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Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley

Rigorous statistical methods, including parameter estimation with accompanying uncertainties, underpin the validity of scientific discovery, especially in the natural sciences. With increasingly complex data models such as deep learning…

Machine Learning · Computer Science 2026-02-18 Aurora Grefsrud , Nello Blaser , Trygve Buanes

This work presents the concept of kernel mean embedding and kernel probabilistic programming in the context of stochastic systems. We propose formulations to represent, compare, and propagate uncertainties for fairly general stochastic…

Machine Learning · Statistics 2020-05-05 Jia-Jie Zhu , Krikamol Muandet , Moritz Diehl , Bernhard Schölkopf

Exposure characterization in regional risk assessment aims to assign physical properties to the assets of interest so they can be associated with damage and loss functions. While this process has benefited from the growing availability of…

Applications · Statistics 2026-05-12 Chenhao Wu , Henry Burton

Input variables in numerical models are often subject to several levels of uncertainty, usually modeled by probability distributions. In the context of uncertainty quantification applied to these models, studying the robustness of output…

Robustness analysis is an emerging field in the domain of uncertainty quantification. It consists of analysing the response of a computer model with uncertain inputs to the perturbation of one or several of its input distributions. Thus, a…

Statistics Theory · Mathematics 2020-12-16 Clement Gauchy , Jerome Stenger , Roman Sueur , Bertrand Iooss

Two-stage stochastic optimization is a framework for modeling uncertainty, where we have a probability distribution over possible realizations of the data, called scenarios, and decisions are taken in two stages: we make first-stage…

Data Structures and Algorithms · Computer Science 2023-10-25 Andre Linhares , Chaitanya Swamy

We provide methods for in-database support of decision making under uncertainty. Many important decision problems correspond to selecting a package (bag of tuples in a relational database) that jointly satisfy a set of constraints while…

Databases · Computer Science 2021-03-12 Matteo Brucato , Nishant Yadav , Azza Abouzied , Peter J. Haas , Alexandra Meliou

Lyophilization, aka freeze drying, is a process commonly used to increase the stability of various drug products in biotherapeutics manufacturing, e.g., mRNA vaccines, allowing for higher storage temperature. While the current trends in the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-20 Prakitr Srisuma , George Barbastathis , Richard D. Braatz

Uncertainty is a key feature of any machine learning model and is particularly important in neural networks, which tend to be overconfident. This overconfidence is worrying under distribution shifts, where the model performance silently…

Machine Learning · Computer Science 2024-03-18 Arthur Thuy , Dries F. Benoit

Unlike classification, whose goal is to estimate the class of each data point in a dataset, prevalence estimation or quantification is a task that aims to estimate the distribution of classes in a dataset. The two main tasks in prevalence…

Machine Learning · Statistics 2025-07-09 Aime Bienfait Igiraneza , Christophe Fraser , Robert Hinch

We study the robustness of system estimation to parametric perturbations in system dynamics and initial conditions. We define the problem of sensitivity-based parametric uncertainty quantification in dynamical system estimation. The main…

Systems and Control · Electrical Eng. & Systems 2025-09-09 Ayush Pandey

Statistical model checking estimates probabilities and expectations of interest in probabilistic system models by using random simulations. Its results come with statistical guarantees. However, many tools use unsound statistical methods…

Logic in Computer Science · Computer Science 2025-09-15 Carlos E. Budde , Arnd Hartmanns , Tobias Meggendorfer , Maximilian Weininger , Patrick Wienhöft

Safe control of constrained linear systems under both epistemic and aleatory uncertainties is considered. The aleatory uncertainty characterizes random noises and is modeled by a probability distribution function (PDF) and the epistemic…

Systems and Control · Electrical Eng. & Systems 2022-10-28 Hamidreza Modares

Many trials are designed to collect outcomes at or around pre-specified times after randomization. If there is variability in the times when participants are actually assessed, this can pose a challenge to learning the effect of treatment,…

Statistical models typically capture uncertainties in our knowledge of the corresponding real-world processes, however, it is less common for this uncertainty specification to capture uncertainty surrounding the values of the inputs to the…

Methodology · Statistics 2023-05-10 Samuel E. Jackson , David C. Woods

Uncertainty quantification has been a core of the statistical machine learning, but its computational bottleneck has been a serious challenge for both Bayesians and frequentists. We propose a model-based framework in quantifying…

Machine Learning · Computer Science 2019-06-04 Minsuk Shin , Young Lee , Jun S. Liu

The uncertainty quantifications of theoretical results are of great importance to make meaningful comparisons of those results with experimental data and to make predictions in experimentally unknown regions. By quantifying uncertainties,…

Nuclear Theory · Physics 2018-12-10 Sota Yoshida , Noritaka Shimizu , Tomoaki Togashi , Takaharu Otsuka

The application of machine learning (ML) techniques in wireless communication domain has seen a tremendous growth over the years especially in the wireless sensing domain. However, the questions surrounding the ML model's inference…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Amit Kachroo , Sai Prashanth Chinnapalli

Common statistical measures of uncertainty such as $p$-values and confidence intervals quantify the uncertainty due to sampling, that is, the uncertainty due to not observing the full population. However, sampling is not the only source of…

Methodology · Statistics 2024-07-08 Suyash Gupta , Dominik Rothenhäusler