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The prediction of tumor progression and chemotherapy response has been recently tackled exploiting Tumor Infiltrating Lymphocytes (TILs) and the nuclear protein Ki67 as prognostic factors. Recently, deep neural networks (DNNs) have been…

Quantitative Methods · Quantitative Biology 2024-01-02 J. Gliozzo , G. Marinò , A. Bonometti , M. Frasca , D. Malchiodi

In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Francisco Javier Díaz-Pernas , Mario Martínez-Zarzuela , Míriam Antón-Rodríguez , David González-Ortega

Brain tumor is one of the leading causes of cancer death. The high-grade brain tumors are easier to recurrent even after standard treatment. Therefore, developing a method to predict brain tumor recurrence location plays an important role…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Tongxue Zhou , Alexandra Noeuveglise , Romain Modzelewski , Fethi Ghazouani , Sébastien Thureau , Maxime Fontanilles , Su Ruan

We provide in this paper a comprehensive comparison of various transfer learning strategies and deep learning architectures for computer-aided classification of adult-type diffuse gliomas. We evaluate the generalizability of out-of-domain…

Automatically segmenting sub-regions of gliomas (necrosis, edema and enhancing tumor) and accurately predicting overall survival (OS) time from multimodal MRI sequences have important clinical significance in diagnosis, prognosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-17 Xiaoqing Guo , Chen Yang , Pak Lun Lam , Peter Y. M. Woo , Yixuan Yuan

Deep learning (DL) powered biomedical ultrasound imaging is an emerging research field where researchers adapt the image analysis capabilities of DL algorithms to biomedical ultrasound imaging settings. A major roadblock to wider adoption…

Image and Video Processing · Electrical Eng. & Systems 2023-01-16 Ufuk Soylu , Michael L. Oelze

Lung cancer is the leading cause of cancer deaths. Early detection through low-dose computed tomography (CT) screening has been shown to significantly reduce mortality but suffers from a high false positive rate that leads to unnecessary…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Jason L. Causey , Yuanfang Guan , Wei Dong , Karl Walker , Jake A. Qualls , Fred Prior , Xiuzhen Huang

In computational pathology, cancer grading has been mainly studied as a categorical classification problem, which does not utilize the ordering nature of cancer grades such as the higher the grade is, the worse the cancer is. To incorporate…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Ju Cheon Lee , Keunho Byeon , Boram Song , Kyungeun Kim , Jin Tae Kwak

Reaction-diffusion models have been proposed for decades to capture the growth of gliomas, the most common primary brain tumours. However, severe limitations regarding the estimation of the initial conditions and parameter values of such…

Computer-aided detection or decision support systems aim to improve breast cancer screening programs by helping radiologists to evaluate digital mammography (DM) exams. Commonly such methods proceed in two steps: selection of candidate…

Computer Vision and Pattern Recognition · Computer Science 2018-03-09 Timothy de Moor , Alejandro Rodriguez-Ruiz , Albert Gubern Mérida , Ritse Mann , Jonas Teuwen

This study focuses on automatic skin cancer detection using a Meta-learning approach for dermoscopic images. The aim of this study is to explore the benefits of the generalization of the knowledge extracted from non-medical data in the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Sara I. Garcia

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

In the clinical diagnosis and treatment of brain tumors, manual image reading consumes a lot of energy and time. In recent years, the automatic tumor classification technology based on deep learning has entered people's field of vision.…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Yuhao Zhang , Shuhang Wang , Haoxiang Wu , Kejia Hu , Shufan Ji

In post-operative radiotherapy for prostate cancer, the cancerous prostate gland has been surgically removed, so the clinical target volume (CTV) to be irradiated encompasses the microscopic spread of tumor cells, which cannot be visualized…

Atom-probe tomography (APT) facilitates nano- and atomic-scale characterization and analysis of microstructural features. Specifically, APT is well suited to study the interfacial properties of granular or heterophase systems.…

Features learned from single radiologic images are unable to provide information about whether and how much a lesion may be changing over time. Time-dependent features computed from repeated images can capture those changes and help…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Thomas Z. Li , Kaiwen Xu , Riqiang Gao , Yucheng Tang , Thomas A. Lasko , Fabien Maldonado , Kim Sandler , Bennett A. Landman

We present a novel deep learning framework that uses dynamic functional connectivity to simultaneously localize the language and motor areas of the eloquent cortex in brain tumor patients. Our method leverages convolutional layers to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-18 Naresh Nandakumar , Niharika Shimona D'souza , Komal Manzoor , Jay J. Pillai , Sachin K. Gujar , Haris I. Sair , Archana Venkataraman

Test-time adaptation (TTA) has increasingly been an important topic to efficiently tackle the cross-domain distribution shift at test time for medical images from different institutions. Previous TTA methods have a common limitation of…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Hongzheng Yang , Cheng Chen , Meirui Jiang , Quande Liu , Jianfeng Cao , Pheng Ann Heng , Qi Dou

Accurate and automatic analysis of breast MRI plays an important role in early diagnosis and successful treatment planning for breast cancer. Due to the heterogeneity nature, accurate diagnosis of tumors remains a challenging task. In this…

Image and Video Processing · Electrical Eng. & Systems 2019-06-10 Luyang Luo , Hao Chen , Xi Wang , Qi Dou , Huangjin Lin , Juan Zhou , Gongjie Li , Pheng-Ann Heng

Conventional radiotherapy dose calculation algorithms are often computationally slow and non-differentiable, creating bottlenecks for online adaptive radiotherapy (ART) and limiting end-to-end automatic planning. Deep learning provides…