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Objective. The COVID-19 pandemic has threatened to collapse hospital and ICU services, and it has affected the care programs for non-COVID patients. The objective was to develop a mathematical model designed to optimize predictions related…

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing…

The current COVID-19 pandemic poses numerous challenges for ongoing clinical trials and provides a stress-testing environment for the existing principles and practice of estimands in clinical trials. The pandemic may increase the rate of…

Methodology · Statistics 2023-02-02 Yongming Qu , Ilya Lipkovich

Standard epidemiological models for COVID-19 employ variants of compartment (SIR) models at local scales, implicitly assuming spatially uniform local mixing. Here, we examine the effect of employing more geographically detailed diffusion…

We sample aggravated cases following age-structured probabilities from confirmed cases and use ICU occupation data to find a subnotification factor. A logistic fit is then employed to project the progression of the COVID-19 epidemic with…

Physics and Society · Physics 2024-02-14 Rodrigo Veiga , Rodrigo Murta , Renato Vicente

Epidemics are a serious public health threat, and the resources for mitigating their effects are typically limited. Decision-makers face challenges in forecasting the supply and demand for these resources as prior information about the…

As the COVID-19 outbreak evolves, accurate forecasting continues to play an extremely important role in informing policy decisions. In this paper, we present our continuous curation of a large data repository containing COVID-19 information…

More than ever COVID-19 is putting pressure on health systems all around the world, especially in Brazil. In this study we propose an analytical approach based on statistics and machine learning that uses lab exam data coming from patients…

Machine Learning · Computer Science 2020-11-09 Vitor Bezzan , Cleber D. Rocco

The U.S. Covid-19 data exhibit a high-frequency oscillation along a low-frequency wave for outbreaks. There is no model to account for it. A modified SIR model is proposed to explain this spiking phenomenon. It is also used to best-fit the…

Populations and Evolution · Quantitative Biology 2023-11-21 Bo Deng

Estimating the lengths-of-stay (LoS) of hospitalised COVID-19 patients is key for predicting the hospital beds' demand and planning mitigation strategies, as overwhelming the healthcare systems has critical consequences for disease…

Methodology · Statistics 2024-01-30 Ana López-Cheda , M. Amalia Jácome , Ricardo Cao , Pablo M. De Salazar

Early diagnosis of disease can lead to improved health outcomes, including higher survival rates and lower treatment costs. With the massive amount of information available in electronic health records (EHRs), there is great potential to…

Machine Learning · Computer Science 2022-08-02 Asem Alaa , Erik Mayer , Mauricio Barahona

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

Accurate models of patient survival probabilities provide important information to clinicians prescribing care for life-threatening and terminal ailments. A recently developed class of models - known as individual survival distributions…

Machine Learning · Computer Science 2019-06-27 Samuel Sokota , Ryan D'Orazio , Khurram Javed , Humza Haider , Russell Greiner

Using the classical Susceptible-Infected-Recovered epidemiological model, an analytical formula is derived for the number of beds occupied by Covid-19 patients. The analytical curve is fitted to data in Belgium, France, New York City and…

Populations and Evolution · Quantitative Biology 2021-02-22 Gregory Kozyreff

Throughout the coronavirus disease 2019 (COVID-19) pandemic, decision makers have relied on forecasting models to determine and implement non-pharmaceutical interventions (NPI). In building the forecasting models, continuously updated…

The fast transmission rate of COVID-19 worldwide has made this virus the most important challenge of year 2020. Many mitigation policies have been imposed by the governments at different regional levels (country, state, county, and city) to…

Applications · Statistics 2022-05-04 Yue Bai , Abolfazl Safikhani , George Michailidis

The COVID-19 pandemic has significantly impacted the tourism and hospitality sector. Public policies such as travel restrictions and stay-at-home orders had significantly affected tourist activities and service businesses' operations and…

Machine Learning · Computer Science 2022-03-10 Ashkan Farhangi , Arthur Huang , Zhishan Guo

Susceptible-Invective-Recovered (SIR) mathematical models are in high demand due to the COVID-19 pandemic. They are used in their standard formulation, or through the many variants, trying to fit and hopefully predict the number of new…

Populations and Evolution · Quantitative Biology 2020-05-19 Ben-Hur Francisco Cardoso , Sebastián Gonçalves

We present a resource-planning tool for hospitals under special consideration of the COVID-19 pandemic, called babsim.hospital. It provides many advantages for crisis teams, e.g., comparison with their own local planning, simulation of…

Applications · Statistics 2020-12-15 Thomas Bartz-Beielstein , Frederik Rehbach , Olaf Mersmann , Eva Bartz

In this paper, we propose a new real-time differential virus transmission model, which can give more accurate and robust short-term predictions of COVID-19 transmitted infectious disease with benefits of near-term trend projection.…

Populations and Evolution · Quantitative Biology 2020-05-05 Sheldon X. D. Tan , Liang Chen