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As the amount and complexity of genetic information increases it is necessary that we explore some efficient ways of handling these data. This study takes the "divide and conquer" approach for analyzing high dimensional genomic data. Our…

Applications · Statistics 2013-08-15 Deniz Akdemir

Graph Neural Networks (GNNs) bring the power of deep representation learning to graph and relational data and achieve state-of-the-art performance in many applications. GNNs compute node representations by taking into account the topology…

Machine Learning · Computer Science 2021-09-10 Maria Kalantzi , George Karypis

We propose a novel node embedding of directed graphs to statistical manifolds, which is based on a global minimization of pairwise relative entropy and graph geodesics in a non-linear way. Each node is encoded with a probability density…

Machine Learning · Computer Science 2020-02-07 Thorben Funke , Tian Guo , Alen Lancic , Nino Antulov-Fantulin

Manifold learning flows are a class of generative modelling techniques that assume a low-dimensional manifold description of the data. The embedding of such a manifold into the high-dimensional space of the data is achieved via learnable…

Machine Learning · Statistics 2025-03-07 Kyriakos Flouris , Ender Konukoglu

In recent years, machine learning has been widely adopted to automate the audio mixing process. Automatic mixing systems have been applied to various audio effects such as gain-adjustment, equalization, and reverberation. These systems can…

Sound · Computer Science 2022-09-21 Satvik Venkatesh , David Moffat , Eduardo Reck Miranda

Ontologies contain rich knowledge within domain, which can be divided into two categories, namely extensional knowledge and intensional knowledge. Extensional knowledge provides information about the concrete instances that belong to…

Artificial Intelligence · Computer Science 2026-03-27 Keyu Wang , Guilin Qi , Jiaoyan Chen , Yi Huang , Tianxing Wu

Knowledge Graphs (KG) constitute a flexible representation of complex relationships between entities particularly useful for biomedical data. These KG, however, are very sparse with many missing edges (facts) and the visualisation of the…

Artificial Intelligence · Computer Science 2016-12-08 Armando Vieira

This study explores the use of graph neural networks (GNNs) with hierarchical pooling and multiple convolution layers for cancer classification based on RNA-seq data. We combine gene expression data from The Cancer Genome Atlas (TCGA) with…

Machine Learning · Computer Science 2026-01-13 Thomas Vaitses Fontanari , Mariana Recamonde-Mendoza

Motivation: Modules in gene coexpression networks (GCN) can be regarded as gene groups with individual relationships. No studies have optimized module detection methods to extract diverse gene groups from GCN, especially for data from…

Molecular Networks · Quantitative Biology 2021-12-07 Iori Azuma , Tadahaya Mizuno , Hiroyuki Kusuhara

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Integrative network modeling of data arising from multiple genomic platforms provides insight into the holistic picture of the interactive system, as well as the flow of information across many disease domains including cancer. The basic…

Methodology · Statistics 2020-02-18 Min Jin Ha , Francesco Stingo , Veerabhadran Baladandayuthapani

Graph neural networks (GNNs) are becoming increasingly popular in the medical domain for the tasks of disease classification and outcome prediction. Since patient data is not readily available as a graph, most existing methods either…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Nithya Bhasker , Stefan Leger , Alexander Zwanenburg , Chethan Babu Reddy , Sebastian Bodenstedt , Steffen Löck , Stefanie Speidel

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

We developed OmicsMapNet approach to take advantage of existing deep leaning frameworks to analyze high-dimensional omics data as 2-dimensional images. The omics data of individual samples were first rearranged into 2D images in which…

Machine Learning · Statistics 2019-05-27 Shiyong Ma , Zhen Zhang

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang

The SemanticWeb emerged as an extension to the traditional Web, towards adding meaning to a distributed Web of structured and linked data. At its core, the concept of ontology provides the means to semantically describe and structure…

Artificial Intelligence · Computer Science 2021-05-03 Konstantinos Sikelis , George E Tsekouras , Konstantinos I Kotis

Gene expression programming is an evolutionary optimization algorithm with the potential to generate interpretable and easily implementable equations for regression problems. Despite knowledge gained from previous optimizations being…

Neural and Evolutionary Computing · Computer Science 2025-02-05 Maximilian Reissmann , Yuan Fang , Andrew S. H. Ooi , Richard D. Sandberg

Word embeddings have been shown adept at capturing the semantic and syntactic regularities of the natural language text, as a result of which these representations have found their utility in a wide variety of downstream content analysis…

Computation and Language · Computer Science 2021-03-02 Kishlay Jha

Relational representation learning transforms relational data into continuous and low-dimensional vector representations. However, vector-based representations fall short in capturing crucial properties of relational data that are complex…

Machine Learning · Computer Science 2024-09-25 Bo Xiong

Mapper, a topological algorithm, is frequently used as an exploratory tool to build a graphical representation of data. This representation can help to gain a better understanding of the intrinsic shape of high-dimensional genomic data and…

Genomics · Quantitative Biology 2023-07-19 Erik J. Amézquita , Farzana Nasrin , Kathleen M. Storey , Masato Yoshizawa
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