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The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) has posed a serious threat to global health. As no specific therapeutics are yet available to control disease evolution, more in-depth…

Viral transmission pathways have profound implications for public safety; it is thus imperative to establish a complete understanding of viable infectious avenues. Mounting evidence suggests SARS-CoV-2 can be transmitted via the air;…

Populations and Evolution · Quantitative Biology 2021-03-31 John M. Kolinski , Tobias M. Schneider

Airborne respiratory diseases such as SARS-CoV-2 (COVID-19) pose significant challenges for public transportation. Several recent outbreaks of SARS-CoV-2 indicate the high risk of transmission among passengers on public buses if special…

Fluid Dynamics · Physics 2021-02-03 Zhihang Zhang , Taehoon Han , Kwang Hee Yoo , Jesse Capecelatro , Andre Boehman , Kevin Maki

In this work we propose the design principles of a stochastic graph-based model for the simulation of SARS-CoV-2 transmission. The proposed approach incorporates three sub-models, namely, the spatial model, the mobility model, and the…

Physics and Society · Physics 2021-11-11 Christos Chondros , Stavros D. Nikolopoulos , Iosif Polenakis

Airborne transmission has been recognized as an important route of transmission for SARS-CoV-2, the virus responsible for the COVID-19 pandemic. While coughing and sneezing are spectacular sources of production of infected aerosols with…

Fluid Dynamics · Physics 2024-05-09 Oğuzhan Kaplan , Manouk Abkarian , Simon Mendez

The present work shows that it is possible to analytically solve a general model to explain the transmission dynamics of SARS-CoV-2. First, the within-host model is described, and later a between-host model, where the coupling between them…

Populations and Evolution · Quantitative Biology 2023-08-07 Raul Isea

The devastating impact of the COVID-19 pandemic caused by SARS coronavirus 2 (SARS CoV 2) has raised important questions about viral origin, mechanisms of zoonotic transfer to humans, whether companion or commercial animals can act as…

Biomolecules · Quantitative Biology 2021-07-12 Sakshi Piplani , Puneet Kumar Singh , David A. Winkler , Nikolai Petrovsky

The current SARS-CoV-2 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers. In this snapshot, our aim is to provide a…

Other Quantitative Biology · Quantitative Biology 2020-04-01 Yinon M. Bar-On , Avi I. Flamholz , Rob Phillips , Ron Milo

SARS-CoV-2 is an upper respiratory system RNA virus that has caused over 3 million deaths and infecting over 150 million worldwide as of May 2021. With thousands of strains sequenced to date, SARS-CoV-2 mutations pose significant challenges…

Quantitative Methods · Quantitative Biology 2021-11-15 Yanyi Ding , Zhiyi Kuang , Yuxin Pei , Jeff Tan , Ziyu Zhang , Joseph Konan

Interactions between SARS-CoV-2 and human proteins (SARS-CoV-2 PPIs) cause information transfer through biochemical pathways that contribute to the immunopathology of COVID-19. Here, we present a communication network model of the immune…

Molecular Networks · Quantitative Biology 2022-08-15 Swarnavo Sarkar

Network scientists have proposed that infectious diseases involving person-to-person transmission may be effectively halted by targeting interventions at a minority of highly connected individuals. Can this strategy be effective in…

Social and Information Networks · Computer Science 2020-11-16 Gianluca Manzo , Arnout van de Rijt

The new coronavirus (2019-nCoV or SARS-CoV2), inducing the current pandemic disease (COVID-19) and causing pneumoniae in humans, is dramatically increasing in epidemic scale since its first appearance in Wuhan, China, in December 2019. The…

Molecular Networks · Quantitative Biology 2020-03-28 Maria Luisa Chiusano

The COVID-19 pandemic is spreading rapidly around the world, causing countries to impose lockdowns and efforts to develop vaccines on a global scale. However, human-to-animal and animal-to-human transmission cannot be ignored, as severe…

Populations and Evolution · Quantitative Biology 2024-08-20 Zi Hian Tan , Kian Yan Yong , Jian-Jun Shu

In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and propagated worldwide as a pandemic. In the absence of preventive medicine or a ready to use vaccine, mathematical models can provide useful scientific insights…

Populations and Evolution · Quantitative Biology 2020-06-30 Indrajit Ghosh

Facing a global challenge with over 6.9 million fatalities, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoViD-19, demands novel and comprehensive approaches to understand its complex dynamics. This…

Dynamical Systems · Mathematics 2023-06-05 João Paulo Simões Maurício de Carvalho

COVID-19 is a devastating respiratory and inflammatory illness caused by a new coronavirus that is rapidly spreading throughout the human population. Over the past 6 months, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the…

The SARS-CoV-2 pandemic has added new urgency to the study of viral mechanisms of infection. But while vaccines offer a measure of protection against this specific outbreak, a new era of pandemics has been predicted. In addition to this,…

Biological Physics · Physics 2022-10-25 Betony Adams , Ilya Sinayskiy , Rienk van Grondelle , Francesco Petruccione

Covid-19 infection, which spread to the whole world in December 2019 and is still active, caused more than 250 thousand deaths in the world today. Researches on this subject have been focused on analyzing the genetic structure of the virus,…

Machine Learning · Computer Science 2023-04-25 Selcuk Yazar

COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the understanding of the molecular mechanisms involved in…

SARS-CoV-2 started propagating worldwide in January 2020 and has now reached virtually all communities on the planet. This short review provides evidence of this spread and documents modelling efforts undertaken to understand and forecast…

Populations and Evolution · Quantitative Biology 2025-05-26 Julien Arino