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Oscillatory activity in auditory cortex is thought to play a central role in auditory and speech processing by synchronizing neural rhythms to external acoustic features of the speech stream. To support this function, cortical oscillators…

Neurons and Cognition · Quantitative Biology 2026-05-11 Yangyang Wang , Benjamin R. Pittman-Polletta

The effects of intrinsic noise on stochastic delay systems is studied within an expansion in the inverse system size. We show that the stochastic nature of the underlying dynamics may induce oscillatory behaviour in parameter ranges where…

Molecular Networks · Quantitative Biology 2015-05-13 Tobias Galla

We introduce a stochastic model describing aggregation of misfolded proteins and degradation by the protein quality control system in a single cell. In analogy with existing literature, aggregates can grow, nucleate and fragment…

Cell Behavior · Quantitative Biology 2012-07-06 Simone Pigolotti , Ludvig Lizana , Daniel Otzen , Kim Sneppen

The inherent instability of oscillatory flows presents a significant challenge in microfluidics, impairing performance in different applications from particle detachemnt to organs-on-a-chip. Trapped air inside a microfluidic system…

Fluid Dynamics · Physics 2025-11-04 Andreu Benavent-Claró

We keep track of the orbital degree of freedom of an exciton polariton condensate, confined in an optical trap, and reveal the stochastic switching of persistent annular polariton currents in the pulse-periodic excitation regime.In an…

Neural synchrony in the brain at rest is usually variable and intermittent, thus intervals of predominantly synchronized activity are interrupted by intervals of desynchronized activity. Prior studies suggested that this temporal structure…

Quantitative Methods · Quantitative Biology 2021-04-26 Joel Zirkle , Leonid L Rubchinsky

We review the mathematical formalism underlying the modelling of stochasticity in biological systems. Beginning with a description of the system in terms of its basic constituents, we derive the mesoscopic equations governing the dynamics…

Populations and Evolution · Quantitative Biology 2012-11-05 Alan J. McKane , Tommaso Biancalani , Tim Rogers

For cellular biochemical reaction systems where the numbers of molecules is small, significant noise is associated with chemical reaction events. This molecular noise can give rise to behavior that is very different from the predictions of…

Molecular Networks · Quantitative Biology 2009-11-13 Matthew Scott , Terence Hwa , Brian Ingalls

We study the effect of external stochastic modulation on a system with O(2) symmetry that exhibits a Hopf or oscillatory instability in the absence of modulation. The study includes a random component in both the control parameter of the…

patt-sol · Physics 2009-10-30 Francois Drolet , Jorge Vinals

The phase-space of a simple synchronization model is thoroughly investigated. The model considers two-mode stochastic oscillators, coupled through a pulse-like interaction controlled by simple optimization rules. A complex phase space is…

Adaptation and Self-Organizing Systems · Physics 2020-12-03 Szabolcs Horvát , Zoltán Néda

Dynamical systems on networks with adaptive couplings appear naturally in real-world systems such as power grid networks, social networks as well as neuronal networks. We investigate a paradigmatic system of adaptively coupled phase…

Adaptation and Self-Organizing Systems · Physics 2019-12-20 Rico Berner , Eckehard Schöll , Serhiy Yanchuk

In neuronal systems, inhibition contributes to stabilizing dynamics and regulating pattern formation. Through developing mean field theories of neuronal models, using complete graph networks, inhibition is commonly viewed as one ``control…

Disordered Systems and Neural Networks · Physics 2024-04-29 Gustavo Menesse , Osame Kinouchi

Phase response curves are important for analysis and modeling of oscillatory dynamics in various applications, particularly in neuroscience. Standard experimental technique for determining them requires isolation of the system and…

Adaptation and Self-Organizing Systems · Physics 2018-09-20 Rok Cestnik , Michael Rosenblum

In neuroscience, synaptic plasticity refers to the set of mechanisms driving the dynamics of neuronal connections, called synapses and represented by a scalar value, the synaptic weight. A Spike-Timing Dependent Plasticity (STDP) rule is a…

Probability · Mathematics 2021-11-17 Philippe Robert , Gaetan Vignoud

We consider a fully-connected network of leaky integrate-and-fire neurons with spike-timing-dependent plasticity. The plasticity is controlled by a parameter representing the expected weight of a synapse between neurons that are firing…

Neurons and Cognition · Quantitative Biology 2011-09-23 Chun-Chung Chen , David Jasnow

Cortical oscillations are thought to be involved in many cognitive functions and processes. Several mechanisms have been proposed to regulate oscillations. One prominent but understudied mechanism is gap-junctional coupling. Gap junctions…

Neurons and Cognition · Quantitative Biology 2018-07-04 Guillaume Pernelle , Wilten Nicola , Claudia Clopath

Understanding the relationship between large-scale structural and functional brain networks remains a crucial issue in modern neuroscience. Recently, there has been growing interest in investigating the role of homeostatic plasticity…

Neurons and Cognition · Quantitative Biology 2018-10-25 Rodrigo P. Rocha , Loren Koçillari , Samir Suweis , Maurizio Corbetta , Amos Maritan

A stochastic model is here introduced to investigate the molecular mechanisms which trigger the perception of pain. The action of analgesic drug compounds is discussed in a dynamical context, where the competition with inactive species is…

Statistical Mechanics · Physics 2009-11-13 Francesca Di Patti , Duccio Fanelli

Biological neural networks are notoriously hard to model due to their stochastic behavior and high dimensionality. We tackle this problem by constructing a dynamical model of both the expectations and covariances of the fractions of active…

Neurons and Cognition · Quantitative Biology 2025-02-25 Vincent Painchaud , Patrick Desrosiers , Nicolas Doyon

We study an excitable active rotator with slowly adapting nonlinear feedback and noise. Depending on the adaptation and the noise level, this system may display noise-induced spiking, noise-perturbed oscillations, or stochastic busting. We…

Adaptation and Self-Organizing Systems · Physics 2020-08-26 Igor Franović , Serhiy Yanchuk , Sebastian Eydam , Iva Bačić , Matthias Wolfrum