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In the last several years deep learning based approaches have come to dominate many areas of computer vision, and image denoising is no exception. Neural networks can learn by example to map noisy images to clean images. However, access to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Jason Lequyer , Reuben Philip , Amit Sharma , Laurence Pelletier

The field of image denoising is currently dominated by discriminative deep learning methods that are trained on pairs of noisy input and clean target images. Recently it has been shown that such methods can also be trained without clean…

Computer Vision and Pattern Recognition · Computer Science 2019-04-08 Alexander Krull , Tim-Oliver Buchholz , Florian Jug

Medical image denoising is considered among the most challenging vision tasks. Despite the real-world implications, existing denoising methods have notable drawbacks as they often generate visual artifacts when applied to heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 S M A Sharif , Rizwan Ali Naqvi , Woong-Kee Loh

Current self-supervised denoising techniques achieve impressive results, yet their real-world application is frequently constrained by substantial computational and memory demands, necessitating a compromise between inference speed and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Tomáš Chobola , Julia A. Schnabel , Tingying Peng

Image enhancement approaches often assume that the noise is signal independent, and approximate the degradation model as zero-mean additive Gaussian. However, this assumption does not hold for biomedical imaging systems where sensor-based…

Image and Video Processing · Electrical Eng. & Systems 2023-04-10 Calvin-Khang Ta , Abhishek Aich , Akash Gupta , Amit K. Roy-Chowdhury

In the last few years, with the rapid development of deep learning technologies, supervised methods based on convolutional neural networks have greatly enhanced the performance of medical image denoising. However, these methods require…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Langrui Zhou , Ziteng Zhou , Xinyu Huang , Huiru Wang , Xiangyu Zhang , Guang Li

Image denoising is of great importance for medical imaging system, since it can improve image quality for disease diagnosis and downstream image analyses. In a variety of applications, dynamic imaging techniques are utilized to capture the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Junshen Xu , Elfar Adalsteinsson

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

Noise is an important issue for radiographic and tomographic imaging techniques. It becomes particularly critical in applications where additional constraints force a strong reduction of the Signal-to-Noise Ratio (SNR) per image. These…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Yaroslav Zharov , Evelina Ametova , Rebecca Spiecker , Tilo Baumbach , Genoveva Burca , Vincent Heuveline

Recently, there has been extensive research interest in training deep networks to denoise images without clean reference. However, the representative approaches such as Noise2Noise, Noise2Void, Stein's unbiased risk estimator (SURE), etc.…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Kwanyoung Kim , Jong Chul Ye

Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

Recovering a high-quality image from noisy indirect measurements is an important problem with many applications. For such inverse problems, supervised deep convolutional neural network (CNN)-based denoising methods have shown strong…

Image and Video Processing · Electrical Eng. & Systems 2020-09-16 Allard A. Hendriksen , Daniel M. Pelt , K. Joost Batenburg

Deep learning approaches in image processing predominantly resort to supervised learning. A majority of methods for image denoising are no exception to this rule and hence demand pairs of noisy and corresponding clean images. Only recently…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Priyatham Kattakinda , A. N. Rajagopalan

Real noisy-clean pairs on a large scale are costly and difficult to obtain. Meanwhile, supervised denoisers trained on synthetic data perform poorly in practice. Self-supervised denoisers, which learn only from single noisy images, solve…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Zejin Wang , Jiazheng Liu , Guoqing Li , Hua Han

Microscopy image analysis often requires the segmentation of objects, but training data for this task is typically scarce and hard to obtain. Here we propose DenoiSeg, a new method that can be trained end-to-end on only a few annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-06-12 Tim-Oliver Buchholz , Mangal Prakash , Alexander Krull , Florian Jug

Image denoising is the first step in many biomedical image analysis pipelines and Deep Learning (DL) based methods are currently best performing. A new category of DL methods such as Noise2Void or Noise2Self can be used fully unsupervised,…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Mangal Prakash , Manan Lalit , Pavel Tomancak , Alexander Krull , Florian Jug

Image noise modeling is a long-standing problem with many applications in computer vision. Early attempts that propose simple models, such as signal-independent additive white Gaussian noise or the heteroscedastic Gaussian noise model…

Image and Video Processing · Electrical Eng. & Systems 2022-06-03 Ali Maleky , Shayan Kousha , Michael S. Brown , Marcus A. Brubaker

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

Image denoising is a fundamental task in computer vision, particularly in medical ultrasound (US) imaging, where speckle noise significantly degrades image quality. Although recent advancements in deep neural networks have led to…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Xuesong Li , Nassir Navab , Zhongliang Jiang

In recent years, neural network based image denoising approaches have revolutionized the analysis of biomedical microscopy data. Self-supervised methods, such as Noise2Void (N2V), are applicable to virtually all noisy datasets, even without…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Eva Höck , Tim-Oliver Buchholz , Anselm Brachmann , Florian Jug , Alexander Freytag
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