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We present the statistical method as a direct extension of the mean first-passage time concept to the analysis of molecular dynamics simulation data of a phase transformation. According to the method, the mean first-passage time…

Soft Condensed Matter · Physics 2015-06-18 Anatolii V. Mokshin , Bulat N. Galimzyanov

We consider a run-and-tumble particle on a half-line with an absorbing target at the origin. The particle has an internal velocity state that switches between two opposite values at Poisson-distributed times. The position of the particle…

Statistical Mechanics · Physics 2025-06-19 Pascal Grange , Linglong Yuan

One-dimensional model of a system where first-order phase transition occurs is examined in the present paper. It is shown that basic properties of the phenomenon, such as a well defined temperature of transition, are caused both by…

Statistical Mechanics · Physics 2009-07-29 Marcin Ostrowski

Interesting theoretical problems of target search or threshold crossing, formally known as {\it first passage}, often arise in both diffusive transport problems as well as problems of chemical reaction kinetics. We study three systems…

Statistical Mechanics · Physics 2025-10-22 Hillol Kumar Barman , Pathik Das , Syed Yunus Ali

We survey recent results on first-passage processes in unbounded cones and their applications to ordering of particles undergoing Brownian motion in one dimension. We first discuss the survival probability S(t) that a diffusing particle, in…

Statistical Mechanics · Physics 2013-06-14 E. Ben-Naim , P. L. Krapivsky

A microcanonical first order transition, connecting a clustered to a homogeneous phase, is studied from both the thermodynamic and dynamical point of view for a N-body Hamiltonian system with infinite-range couplings. In the microcanonical…

Statistical Mechanics · Physics 2007-05-23 Mickael Antoni , Stefano Ruffo , Alessandro Torcini

Projective measurements of a single two-level quantum mechanical system (a qubit) evolving under a time-independent Hamiltonian produce a probability distribution that is periodic in the evolution time. The period of this distribution is an…

Quantum Physics · Physics 2012-06-05 Christopher Ferrie , Christopher E. Granade , D. G. Cory

In this paper we provide an alternative approach to the works of the physicists S. Cocco and R. Monasson about a model of DNA molecules. The aim is to predict the sequence of bases by mechanical stimulations. The model described by the…

Applications · Statistics 2012-02-10 Pierre Andreoletti , Roland Diel

We present a method to investigate the kinetics of protein folding on a long time-scale and the dynamics underlying the formation of secondary and tertiary structures during the entire reaction. The approach is based on the formal analogy…

Biomolecules · Quantitative Biology 2009-11-11 P. Faccioli , M. Sega , F. Pederiva , H. Orland

We investigate the translocation of a single stranded DNA (ssDNA) through a pore, which fluctuates between two conformations, by using coupled master equations (ME). The probability density function (PDF) of the first passage times (FPT) of…

Subcellular Processes · Quantitative Biology 2007-05-23 O. Flomenbom , J. Klafter

The time until the failure of some node of the system or until the end of some stage of the operation of the tribological system is associated with the change in entropy in the system that occurs during this time. Methods of the…

Statistical Mechanics · Physics 2022-08-23 V. V. Ryazanov

Statistical physics models ranging from simple lattice to complex quantum Hamiltonians are one of the mainstays of modern physics, that have allowed both decades of scientific discovery and provided a universal framework to understand a…

Materials Science · Physics 2020-11-30 Sergei V. Kalinin , Mani Valleti , Rama K. Vasudevan , Maxim Ziatdinov

There are problems with defining the thermodynamic limit of systems with long-range interactions; as a result, the thermodynamic behavior of these types of systems is anomalous. In the present work, we review some concepts from both…

Statistical Mechanics · Physics 2009-11-13 L. A. del Pino , P. Troncoso , S. Curilef

Modern biomedicine is challenged to predict the effects of genetic variation. Systematic functional assays of point mutants of proteins have provided valuable empirical information, but vast regions of sequence space remain unexplored.…

Biomolecules · Quantitative Biology 2017-01-18 Thomas A. Hopf , John B. Ingraham , Frank J. Poelwijk , Michael Springer , Chris Sander , Debora S. Marks

Many scientific questions can be framed as asking for a first passage time (FPT), which generically describes the time it takes a random "searcher" to find a "target." The important timescale in a variety of biophysical systems is the time…

Probability · Mathematics 2025-02-18 Hwai-Ray Tung , Sean D Lawley

Non-equilibrium states of a thermodynamic statistical system are investigated using the thermodynamic parameter of the system lifetime, first-passage time, the time before degeneration of the system under influence of fluctuations.…

Statistical Mechanics · Physics 2020-03-19 V. V. Ryazanov

A central goal of protein-folding theory is to predict the stochastic dynamics of transition paths --- the rare trajectories that transit between the folded and unfolded ensembles --- using only thermodynamic information, such as a…

Biomolecules · Quantitative Biology 2018-08-09 William M. Jacobs , Eugene I. Shakhnovich

We propose a scheme for the determination of the coupling parameters in a chain of interacting spins. This requires only time-resolved measurements over a single particle, simple data post-processing and no state initialization or prior…

Quantum Physics · Physics 2009-05-12 C. Di Franco , M. Paternostro , M. S. Kim

Virtually all the emergent properties of a complex system are rooted in the non-homogeneous nature of the behaviours of its elements and of the interactions among them. However, the fact that heterogeneity and correlations can appear…

Physics and Society · Physics 2020-11-13 Aleix Bassolas , Vincenzo Nicosia

Thermal oscillations of base pairs in the Peyrard-Bishop-Holstein model are simulated by stochastic fluctuations of base overlap integrals. Numerical investigation of the model is carried out for a hole transfer in $G_1A_2G_3G_4$ sequence…

Chemical Physics · Physics 2013-03-27 A. S. Shigaev , O. A. Ponomarev , V. D. Lakhno
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