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Studies in recent years have demonstrated that neural organization and structure impact an individual's ability to perform a given task. Specifically, individuals with greater neural efficiency have been shown to outperform those with less…

Mapping the functional connectome has the potential to uncover key insights into brain organisation. However, existing workflows for functional connectomics are limited in their adaptability to new data, and principled workflow design is a…

Neurons and Cognition · Quantitative Biology 2022-06-02 Rastko Ciric , Armin W. Thomas , Oscar Esteban , Russell A. Poldrack

The increasing quantity and quality of the publicly available human cerebral diffusion MRI data make possible the study of the brain as it was unimaginable before. The Consensus Connectome Dynamics (CCD) is a remarkable phenomenon that was…

Neurons and Cognition · Quantitative Biology 2016-10-17 Balázs Szalkai , Vince Grolmusz

Cognitive flexibility describes the human ability to switch between modes of mental function to achieve goals. Mental switching is accompanied by transient changes in brain activity, which must occur atop an anatomical architecture that…

Neurons and Cognition · Quantitative Biology 2016-11-29 John D. Medaglia , Weiyu Huang , Elisabeth A. Karuza , Sharon L. Thompson-Schill , Alejandro Ribeiro , Danielle S. Bassett

Dynamic functional connectivity (dFC) derived from resting-state functional magnetic resonance imaging (fMRI) has been extensively utilized in brain science research. The sliding window correlation (SWC) method is a widely used approach for…

Neurons and Cognition · Quantitative Biology 2026-03-27 Jinlong Hu , Jiatong Huang , Zijian Cai

Understanding the dynamic nature of brain connectivity is critical for elucidating neural processing, behavior, and brain disorders. Traditional approaches such as sliding-window correlation (SWC) characterize time-varying undirected…

Neurons and Cognition · Quantitative Biology 2026-02-19 Nan Xu , Xiaodi Zhang , Wen-Ju Pan , Jeremy L. Smith , Eric H. Schumacher , Jason W. Allen , Vince D. Calhoun , Shella D. Keilholz

The question of controllability of natural and man-made network systems has recently received considerable attention. In the context of the human brain, the study of controllability may not only shed light into the organization and function…

Optimization and Control · Mathematics 2021-02-10 Tommaso Menara , Shi Gu , Danielle S. Bassett , Fabio Pasqualetti

The human connectome at the level of fiber tracts between brain regions has been shown to differ in patients with brain disorders compared to healthy control groups. Nonetheless, there is a potentially large number of different network…

Neurons and Cognition · Quantitative Biology 2013-10-16 Marcus Kaiser

Attention Deficit/Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders in children and is characterised by inattention, impulsiveness and hyperactivity. While several studies have analysed the static…

Neurons and Cognition · Quantitative Biology 2023-02-17 Rohit Misra , Tapan K. Gandhi

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Human brain development is a complex and dynamic process that is affected by several factors such as genetics, sex hormones, and environmental changes. A number of recent studies on brain development have examined functional connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Peyman Hosseinzadeh Kassani , Li Xiao , Gemeng Zhang , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu Ping Wang

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Motor skill acquisition in fields like surgery, robotics, and sports involves learning complex task sequences through extensive training. Traditional performance metrics, like execution time and error rates, offer limited insight as they…

Neurons and Cognition · Quantitative Biology 2025-02-21 Anil Kamat , Rahul Rahul , Lora Cavuoto , Harry Burke , Matthew Hackett , Jack Norfleet , Steven Schwaitzberg , Suvranu De

Functional connectivity (FC) between brain regions tracks symptom severity in many neuropsychiatric disorders. Transcranial magnetic stimulation (TMS) directly alters regional activity and indirectly alters FC. Predicting how FC will change…

Neurons and Cognition · Quantitative Biology 2022-08-25 Andrew C. Murphy , Romain Duprat , Theodore D. Satterthwaite , Desmond J. Oathes , Dani S. Bassett

The human brain displays rich communication dynamics that are thought to be particularly well-reflected in its marked community structure. Yet, the precise relationship between community structure in structural brain networks and the…

Neurons and Cognition · Quantitative Biology 2020-12-23 Shubhankar P. Patankar , Jason Z. Kim , Fabio Pasqualetti , Danielle S. Bassett

Individual differences in brain functional networks may be related to complex personal identifiers, including health, age, and ability. Understanding and quantifying these differences is a necessary first step towards developing predictive…

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial method for white matter (WM) parcellation to enable analysis of brains structural connectivity in health and disease. Current fiber clustering strategies primarily use…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Bocheng Guo , Jin Wang , Yijie Li , Junyi Wang , Mingyu Gao , Puming Feng , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

Physics and Society · Physics 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano
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