable. However, rank-based criteria for fitting AFT models are…

Methodology · Statistics 2022-01-20 Piotr M. Suder , Aaron J. Molstad
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