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Clinical trials are essential for drug development but often suffer from expensive, inaccurate and insufficient patient recruitment. The core problem of patient-trial matching is to find qualified patients for a trial, where patient…

Artificial Intelligence · Computer Science 2021-04-13 Xingyao Zhang , Cao Xiao , Lucas M. Glass , Jimeng Sun

Despite the major advances taken in causal modeling, causality is still an unfamiliar topic for many statisticians. In this paper, it is demonstrated from the beginning to the end how causal effects can be estimated from observational data…

Methodology · Statistics 2014-07-03 Juha Karvanen

Causal representation learning seeks to uncover causal relationships among high-level latent variables from low-level, entangled, and noisy observations. Existing approaches often either rely on deep neural networks, which lack…

Methodology · Statistics 2026-03-27 Wenjin Zhang , Yixin Wang , Yuqi Gu

ML is playing an increasingly crucial role in estimating causal effects of treatments on outcomes from observational data. Many ML methods (`causal estimators') have been proposed for this task. All of these methods, as with any ML…

Machine Learning · Computer Science 2025-10-06 Damian Machlanski , Spyridon Samothrakis , Paul Clarke

Predicting diagnoses from Electronic Health Records (EHRs) is an important medical application of multi-label learning. We propose a convolutional residual model for multi-label classification from doctor notes in EHR data. A given patient…

Machine Learning · Statistics 2018-08-10 Xinyuan Zhang , Ricardo Henao , Zhe Gan , Yitong Li , Lawrence Carin

Deep learning vulnerability detection has shown promising results in recent years. However, an important challenge that still blocks it from being very useful in practice is that the model is not robust under perturbation and it cannot…

Software Engineering · Computer Science 2024-01-17 Md Mahbubur Rahman , Ira Ceka , Chengzhi Mao , Saikat Chakraborty , Baishakhi Ray , Wei Le

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

Artificial Intelligence · Computer Science 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

The estimation of causal effects with observational data continues to be a very active research area. In recent years, researchers have developed new frameworks which use machine learning to relax classical assumptions necessary for the…

Machine Learning · Statistics 2024-05-01 Jonathan Fuhr , Philipp Berens , Dominik Papies

Healthcare continues to grapple with the persistent issue of treatment disparities, sparking concerns regarding the equitable allocation of treatments in clinical practice. While various fairness metrics have emerged to assess fairness in…

Machine Learning · Computer Science 2024-01-09 Linying Zhang , Lauren R. Richter , Yixin Wang , Anna Ostropolets , Noemie Elhadad , David M. Blei , George Hripcsak

Large-scale pretraining has transformed modeling of language and other data types, but its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present a novel generative pretraining strategy…

Electroencephalography (EEG) is a complex signal and can require several years of training to be correctly interpreted. Recently, deep learning (DL) has shown great promise in helping make sense of EEG signals due to its capacity to learn…

Machine Learning · Computer Science 2019-01-23 Yannick Roy , Hubert Banville , Isabela Albuquerque , Alexandre Gramfort , Tiago H. Falk , Jocelyn Faubert

Causal inference is a critical task across fields such as healthcare, economics, and the social sciences. While recent advances in machine learning, especially those based on the deep-learning architectures, have shown potential in…

Machine Learning · Statistics 2024-12-30 Manqing Liu , David R. Bellamy , Andrew L. Beam

The convenient access to copious multi-faceted data has encouraged machine learning researchers to reconsider correlation-based learning and embrace the opportunity of causality-based learning, i.e., causal machine learning (causal…

Machine Learning · Computer Science 2022-02-08 Lu Cheng , Ruocheng Guo , Raha Moraffah , Paras Sheth , K. Selcuk Candan , Huan Liu

Recent years, the database committee has attempted to develop automatic database management systems. Although some researches show that the applying AI to data management is a significant and promising direction, there still exists many…

Databases · Computer Science 2021-11-23 Yu Yan , Hongzhi Wang , Jian Ma , Jian Geng , Yuzhuo Wang

Causal modeling provides us with powerful counterfactual reasoning and interventional mechanism to generate predictions and reason under various what-if scenarios. However, causal discovery using observation data remains a nontrivial task…

Machine Learning · Computer Science 2023-01-06 Jawad Chowdhury , Rezaur Rashid , Gabriel Terejanu

Causal discovery from time series data encompasses many existing solutions, including those based on deep learning techniques. However, these methods typically do not endorse one of the most prevalent paradigms in deep learning: End-to-end…

Machine Learning · Computer Science 2024-02-15 Gideon Stein , Maha Shadaydeh , Joachim Denzler

Electronic health records (EHR) data provide a cost and time-effective opportunity to conduct cohort studies of the effects of multiple time-point interventions in the diverse patient population found in real-world clinical settings.…

Electronic Health Records (EHRs) provide a wealth of information for machine learning algorithms to predict the patient outcome from the data including diagnostic information, vital signals, lab tests, drug administration, and demographic…

Machine Learning · Computer Science 2021-06-16 Byunggill Joe , Akshay Mehra , Insik Shin , Jihun Hamm

Although increasingly used as a data resource for assembling cohorts, electronic health records (EHRs) pose many analytic challenges. In particular, a patient's health status influences when and what data are recorded, generating sampling…

Methodology · Statistics 2020-04-28 Yifei Sun , Charles E. McCulloch , Kieren A. Marr , Chiung-Yu Huang

Causal representation learning (CRL) models aim to transform high-dimensional data into a latent space, enabling interventions to generate counterfactual samples or modify existing data based on the causal relationships among latent…

Machine Learning · Computer Science 2026-03-19 Alireza Sadeghi , Wael AbdAlmageed
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