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Brightfield and fluorescent imaging of whole brain sections are funda- mental tools of research in mouse brain study. As sectioning and imaging become more efficient, there is an increasing need to automate the post-processing of sec- tions…

Computer Vision and Pattern Recognition · Computer Science 2018-03-12 Yuncong Chen , David Kleinfeld , Martyn Goulding , Yoav Freund

While supervised learning has enabled great progress in many applications, unsupervised learning has not seen such widespread adoption, and remains an important and challenging endeavor for artificial intelligence. In this work, we propose…

Machine Learning · Computer Science 2019-01-23 Aaron van den Oord , Yazhe Li , Oriol Vinyals

Neuroimaging-based prediction of neurocognitive measures is valuable for studying how the brain's structure relates to cognitive function. However, the accuracy of prediction using popular linear regression models is relatively low. We…

Contrastive Learning has shown impressive results on natural and medical images, without requiring annotated data. However, a particularity of medical images is the availability of meta-data (such as age or sex) that can be exploited for…

Machine Learning · Computer Science 2021-11-11 Benoit Dufumier , Pietro Gori , Julie Victor , Antoine Grigis , Edouard Duchesnay

Deep clustering has shown its promising capability in joint representation learning and clustering via deep neural networks. Despite the significant progress, the existing deep clustering works mostly utilize some distribution-based…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Yuankun Xu , Dong Huang , Chang-Dong Wang , Jian-Huang Lai

Contrastive learning is a family of self-supervised methods where a model is trained to solve a classification task constructed from unlabeled data. It has recently emerged as one of the leading learning paradigms in the absence of labels…

Machine Learning · Statistics 2021-03-05 Bingbin Liu , Pradeep Ravikumar , Andrej Risteski

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

The popularity of self-supervised learning has made it possible to train models without relying on labeled data, which saves expensive annotation costs. However, most existing self-supervised contrastive learning methods often overlook the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Weiquan Li , Xianzhong Long , Yun Li

We develop an approach to learning visual representations that embraces multimodal data, driven by a combination of intra- and inter-modal similarity preservation objectives. Unlike existing visual pre-training methods, which solve a proxy…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Xin Yuan , Zhe Lin , Jason Kuen , Jianming Zhang , Yilin Wang , Michael Maire , Ajinkya Kale , Baldo Faieta

Learning new information without forgetting prior knowledge is central to human intelligence. In contrast, neural network models suffer from catastrophic forgetting: a significant degradation in performance on previously learned tasks when…

Machine Learning · Computer Science 2025-07-16 James P Jun , Vijay Marupudi , Raj Sanjay Shah , Sashank Varma

Learning and interpreting the structure of the environment is an innate feature of biological systems, and is integral to guiding flexible behaviours for evolutionary viability. The concept of a cognitive map has emerged as one of the…

Neurons and Cognition · Quantitative Biology 2022-02-04 James C. R. Whittington , David McCaffary , Jacob J. W. Bakermans , Timothy E. J. Behrens

Machine unlearning aims to eliminate the influence of a subset of training samples (i.e., unlearning samples) from a trained model. Effectively and efficiently removing the unlearning samples without negatively impacting the overall model…

Machine Learning · Computer Science 2024-01-22 Hong kyu Lee , Qiuchen Zhang , Carl Yang , Jian Lou , Li Xiong

Contrastive learning has gained popularity due to its robustness with good feature representation performance. However, cosine distance, the commonly used similarity metric in contrastive learning, is not well suited to represent the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Jing Wei Tan , Won-Ki Jeong

Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Yundi Zhang , Chen Chen , Suprosanna Shit , Sophie Starck , Daniel Rueckert , Jiazhen Pan

Continual learning aims to learn new tasks without forgetting previously learned ones. We hypothesize that representations learned to solve each task in a sequence have a shared structure while containing some task-specific properties. We…

Machine Learning · Computer Science 2020-07-22 Sayna Ebrahimi , Franziska Meier , Roberto Calandra , Trevor Darrell , Marcus Rohrbach

Contrastive learning, along with its variations, has been a highly effective self-supervised learning method across diverse domains. Contrastive learning measures the distance between representations using cosine similarity and uses…

Machine Learning · Computer Science 2023-10-11 Daniel Rho , TaeSoo Kim , Sooill Park , Jaehyun Park , JaeHan Park

Deep learning for medical imaging suffers from temporal and privacy-related restrictions on data availability. To still obtain viable models, continual learning aims to train in sequential order, as and when data is available. The main…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Marius Memmel , Camila Gonzalez , Anirban Mukhopadhyay

Contrastive learning produces coherent semantic feature embeddings by encouraging positive samples to cluster closely while separating negative samples. However, existing contrastive learning methods lack principled guarantees on coverage…

Machine Learning · Computer Science 2026-03-30 Yahya Alkhatib , Wee Peng Tay

Preserving maximal information is one of principles of designing self-supervised learning methodologies. To reach this goal, contrastive learning adopts an implicit way which is contrasting image pairs. However, we believe it is not fully…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Hong-Yu Zhou , Chixiang Lu , Sibei Yang , Xiaoguang Han , Yizhou Yu

In response to an object presentation, supervised learning schemes generally respond with a parsimonious label. Upon a similar presentation we humans respond again with a label, but are flooded, in addition, by a myriad of associations. A…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Daniel N. Nissani