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Asynchrony, overlaps and delays in sensory-motor signals introduce ambiguity as to which stimuli, actions, and rewards are causally related. Only the repetition of reward episodes helps distinguish true cause-effect relationships from…

Neural and Evolutionary Computing · Computer Science 2014-09-10 Andrea Soltoggio

This paper explores the connection between two recently identified phenomena in deep learning: plasticity loss and neural collapse. We analyze their correlation in different scenarios, revealing a significant association during the initial…

Machine Learning · Computer Science 2024-04-04 Guglielmo Bonifazi , Iason Chalas , Gian Hess , Jakub Łucki

Recent experiments of imbibition in columnar geometries show interfacial fluctuations whose dynamic scaling is not compatible with the usual non local model governed by surface tension that results from a macroscopic description. To explore…

Statistical Mechanics · Physics 2009-11-13 M. Pradas , A. Hernández-Machado , M. A. Rodríguez

We present a fiber-distributed model of the reinforcing collagen of the human cornea. The model describes the basic connections between the components of the tissue by defining an elementary block (cell) and upscaling it to the physical…

Biological Physics · Physics 2023-06-28 Maria Laura De Bellis , Marcello Vasta , Alessio Gizzi , Anna Pandolfi

We propose an ultrasound approach which provides, with one single examination and one single device, access to three bone biomarkers: anatomy, tissue quality and blood flow. It unlocks ultrasound imaging inside bone by accounting for…

The cerebellum and cerebral cortex form tightly coupled circuits thought to support flexible and efficient temporal processing. How this interaction shapes cortical learning dynamics, and whether such heterogeneous modularity can benefit…

Neurons and Cognition · Quantitative Biology 2026-05-12 Alexandra Voce , Emmanouil Giannakakis , Claudia Clopath

Tendrils coil their shape to anchor the plant to supporting structures, allowing vertical growth toward light. Although climbing plants have been studied for a long time, extracting information regarding the relationship between the…

Robotics · Computer Science 2025-11-18 Jie Fan , Francesco Visentin , Barbara Mazzolai , Emanuela Del Dottore

Recent advances in foundation models have led to a promising trend of developing large recommendation models to leverage vast amounts of available data. Still, mainstream models remain embarrassingly small in size and na\"ive enlarging does…

Machine Learning · Computer Science 2024-06-07 Xingzhuo Guo , Junwei Pan , Ximei Wang , Baixu Chen , Jie Jiang , Mingsheng Long

Coordinated cellular movements are key processes in tissue morphogenesis. Using a cell-based modeling approach we study the dynamics of epithelial layers lining surfaces with constant and varying curvature. We demonstrate that extrinsic…

Soft Condensed Matter · Physics 2024-03-21 Lea Happel , Axel Voigt

We propose a simple model for scaffold aided bone regeneration. In this model, only macroscopic quantities, e.g., locally averaged osteoblast densities, are considered. This allows for use of this model in an optimization algorithm, whose…

Tissues and Organs · Quantitative Biology 2021-10-15 Patrick Dondl , Marius Zeinhofer

Computer modelling for evolutionary systems consists in: 1) to store in the memory the individual features of each member of a large population; and 2) to update the whole system repeatedly, as time goes by, according to some prescribed…

Statistical Mechanics · Physics 2007-05-23 Paulo Murilo Castro de Oliveira

The transformation of the regular vasculature in normal tissue into a highly inhomogeneous tumor specific capillary network is described by a theoretical model incorporating tumor growth, vessel cooption, neo-vascularization, vessel…

Tissues and Organs · Quantitative Biology 2016-09-08 K. Bartha , H. Rieger

The purpose of this study was to report numerical validation of a 3D finite element model of contracting muscle. The model was based on continuum theory for fibre-reinforced composite materials. Here we simulated contractions for an…

Quantitative Methods · Quantitative Biology 2015-04-03 Hadi Rahemi , Nilima Nigam , James M. Wakeling

The role of porous structure and glass density in response to compressive deformation of amorphous materials is investigated via molecular dynamics simulations. The disordered, porous structures were prepared by quenching a high-temperature…

Soft Condensed Matter · Physics 2018-09-18 Nikolai V. Priezjev , Maxim A. Makeev

We present simulations of granular flows in a modified Couette cell, using a continuum model recently proposed for dense granular flows. Based on a friction coefficient, which depends on an inertial number, the model captures the positions…

Soft Condensed Matter · Physics 2009-11-13 Pierre Jop

A continuum mechanical model of coupled dislocation based plasticity and fracture at finite deformation is proposed. Motivating questions and target applications of the model are sketched.

Materials Science · Physics 2024-04-04 Amit Acharya

Using computer simulations, we identify the mechanisms causing aggregation and structural arrest of colloidal suspensions interacting with a short-ranged attraction at moderate and high densities. Two different non-ergodicity transitions…

Condensed Matter · Physics 2009-11-07 Antonio M. Puertas , Matthias Fuchs , Michael E. Cates

To accelerate the development of strategies for cartilage tissue engineering, models are necessary to study the interactions between cellular dynamics and scaffold (SC) porosity. In experiments, cells are seeded in a porous SC where over a…

Tissues and Organs · Quantitative Biology 2018-09-03 Simone Cassani , Sarah D. Olson

Cochlea displays complex and highly nonlinear behavior in response to wide-ranging auditory stimuli. While there have been many recent advancements in the modeling of cochlear dynamics, it remains unclear what mathematical structures…

Biological Physics · Physics 2018-08-07 Keith Hayton , Dimitrios Moirogiannis , Marcelo Magnasco

We study the dynamics of a seeding experiment where a fibrous scaffold material is colonized by two types of cell populations. The specific application that we have in mind is related to the idea of meniscus tissue regeneration. In order to…