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Membranes consist of pores and the walls of these pores are often charged. In contact with an aqueous solution, the pores fill with water and ions migrate from solution into the pores until chemical equilibrium is reached. The distribution…

Chemical Physics · Physics 2024-03-06 R. Wang , M. Elimelech , P. M. Biesheuvel

We discuss multiscale simulations of long biopolymer translocation through wide nanopores that can accommodate multiple polymer strands. The simulations provide clear evidence of folding quantization, namely, the translocation proceeds…

Biological Physics · Physics 2009-11-13 Simone Melchionna , Massimo Bernaschi , Maria Fyta , Efthimios Kaxiras , Sauro Succi

This work exploits the zeptoliter sensing volume of electrolyte-filled nanopores to determine, simultaneously and in real time, the approximate shape, volume, charge, rotational diffusion coefficient, and dipole moment of individual…

Mechanically interlocked molecules have marked a breakthrough in the field of topological chemistry and boosted the vigorous development of molecular machinery. As an archetypal example of the interlocked molecules, catenanes comprise…

Biological Physics · Physics 2021-05-03 Andreas Peil , Pengfei Zhan , Na Liu

Bipolar nanofluidic diode is based on nanopore with positive and negative surface charges separated by a junction. This paper investigates the effects of the pore structure, taking the bullet-like pore as an example, on the ion current…

Soft Condensed Matter · Physics 2013-09-11 Li-Jian Qu , Xinghua Zhang , Jie Fua , Lin Li , Dadong Yan

Nanofabrication techniques for achieving dimensional control at the nanometer scale are generally equipment-intensive and time-consuming. The use of energetic beams of electrons or ions has placed the fabrication of nanopores in thin…

Mesoscale and Nanoscale Physics · Physics 2014-03-25 Harold Kwok , Kyle Briggs , Vincent Tabard-Cossa

To bridge the gap between the sequences and 3-dimensional (3D) structures of RNAs, some computational models have been proposed for predicting RNA 3D structures. However, the existed models seldom consider the conditions departing from the…

Biological Physics · Physics 2014-09-12 Ya-Zhou Shi , Feng-Hua Wang , Yuan-Yan Wu , Zhi-Jie Tan

Fundamental understanding of ionic transport at the nanoscale is essential for developing biosensors based on nanopore technology and new generation high-performance nanofiltration membranes for separation and purification applications. We…

We present a unified model of compound semiconductor growth based on kinetic Monte Carlo simulations in tandem with new experimental results that can describe and predict the mechanisms for the formation of various types of nanostructures…

Continuum simulation is employed to study ion transport and fluid flow through a nanopore in a solid-state membrane under an applied potential drop. Results show the existence of concentration polarization layers on the surfaces of the…

Fluid Dynamics · Physics 2015-06-16 Mao Mao , Sandip Ghosal , Guohui Hu

Long range charge transfer experiments in DNA oligomers and the subsequently measured -- and very diverse -- transport response of DNA wires in solid state experiments exemplifies the need for a thorough theoretical understanding of charge…

Genomics · Quantitative Biology 2015-05-13 G. Cuniberti , E. Macia , A. Rodriguez , R. A. Römer

We study the electric properties of single-stranded DNA molecules with hairpin-like shapes in the presence of a magnetic flux. It is shown that the current amplitude can be modulated by the applied field. The details of the electric…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Juyeon Yi , Henri Orland

The folding of biological macromolecules is a fundamental process of which we lack a full comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also folds, at physiological salt conditions, by forming non-specific…

Soft Condensed Matter · Physics 2021-09-23 X. Viader Godoy , C. R. Pulido , B. Ibarra , M. Manosas , F. Ritort

Various experimental settings that involve drying solutions or suspensions of nanoparticles -- often called nanofluids -- have recently been used to produce structured nanoparticle layers. In addition to the formation of polygonal networks…

Soft Condensed Matter · Physics 2013-03-25 I. Vancea , U. Thiele , E. Pauliac-Vaujour , A. Stannard , C. P. Martin , M. O. Blunt , P. J. Moriarty

In recent years significant attention has been attracted to proposals which utilize DNA for nanotechnological applications. Potential applications of these ideas range from the programmable self-assembly of colloidal crystals, to biosensors…

Soft Condensed Matter · Physics 2008-05-02 Nicholas A. Licata

We propose using graphene electrodes with hydrogenated edges for solid-state nanopore-based DNA sequencing, and perform molecular dynamics simulations in conjunction with electronic transport calculations to explore the potential merits of…

Biological Physics · Physics 2011-08-03 Yuhui He , Ralph H. Scheicher , Anton Grigoriev , Rajeev Ahuja , Shibing Long , ZongLiang Huo , Ming Liu

Modeling the ion concentration profile in nanochannel plays an important role in understanding the electrical double layer and electroosmotic flow. Due to the non-negligible surface interaction and the effect of discrete solvent molecules,…

Machine Learning · Computer Science 2023-12-19 Zhonglin Cao , Yuyang Wang , Cooper Lorsung , Amir Barati Farimani

Solid-state nanopores offer a powerful platform for nanoscale analysis of individual analytes, including biomolecules and functionalized nanoparticles, by confining them within a precisely defined sensing region. However, their inherently…

Bond-orientational order in DNA-assembled nanoparticle lattices is explored with the help of recently introduced Symmetry-specific Bond Order Parameters (SymBOPs). This approach provides a more sensitive analysis of local order than…

Soft Condensed Matter · Physics 2023-09-29 Jack A. Logan , Aaron Michelson , Ajith Pattammattel , Hanfei Yan , Oleg Gang , Alexei V. Tkachenko

We propose a dynamical model for the secondary structure of DNA, which is based on the finite stacking enthalpies used in thermodynamics calculations. In this model, the two strands can separate and the bases are allowed to rotate…

Biological Physics · Physics 2016-08-16 Sahin Buyukdagli , Michaël Sanrey , Marc Joyeux