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One of the main aims in phylogenetics is the estimation of ancestral sequences based on present-day data like, for instance, DNA alignments. One way to estimate the data of the last common ancestor of a given set of species is to first…

Populations and Evolution · Quantitative Biology 2017-02-07 Lina Herbst , Mareike Fischer

Graphs are a powerful tool for analyzing large data sets, but many real-world phenomena involve interactions that go beyond the simple pairwise relationships captured by a graph. In this paper we introduce and study a simple combinatorial…

Data Structures and Algorithms · Computer Science 2025-11-25 Elise Tate , Joshua A. Grochow

Stochastic models of evolution (Markov random fields on trivalent trees) generally assume that different characters (different runs of the stochastic process) are independent and identically distributed. In this paper we take the first…

Populations and Evolution · Quantitative Biology 2014-10-28 Deeparnab Chakrabarty , Sampath Kannan , Kevin Tian

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

Machine Learning · Computer Science 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

Data-Oriented Parsing (dop) ranks among the best parsing schemes, pairing state-of-the art parsing accuracy to the psycholinguistic insight that larger chunks of syntactic structures are relevant grammatical and probabilistic units. Parsing…

Computation and Language · Computer Science 2007-05-23 Guy De Pauw

We consider the well-studied pattern counting problem: given a permutation $\pi \in \mathbb{S}_n$ and an integer $k > 1$, count the number of order-isomorphic occurrences of every pattern $\tau \in \mathbb{S}_k$ in $\pi$. Our first result…

Data Structures and Algorithms · Computer Science 2024-07-09 Gal Beniamini , Nir Lavee

Large Language Models (LLMs) tend to respond correctly to prompts that align well with the data they were trained and fine-tuned on. Yet, small shifts in wording, format, or language can trigger surprisingly large failures, especially on…

Machine Learning · Computer Science 2026-05-12 Yeping Jin , Jiaming Hu , Ioannis Ch. Paschalidis

Motivation: Millions of genes in the modern species belong to only thousands of `gene families'. A gene family includes instances of the same gene in different species (orthologs) and duplicate genes in the same species (paralogs). Genes…

Populations and Evolution · Quantitative Biology 2012-05-04 Yu Zheng , Taoyang Wu , Louxin Zhang

Discovering evolutionary traits that are heritable across species on the tree of life (also referred to as a phylogenetic tree) is of great interest to biologists to understand how organisms diversify and evolve. However, the measurement of…

The statistical estimation of phylogenies is always associated with uncertainty, and accommodating this uncertainty is an important component of modern phylogenetic comparative analysis. The birth-death polytomy resolver is a method of…

Quantitative Methods · Quantitative Biology 2015-03-18 Daniel L. Rabosky

Tree-child networks are a recently-described class of directed acyclic graphs that have risen to prominence in phylogenetics (the study of evolutionary trees and networks). Although these networks have a number of attractive mathematical…

Probability · Mathematics 2023-01-10 François Bienvenu , Amaury Lambert , Mike Steel

We use a combination of analytic models and computer simulations to gain insight into the dynamics of evolution. Our results suggest that certain interesting phenomena should eventually emerge from the fossil record. For example, there…

Populations and Evolution · Quantitative Biology 2007-05-23 Stuart Samuel , Gezhi Weng

More than ever, today we are left with the abundance of molecular data outpaced by the advancements of the phylogenomic methods. Especially in the case of presence of many genes over a set of species under the phylogeny question, more…

Applications · Statistics 2021-11-29 Ali Amiryousefi

The classical pattern matching asks for locating all occurrences of one string, called the pattern, in another, called the text, where a string is simply a sequence of characters. Due to the potential practical applications, it is desirable…

Data Structures and Algorithms · Computer Science 2024-10-30 Jonas Ellert , Paweł Gawrychowski , Adam Górkiewicz , Tatiana Starikovskaya

Each gene has its own evolutionary history which can substantially differ from the evolutionary histories of other genes. For example, some individual genes or operons can be affected by specific horizontal gene transfer and recombination…

Populations and Evolution · Quantitative Biology 2022-05-26 Nadia Tahiri , Bernard Fichet , Vladimir Makarenkov

Finding the longest common subsequence in $k$-length substrings (LCS$k$) is a recently proposed problem motivated by computational biology. This is a generalization of the well-known LCS problem in which matching symbols from two sequences…

Data Structures and Algorithms · Computer Science 2013-11-20 Sebastian Deorowicz , Szymon Grabowski

In comparison to phylogenetic trees, phylogenetic networks are more suitable to represent complex evolutionary histories of species whose past includes reticulation such as hybridisation or lateral gene transfer. However, the reconstruction…

Populations and Evolution · Quantitative Biology 2024-05-31 Janosch Döcker , Simone Linz , Kristina Wicke

Survival analysis concerns the task of predicting the time until an event occurs. Often used in the medical field, survival analysis deals with incomplete (i.e., censored) data, for instance, from patients who did not experience the event…

Machine Learning · Computer Science 2026-05-29 Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

We describe the conditions under which a set of continuous variables or characters can be described as an X-tree or a split network. A distance matrix corresponds exactly to a split network or a valued X-tree if, after ordering of the taxa,…

Quantitative Methods · Quantitative Biology 2009-06-11 Marc Thuillard , Didier Fraix-Burnet

Large Language Models (LLMs) often struggle to maintain their original performance when faced with semantically coherent but task-irrelevant contextual information. Although prior studies have explored this issue using fixed-template or…

Computation and Language · Computer Science 2025-09-23 Yanbo Wang , Zixiang Xu , Yue Huang , Chujie Gao , Siyuan Wu , Jiayi Ye , Pin-Yu Chen , Xiuying Chen , Xiangliang Zhang