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Related papers: Estimating Risk-Adjusted Hospital Performance

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Machine learning systems show significant promise for forecasting patient adverse events via risk scores. However, these risk scores implicitly encode assumptions about future interventions that the patient is likely to receive, based on…

Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress…

Machine Learning · Computer Science 2018-03-05 Dev Goyal , Zeeshan Syed , Jenna Wiens

Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful…

Methodology · Statistics 2021-04-26 Kristen B. Hunter , Mark E. Glickman , Luis F. Campos

Electronic Medical Records (EMR) are a rich source of patient information, including measurements reflecting physiologic signs and administered therapies. Identifying which variables are useful in predicting clinical outcomes can be…

Machine Learning · Statistics 2019-04-03 Eugene Laksana , Melissa Aczon , Long Ho , Cameron Carlin , David Ledbetter , Randall Wetzel

We consider the problem of estimating the average treatment effect (ATE) in a semi-supervised learning setting, where a very small proportion of the entire set of observations are labeled with the true outcome but features predictive of the…

Methodology · Statistics 2020-10-27 David Cheng , Ashwin Ananthakrishnan , Tianxi Cai

Continuous biomarkers are common for disease screening and diagnosis. To reach a dichotomous clinical decision, a threshold would be imposed to distinguish subjects with disease from non-diseased individuals. Among various performance…

Methodology · Statistics 2021-04-21 Ziyi Li , Yijuan Huang , Dattatraya Patil , Martin G. Sanda

For patients undergoing systemic cancer therapy, the time between clinic visits is full of uncertainties and risks of unmonitored side effects. To bridge this gap in care, we developed and prospectively trialed a multi-modal AI framework…

Electronic health records (EHRs) provide a powerful basis for predicting the onset of health outcomes. Yet EHRs primarily capture in-clinic events and miss aspects of daily behavior and lifestyle containing rich health information. Consumer…

We offer a pragmatic model to operationalize responsible, secure, and sustainable healthcare AI, aligning world-class technical excellence with organizational readiness. The framework includes five key pillars - Leadership & Strategy, MLOps…

Computers and Society · Computer Science 2025-10-21 Jimmy Joseph

Most statistical process control programmes in healthcare focus on surveillance of outcomes at the final stage of a procedure, such as mortality or failure rates. Such an approach ignores the multi-stage nature of these procedures, in which…

Methodology · Statistics 2020-06-29 Doaa Ayad , Nokuthaba Sibanda

Propensity score weighting approaches have been widely implemented in clinical research to estimate the effects of a treatment or exposure while mitigating the risk of confounding in the absence of random assignment. In practice, when…

Methodology · Statistics 2026-04-17 Emma K. Mackay , Amol A. Verma , Fahad Razak , Surain B. Roberts

Cancer treatment outcomes are influenced not only by clinical and demographic factors but also by the collaboration of healthcare teams. However, prior work has largely overlooked the potential role of human collaboration in shaping patient…

Social and Information Networks · Computer Science 2025-12-04 Hsiao-Ying Lu , Kwan-Liu Ma

Hospitals lack automated systems to harness the growing volume of heterogeneous clinical and operational data to effectively forecast critical events. Early identification of patients at risk for deterioration is essential not only for…

There is tremendous interest in precision medicine as a means to improve patient outcomes by tailoring treatment to individual characteristics. An individualized treatment rule formalizes precision medicine as a map from patient information…

Machine Learning · Statistics 2020-05-28 Daniel J. Luckett , Eric B. Laber , Michael R. Kosorok

Hospital readmission prediction is a study to learn models from historical medical data to predict probability of a patient returning to hospital in a certain period, 30 or 90 days, after the discharge. The motivation is to help health…

Machine Learning · Computer Science 2021-06-17 Shuwen Wang , Xingquan Zhu

The receiver operating characteristic (ROC) curve is a very useful tool for analyzing the diagnostic/classification power of instruments/classification schemes as long as a binary-scale gold standard is available. When the gold standard is…

Methodology · Statistics 2011-05-10 Zhanfeng Wang , Yuan-chin Ivan Chang

Randomized Controlled Trials (RCT) are the current gold standards to empirically measure the effect of a new drug. However, they may be of limited size and resorting to complementary non-randomized data, referred to as observational, is…

Methodology · Statistics 2025-06-11 Ahmed Boughdiri , Julie Josse , Erwan Scornet

Measuring the effect of patient safety improvement efforts is needed to determine their value but is difficult due to the inherent complexities of hospital operations. In this paper, we show by case study how interrupted time series design…

Applications · Statistics 2018-06-28 Diego A. Martinez , Mehdi Jalalpour , David T. Efron , Scott R. Levin

In high-stakes risk prediction, quantifying uncertainty through interval-valued predictions is essential for reliable decision-making. However, standard evaluation tools like the receiver operating characteristic (ROC) curve and the area…

Machine Learning · Computer Science 2026-02-05 Yuqi Li , Matthew M. Engelhard

The paper investigates the escalating concerns surrounding the surge in diabetes cases, exacerbated by the COVID-19 pandemic, and the subsequent strain on medical resources. The research aims to construct a predictive model quantifying…

Applications · Statistics 2025-02-04 Jorden Lam , Kunpeng Xu
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