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Problem definition: Access to accurate predictions of patients' outcomes can enhance medical staff's decision-making, which ultimately benefits all stakeholders in the hospitals. A large hospital network in the US has been collaborating…

Predictive algorithms inform consequential decisions in settings with selective labels: outcomes are observed only for units selected by past decision makers. This creates an identification problem under unobserved confounding -- when…

Econometrics · Economics 2025-11-07 Ashesh Rambachan , Amanda Coston , Edward Kennedy

Large language models (LLMs) are increasingly deployed in decision-support systems for high-stakes domains such as hiring and university admissions, where choices often involve selecting among competing alternatives. While prior work has…

Artificial Intelligence · Computer Science 2026-04-15 Haonan Yin , Shai Vardi , Vidyanand Choudhary

A multitude of classifiers can be trained on the same data to achieve similar performances during test time, while having learned significantly different classification patterns. This phenomenon, which we call prediction discrepancies, is…

Machine Learning · Computer Science 2024-08-01 Xavier Renard , Thibault Laugel , Marcin Detyniecki

With an increasing focus on precision medicine in medical research, numerous studies have been conducted in recent years to clarify the relationship between treatment effects and patient characteristics. The treatment effects for patients…

Methodology · Statistics 2023-09-22 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

Antimicrobial resistance (AMR) poses a mounting global health crisis, requiring rapid and reliable prediction frameworks that capture its complex evolutionary dynamics. Traditional antimicrobial susceptibility testing (AST), while accurate,…

Populations and Evolution · Quantitative Biology 2025-11-18 Anshul Bagaria

Recommender systems are personalized: we expect the results given to a particular user to reflect that user's preferences. Some researchers have studied the notion of calibration, how well recommendations match users' stated preferences,…

Information Retrieval · Computer Science 2019-09-17 Kun Lin , Nasim Sonboli , Bamshad Mobasher , Robin Burke

Machine Learning is proving invaluable across disciplines. However, its success is often limited by the quality and quantity of available data, while its adoption by the level of trust that models afford users. Human vs. machine performance…

When evaluating the efficacy of social programs and medical treatments using randomized experiments, the estimated overall average causal effect alone is often of limited value and the researchers must investigate when the treatments do and…

Applications · Statistics 2013-05-27 Kosuke Imai , Marc Ratkovic

An increasing number of domains are providing us with detailed trace data on human decisions in settings where we can evaluate the quality of these decisions via an algorithm. Motivated by this development, an emerging line of work has…

Artificial Intelligence · Computer Science 2016-06-17 Ashton Anderson , Jon Kleinberg , Sendhil Mullainathan

Machine Learning applications have brought new insights into a secondary analysis of medical data. Machine Learning helps to develop new drugs, define populations susceptible to certain illnesses, identify predictors of many common…

Machine Learning · Computer Science 2020-12-29 YuanZheng Hu , Marina Sokolova

In credence goods markets such as health care or repair services, consumers rely on experts with superior information to adequately diagnose and treat them. Experts, however, are constrained in their diagnostic abilities, which hurts market…

General Economics · Economics 2025-04-28 Alexander Erlei , Lukas Meub

In traditional machine learning techniques, the degree of closeness between true and predicted values generally measures the quality of predictions. However, these learning algorithms do not consider prescription problems where the…

Machine Learning · Computer Science 2021-01-05 Mehmet Kolcu , Alper E. Murat

There is a clear need to involve patients in medical decisions. However, cognitive psychological research has highlighted the cognitive limitations of humans with respect to 1. Probabilistic assessment of the patient state and of potential…

Artificial Intelligence · Computer Science 2021-02-04 Yuval Shahar

High-consequence decision making demands peak performance from individuals in positions of responsibility. Such executive authority bears the obligation to act despite uncertainty, limited resources, time constraints, and accountability…

Computers and Society · Computer Science 2026-04-23 Richard B. Arthur

Restricting randomization in the design of experiments (e.g., using blocking/stratification, pair-wise matching, or rerandomization) can improve the treatment-control balance on important covariates and therefore improve the estimation of…

Econometrics · Economics 2020-11-02 Brian Quistorff , Gentry Johnson

Machine learning models are often trained to predict the outcome resulting from a human decision. For example, if a doctor decides to test a patient for disease, will the patient test positive? A challenge is that historical decision-making…

Machine Learning · Computer Science 2024-04-23 Sidhika Balachandar , Nikhil Garg , Emma Pierson

Data science has the potential to improve business in a variety of verticals. While the lion's share of data science projects uses a predictive approach, to drive improvements these predictions should become decisions. However, such a…

Machine Learning · Computer Science 2022-06-22 Hanan Shteingart , Gerben Oostra , Ohad Levinkron , Naama Parush , Gil Shabat , Daniel Aronovich

Since penicillin was discovered about 90 years ago, we have become used to using drugs to eradicate unwanted pathogenic cells. However, using drugs to kill bacteria, viruses or cancer cells has the serious side effect of selecting for…

Populations and Evolution · Quantitative Biology 2017-08-02 Matti Gralka , Diana Fusco , Stephen Martis , Oskar Hallatschek

Large Language Models (LLMs) are transforming human decision-making by acting as cognitive collaborators. Yet, this promise comes with a paradox: while LLMs can improve accuracy, they may also erode independent reasoning, promote…

Cryptography and Security · Computer Science 2025-09-09 Irdin Pekaric , Philipp Zech , Tom Mattson