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Histological classification of colorectal polyps plays a critical role in both screening for colorectal cancer and care of affected patients. An accurate and automated algorithm for the classification of colorectal polyps on digitized…

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Colorectal cancer (CRC) remains one of the leading causes of cancer-related morbidity and mortality worldwide, with gastrointestinal (GI) polyps serving as critical precursors according to the World Health Organization (WHO). Early and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Akwasi Asare , Thanh-Huy Nguyen , Ulas Bagci

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

Quantitative Methods · Quantitative Biology 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

Deep learning assisted digital pathology has the potential to impact clinical practice in significant ways. In recent studies, deep neural network (DNN) enabled analysis outperforms human pathologists. Increasing sizes and complexity of the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Haowen Zhou , Steven , Lin , Mark Watson , Cory T. Bernadt , Oumeng Zhang , Ramaswamy Govindan , Richard J. Cote , Changhuei Yang

Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted…

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately…

Machine Learning · Computer Science 2021-11-08 Xingyu Li , Jitendra Jonnagaddala , Shuhua Yang , Hong Zhang , Xu Steven Xu

Diabetic retinopathy (DR) screening is instrumental in preventing blindness, but faces a scaling challenge as the number of diabetic patients rises. Risk stratification for the development of DR may help optimize screening intervals to…

Lung squamous cell carcinoma (LSCC) has a high recurrence and metastasis rate. Factors influencing recurrence and metastasis are currently unknown and there are no distinct histopathological or morphological features indicating the risks of…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Weicheng Zhu , Carlos Fernandez-Granda , Narges Razavian

Time-to-event prediction, e.g. cancer survival analysis or hospital length of stay, is a highly prominent machine learning task in medical and healthcare applications. However, only a few interpretable machine learning methods comply with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Hubert Baniecki , Bartlomiej Sobieski , Patryk Szatkowski , Przemyslaw Bombinski , Przemyslaw Biecek

Past few years have witnessed the prevalence of deep learning in many application scenarios, among which is medical image processing. Diagnosis and treatment of brain tumors requires an accurate and reliable segmentation of brain tumors as…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Feifan Wang , Runzhou Jiang , Liqin Zheng , Chun Meng , Bharat Biswal

Colorectal cancer (CRC) remains a significant cause of cancer-related mortality, despite the widespread implementation of prophylactic initiatives aimed at detecting and removing precancerous polyps. Although screening effectively reduces…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Ahmed Rahu , Brian Shula , Brandon Combs , Aqsa Sultana , Surendra P. Singh , Vijayan K. Asari , Derrick Forchetti

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Krithik Ramesh , Ritvik Koneru

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

Estimating over-amplification of human epidermal growth factor receptor 2 (HER2) on invasive breast cancer (BC) is regarded as a significant predictive and prognostic marker. We propose a novel deep reinforcement learning (DRL) based model…

Computer Vision and Pattern Recognition · Computer Science 2019-03-27 Talha Qaiser , Nasir M. Rajpoot

Background and Objective: Colorectal cancer is a high mortality cancer. Clinical data analysis plays a crucial role in predicting the survival of colorectal cancer patients, enabling clinicians to make informed treatment decisions. However,…

Machine Learning · Computer Science 2023-09-06 Sadegh Soleimani , Mahsa Bahrami , Mansour Vali

Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathological features, overlooking other important CRC risk factors.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Shuai Jiang , Christina Robinson , Joseph Anderson , William Hisey , Lynn Butterly , Arief Suriawinata , Saeed Hassanpour

Traditional image-based survival prediction models rely on discriminative patch labeling which make those methods not scalable to extend to large datasets. Recent studies have shown Multiple Instance Learning (MIL) framework is useful for…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Jiawen Yao , Xinliang Zhu , Jitendra Jonnagaddala , Nicholas Hawkins , Junzhou Huang