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Phase-contrast microscopy converts the optical phase introduced by transparent, unlabeled specimens into modulation in the intensity image. Modern phase imaging techniques are capable of quantifying phase shift at each point in the field of…

In-situ measurements of space plasma throughout the solar system require high time resolution to understand the plasma's kinetic fine structure and evolution. In this context, research~is conducted to design instruments with the capability…

Instrumentation and Detectors · Physics 2020-12-01 Benjamin Criton , Georgios Nicolaou , Daniel Verscharen

We present MBIS (Multivariate Bayesian Image Segmentation tool), a clustering tool based on the mixture of multivariate normal distributions model. MBIS supports multi-channel bias field correction based on a B-spline model. A second…

Computer Vision and Pattern Recognition · Computer Science 2015-11-19 Oscar Esteban , Gert Wollny , Subrahmanyam Gorthi , Maria-J. Ledesma-Carbayo , Jean-Philippe Thiran , Andres Santos , Meritxell Bach-Cuadra

Tissue biopsy is the gold standard for diagnosing many diseases, involving the extraction of diseased tissue for histopathology analysis by expert pathologists. However, this procedure has two main limitations: 1) Manual sampling through…

Robotics · Computer Science 2025-09-03 Fanxin Wang , Yikun Cheng , Chuyuan Tao , Rohit Bhargava , Thenkurussi Kesavadas

Perinatal stroke (PS) is a serious condition that, if undetected and thus untreated, often leads to life-long disability, in particular Cerebral Palsy (CP). In clinical settings, Prechtl's General Movement Assessment (GMA) can be used to…

Human-Computer Interaction · Computer Science 2019-02-22 Yan Gao , Yang Long , Yu Guan , Anna Basu , Jessica Baggaley , Thomas Ploetz

Continuous ambulatory monitoring of peripheral vascular perfusion could enable earlier detection of vascular dysfunction in individuals with diabetes mellitus and more timely management of cardiovascular disease. Clinical imaging modalities…

Optical microscopy has long been the standard method for diagnosis in cytopathology. Whole slide scanners can image and digitize large sample areas automatically, but are slow, expensive and therefore not widely available. Clinical…

Magnetic particle imaging (MPI) is a tracer-based medical imaging modality that enables quantification and spatial mapping of magnetic nanoparticle (MNP) distribution. The magnetization response of MNPs depends on experimental conditions…

Signal Processing · Electrical Eng. & Systems 2025-09-03 Asli Alpman , Mustafa Utkur , Emine Ulku Saritas

Magnetic Particle Imaging (MPI) has been shown to provide remarkable contrast for imaging applications such as angiography, stem cell tracking, and cancer imaging. Recently, there is growing interest in the functional imaging capabilities…

Medical Physics · Physics 2017-04-26 Mustafa Utkur , Yavuz Muslu , Emine Ulku Saritas

Confocal microscopy is the cornerstone of cellular biology and biomedical research due to its non-destructive imaging, compatibility with live cells, sensitivity, optical sectioning, and subcellular resolution. To meet the demand for rapid…

In the 21st century, biosensors have gathered much wider attention than ever before, irrespective of the technology that promises to bring them forward. With the recent COVID-19 outbreak, the concern and efforts to restore global health and…

Medical Physics · Physics 2023-02-14 Vinayak Pachkawade

Recent advances in medical diagnostics have highlighted the importance of wearable technologies for continuous and real-time physiological monitoring. In this study, we introduce a flexible, self-powered triboelectric nanogenerator…

Medical Physics · Physics 2025-08-19 Cai Lin , Yunyi Ding , Kai Lin , Ru Wang , Yichen Luo , Xiaofen Wu

Increasing sensitivity and signal to noise ratios of conventional wave sensors is an interesting topic in structural health monitoring, medical imaging, aerospace and nuclear instrumentation. Here, we report the concept of a gradient…

Materials Science · Physics 2016-05-27 Y. Y. Chen , R. Zhu , M. V. Barnhart , G. L. Huang

Organic molecules with nonlinear optical behavior have advanced a wide range of fields spanning from integrated photonics to biological imaging. With advances in microscopy, an emerging application is multifunctional nonlinear organic…

Mycoplasma pneumoniae pneumonia (MPP) poses significant diagnostic challenges in pediatric healthcare, especially in regions like China where it's prevalent. We introduce PneumoniaAPP, a mobile application leveraging deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Jiaming Deng , Zhenglin Chen , Minjiang Chen , Lulu Xu , Jiaqi Yang , Zhendong Luo , Peiwu Qin

A custom-developed magneto-mechanical resonator (MMR) for wireless pressure measurement is investigated for potential applications in process engineering. The MMR sensor utilises changes in the resonance frequency caused by pressure on a…

We propose a multi-dimensional persistent sheaf Laplacian (MPSL) framework on simplicial complexes for image analysis. The proposed method is motivated by the strong sensitivity of commonly used dimensionality reduction techniques, such as…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Xiang Xiang Wang , Guo-Wei Wei

The growing demand for continuous physiological monitoring and human-machine interaction in real-world settings calls for wearable platforms that are flexible, low-power, and capable of on-device intelligence. This work presents…

Systems and Control · Electrical Eng. & Systems 2025-12-16 Sebastian Frey , Giusy Spacone , Andrea Cossettini , Marco Guermandi , Philipp Schilk , Luca Benini , Victor Kartsch

Accurate assessment of burn severity at injury onset remains a major clinical challenge due to the lack of objective methods for detecting subsurface tissue damage. This limitation is critical in battlefield and mass-casualty settings,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Nathaniel Hanson , Mateusz Wolak , Jonathan Richardson , Patrick Walker , David M. Burmeister , Chakameh Jafari

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M…

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