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Model-based approaches for image reconstruction, analysis and interpretation have made significant progress over the last decades. Many of these approaches are based on either mathematical, physical or biological models. A challenge for…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Daniel Rueckert , Julia A. Schnabel

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Classification of HEp-2 cell patterns plays a significant role in the indirect immunofluorescence test for identifying autoimmune diseases in the human body. Many automatic HEp-2 cell classification methods have been proposed in recent…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Saimunur Rahman , Lei Wang , Changming Sun , Luping Zhou

Histopathology, the microscopic study of diseased tissue, is increasingly digitized, enabling improved visualization and streamlined workflows. An important task in histopathology is the segmentation of cells and glands, essential for…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Philipp Endres , Valentin Koch , Julia A. Schnabel , Carsten Marr

The aim of this study is to propose an alternative and hybrid solution method for diagnosing the disease from histopathology images taken from animals with paratuberculosis and intact intestine. In detail, the hybrid method is based on…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Nilgun Sengoz , Tuncay Yigit , Ozlem Ozmen , Ali Hakan Isik

Recent advances in types and extent of medical imaging technologies has led to proliferation of multimodal quantitative imaging data in cancer. Quantitative medical imaging data refer to numerical representations derived from medical…

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

It is imperative that breast cancer is detected precisely and timely to improve patient outcomes. Diagnostic methodologies have traditionally relied on unimodal approaches; however, medical data analytics is integrating diverse data sources…

Machine Learning · Computer Science 2024-06-21 Faseela Abdullakutty , Younes Akbari , Somaya Al-Maadeed , Ahmed Bouridane , Rifat Hamoudi

Histopathology plays a central role in diagnosis of many diseases including solid cancers. Efforts are underway to transform this subjective art form to an objective and quantitative science. Coherent Raman imaging (CRI), a label-free…

Medical Physics · Physics 2018-02-07 Marcus T Cicerone , Charles H. Camp

Microscopy image enhancement plays a pivotal role in understanding the details of biological cells and materials at microscopic scales. In recent years, there has been a significant rise in the advancement of microscopy image enhancement,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-29 Debasish Dutta , Neeharika Sonowal , Risheraj Barauh , Deepjyoti Chetia , Sanjib Kr Kalita

Morphological profiling is a valuable tool in phenotypic drug discovery. The advent of high-throughput automated imaging has enabled the capturing of a wide range of morphological features of cells or organisms in response to perturbations…

One issue with computer based histopathology image analysis is that the size of the raw image is usually very large. Taking the raw image as input to the deep learning model would be computationally expensive while resizing the raw image to…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Bolei Xu , Jingxin Liu , Xianxu Hou , Bozhi Liu , Jon Garibaldi , Ian O. Ellis , Andy Green , Linlin Shen , Guoping Qiu

Automation in medical imaging is quite challenging due to the unavailability of annotated datasets and the scarcity of domain experts. In recent years, deep learning techniques have solved some complex medical imaging tasks like disease…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Soumyajyoti Dey , Sukanta Chakraborty , Utso Guha Roy , Nibaran Das

Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

The field of medical imaging is an essential aspect of the medical sciences, involving various forms of radiation to capture images of the internal tissues and organs of the body. These images provide vital information for clinical…

Artificial Intelligence · Computer Science 2023-06-21 Shuvra Sarker , Angona Biswas , MD Abdullah Al Nasim , Md Shahin Ali , Sai Puppala , Sajedul Talukder

The field of computational pathology presents many challenges for computer vision algorithms due to the sheer size of pathology images. Histopathology images are large and need to be split up into image tiles or patches so modern…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Rob Jewsbury , Abhir Bhalerao , Nasir Rajpoot

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

Recent advances in digital imaging has transformed computer vision and machine learning to new tools for analyzing pathology images. This trend could automate some of the tasks in the diagnostic pathology and elevate the pathologist…

Computer Vision and Pattern Recognition · Computer Science 2020-05-11 Manit Zaveri , Shivam Kalra , Morteza Babaie , Sultaan Shah , Savvas Damskinos , Hany Kashani , H. R. Tizhoosh

Computational pathology is part of precision oncology medicine. The integration of high-throughput data including genomics, transcriptomics, proteomics, metabolomics, pathomics, and radiomics into clinical practice improves cancer treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-07 Liangrui Pan , Zhichao Feng , Shaoliang Peng