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Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

Machine Learning · Computer Science 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

This paper is concerned with a family of Reaction-Diffusion systems that we introduced in [15], and that generalizes the SIR type models from epidemiology. Such systems are now also used to describe collective behaviors.In this paper, we…

Analysis of PDEs · Mathematics 2021-02-16 Henri Berestycki , Samuel Nordmann , Luca Rossi

Forecasts of the trajectory of an infectious agent can help guide public health decision making. A traditional approach to forecasting fits a computational model to structured data and generates a predictive distribution. However, human…

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris

Tuberculosis (TB) remains a formidable global health challenge, driven by complex spatiotemporal transmission dynamics and influenced by factors such as population mobility and behavioral changes. We propose an Epidemic-Guided Deep Learning…

Machine Learning · Computer Science 2025-10-29 Madhab Barman , Madhurima Panja , Nachiketa Mishra , Tanujit Chakraborty

Experiments on online marketplaces and social networks suffer from interference, where the outcome of a unit is impacted by the treatment status of other units. We propose a framework for modeling interference using a ubiquitous deployment…

Methodology · Statistics 2023-08-21 Ariel Boyarsky , Hongseok Namkoong , Jean Pouget-Abadie

We compare two multi-state modelling frameworks that can be used to represent dates of events following hospital admission for people infected during an epidemic. The methods are applied to data from people admitted to hospital with…

We propose a new nonparametric modeling framework for causal inference when outcomes depend on how agents are linked in a social or economic network. Such network interference describes a large literature on treatment spillovers, social…

Econometrics · Economics 2025-03-25 Eric Auerbach , Hongchang Guo , Max Tabord-Meehan

Understanding the spread of COVID-19 has been the subject of numerous studies, highlighting the significance of reliable epidemic models. Here, we introduce a novel epidemic model using a latent Hawkes process with temporal covariates for…

Methodology · Statistics 2022-08-16 Stamatina Lamprinakou , Axel Gandy , Emma McCoy

Recent advancements in Large Language Models offer promising capabilities to simulate complex human social interactions. We investigate whether LLM-based multi-agent simulations can reproduce core human social dynamics observed in online…

Multiagent Systems · Computer Science 2025-07-31 Hsien-Tsung Lin , Pei-Cing Huang , Chan-Tung Ku , Chan Hsu , Pei-Xuan Shieh , Yihuang Kang

The outbreak of the coronavirus disease 2019 (COVID-19) has now spread throughout the globe infecting over 150 million people and causing the death of over 3.2 million people. Thus, there is an urgent need to study the dynamics of…

Agent-based models capture heterogeneity among individuals in a population and are widely used in studies of multi-cellular systems, disease, epidemics and demography to name a few. However, existing frameworks consider discrete time-step…

Populations and Evolution · Quantitative Biology 2024-10-03 Paul Piho , Philipp Thomas

In recent advancements in Multi-agent Reinforcement Learning (MARL), its application has extended to various safety-critical scenarios. However, most methods focus on online learning, which presents substantial risks when deployed in…

Artificial Intelligence · Computer Science 2024-10-01 Jianuo Huang

The onset of the COVID-19 pandemic drove a widespread, often uncoordinated effort by research groups to develop mathematical models of SARS-CoV-2 to study its spread and inform control efforts. The urgent demand for insight at the outset of…

Populations and Evolution · Quantitative Biology 2023-06-21 Alexander N. Pillai , Kok Ben Toh , Dianela Perdomo , Sanjana Bhargava , Arlin Stoltzfus , Ira M. Longini , Carl A. B. Pearson , Thomas J. Hladish

We introduce the concept of epidemic-fitted wavelets which comprise, in particular, as special cases the number $I(t)$ of infectious individuals at time $t$ in classical SIR models and their derivatives. We present a novel method for…

Deep research tools are among the most impactful and most commonly encountered agentic systems today. We observe, however, that each deep research agent introduced so far is hard-coded to carry out a particular research strategy using a…

Artificial Intelligence · Computer Science 2025-09-03 Peter Belcak , Pavlo Molchanov

Agent-based simulation provides a powerful tool for in silico system modeling. However, these simulations do not provide built-in methods for uncertainty quantification (UQ). Within these types of models a typical approach to UQ is to run…

Applications · Statistics 2025-04-17 Adam Spannaus , Sifat Afroj Moon , John Gounley , Heidi A. Hanson

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments. Agent-based models (ABMs) are an increasingly popular…

The coronavirus disease (COVID-19) pandemic has changed our lives and still poses a challenge to science. Numerous studies have contributed to a better understanding of the pandemic. In particular, inhalation of aerosolised pathogens has…

Populations and Evolution · Quantitative Biology 2022-09-02 Simon Rahn , Marion Gödel , Gerta Köster , Gesine Hofinger

Effective decision-making in complex systems requires synthesizing diverse perspectives to address multifaceted challenges under uncertainty. This study introduces an agentic Large Language Models (LLMs) framework for simulating decision…

Artificial Intelligence · Computer Science 2026-03-20 Antoine Dolant , Praveen Kumar