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Monte Carlo (MC) simulations provide gold-standard accuracy for carbon ion therapy dose calculations but are computationally intensive. Analytical pencil beam algorithms offer speed but reduced accuracy in heterogeneous tissues. We…

Positron emission tomography (PET) scans expose patients to radiation, which can be mitigated by reducing the dose, albeit at the cost of diminished quality. This makes low-dose (LD) PET recovery an active research area. Previous studies…

Image and Video Processing · Electrical Eng. & Systems 2026-03-11 Ghulam Nabi Ahmad Hassan Yar , Himashi Peiris , Victoria Mar , Cameron Dennis Pain , Zhaolin Chen

A key step in Adaptive Radiation Therapy (ART) workflows is the evaluation of the patient's anatomy at treatment time to ensure the accuracy of the delivery. To this end, Cone Beam Computerized Tomography (CBCT) is widely used being…

Image and Video Processing · Electrical Eng. & Systems 2025-02-10 Ricardo Coimbra Brioso , Leonardo Crespi , Andrea Seghetto , Damiano Dei , Nicola Lambri , Pietro Mancosu , Marta Scorsetti , Daniele Loiacono

Imaging with multiple modalities or multiple channels is becoming increasingly important for our modern society. A key tool for understanding and early diagnosis of cancer and dementia is PET-MR, a combined positron emission tomography and…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Matthias J. Ehrhardt

In the field of non-invasive medical imaging, radiomic features are utilized to measure tumor characteristics. However, these features can be affected by the techniques used to discretize the images, ultimately impacting the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-06 Wenhao Chi , Haiping Liu , Hongqiao Dong , Wenhua Liang , Bo Liu

Self-supervised learning has proven to be invaluable in making best use of all of the available data in biomedical image segmentation. One particularly simple and effective mechanism to achieve self-supervision is inpainting, the task of…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Subhradeep Kayal , Shuai Chen , Marleen de Bruijne

Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, particularly in routine physical examinations where chest CT scans are…

Medical Physics · Physics 2025-04-10 Zirui Ye , Bei Yao , Haoran Zheng , Li Tao , Ripeng Wang , Yankui Chang , Zhi Chen , Yingming Zhao , Wei Wei , Xie George Xu

Recent advances in high-resolution biomedical imaging focusing on morphological, electrical, and biochemical properties of cells and tissues, scaling from cell clusters down to the molecular level, have improved cancer diagnosis. Multiscale…

Medical Physics · Physics 2023-04-21 Phat K. Huynh , Dang Nguyen , Grace Binder , Sharad Ambardar , Trung Q. Le , Dmitri V. Voronine

Quantitative Magnetic Resonance Imaging (MRI) is based on a two-steps approach: estimation of the magnetic moments distribution inside the body, followed by a voxel-by-voxel quantification of the human tissue properties. This splitting…

Transcranial magnetic stimulation (TMS) is a technique for noninvasively stimulating a brain area for therapeutic, rehabilitation treatments and neuroscience research. Despite our understanding of the physical principles and experimental…

Neurons and Cognition · Quantitative Biology 2020-12-30 Jose Gomez-Tames , Ilkka Laakso , Akimasa Hirata

Positron Emission Tomography (PET) and Computed Tomography (CT) are essential for diagnosing, staging, and monitoring various diseases, particularly cancer. Despite their importance, the use of PET/CT systems is limited by the necessity for…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Dac Thai Nguyen , Trung Thanh Nguyen , Huu Tien Nguyen , Thanh Trung Nguyen , Huy Hieu Pham , Thanh Hung Nguyen , Thao Nguyen Truong , Phi Le Nguyen

The task of radiology reporting comprises describing and interpreting the medical findings in radiographic images, including description of their location and appearance. Automated approaches to radiology reporting require the image to be…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Francesco Dalla Serra , Chaoyang Wang , Fani Deligianni , Jeffrey Dalton , Alison Q. O'Neil

Background and Purpose: Increasing the number of arcs in volumetric modulated arc therapy (VMAT) allows for better intensity modulation and may improve plan quality. However, this leads to longer delivery times, which may cause patient…

Medical Physics · Physics 2025-10-31 Nathan Torelli , Madalyne Day , Jan Unkelbach

Image reconstruction for positron emission tomography (PET) is challenging because of the ill-conditioned tomographic problem and low counting statistics. Kernel methods address this challenge by using kernel representation to incorporate…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Siqi Li , Guobao Wang

Deep neural networks have received considerable attention in clinical imaging, particularly with respect to the reduction of radiation risk. Lowering the radiation dose by reducing the photon flux inevitably results in the degradation of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Khalid L. Alsamadony , Ertugrul U. Yildirim , Guenther Glatz , Umair bin Waheed , Sherif M. Hanafy

With pervasive applications of medical imaging in health-care, biomedical image segmentation plays a central role in quantitative analysis, clinical diagno- sis, and medical intervention. Since manual anno- tation su ers limited…

Computer Vision and Pattern Recognition · Computer Science 2018-03-14 Xiaowei Xu , Qing Lu , Yu Hu , Lin Yang , Sharon Hu , Danny Chen , Yiyu Shi

Background: Tumour budding is an independent predictor of metastasis and prognosis in colorectal cancer and is a vital part of the pathology specification report. In a conventional pathological section observation process, pathologists have…

Medical Physics · Physics 2025-03-21 Yiyan Su , Ruiqing Sun , Yajing Wang , Yanfeng xi , Shaohui Zhang

Doctors and researchers routinely use diffusion tensor imaging (DTI) and tractography to visualize the fibrous structure of tissues in the human body. This paper explores the connection of these techniques to the painterly rendering of…

Graphics · Computer Science 2025-11-04 Alberto Di Biase

Cervical cancer presents a significant global health challenge, necessitating advanced diagnostic and prognostic approaches for effective treatment. This paper investigates the potential of employing multi-modal medical imaging at various…

Medical Physics · Physics 2024-08-27 Haotian Feng , Emi Yoshida , Ke Sheng

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang