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A phase field approach is proposed to model the chemotaxis of Dictyostelium discoideum. In this framework, motion is controlled by active forces as determined by the Meinhardt model of chemical dynamics which is used to simulate directional…

Biological Physics · Physics 2023-03-01 Yunsong Zhang , Herbert Levine , Yanxiang Zhao

Collective migration of eukaryotic cells is often guided by chemotaxis, and is critical in several biological processes, such as cancer metastasis, wound healing, and embryogenesis. Understanding collective chemotaxis has challenged…

Biological Physics · Physics 2024-08-12 Aditya Paspunurwar , Adrian Moure , Hector Gomez

We introduce a generic, purely mechanical model for environment sensitive motion of mammalian cells that is applicable to chemotaxis, haptotaxis, and durotaxis as modes of motility. It is able to theoretically explain all relevant…

Cell Behavior · Quantitative Biology 2016-05-09 Patrick Bitter , Kristof Leon Beck , Peter Lenz

We study a chemotaxis-growth system with nonlinear local and nonlocal reactions and gradient-dependent damping. Under suitable conditions on the system parameters and spatial dimension, we prove that solutions exist globally in time and…

Analysis of PDEs · Mathematics 2025-07-29 Tongxing Li , Silvia Frassu , Giuseppe Viglialoro

Run-and-tumble particles (RTPs) have emerged as a paradigmatic example for studying nonequilibrium phenomena in statistical mechanics. The invariant measure of a wide class of RTPs subjected to a potential possesses a density that is…

Statistical Mechanics · Physics 2025-11-24 Leo Hahn

We model, analyze, and simulate a novel run-and-tumble model with autochemotaxis, biologically inspired by the phytoplankton Heterosigma akashiwo. Developing a fundamental understanding of planktonic movements and interactions through…

Dynamical Systems · Mathematics 2021-02-04 Nicholas J. Russell , Louis F. Rossi

Chemotaxis plays a crucial role in a variety of processes in biology and ecology. Quite often it acts to improve efficiency of biological reactions. One example is the immune system signalling, where infected tissues release chemokines…

Analysis of PDEs · Mathematics 2020-04-15 Alexander Kiselev , Fedor Nazarov , Lenya Ryzhik , Yao Yao

We consider model of a complex particle that consists of a rigid shell and a nucleus with spatial asymmetric interaction. The particle's dynamics with the nucleus driven by a periodic excitation is considered. It is shown that…

Chaotic Dynamics · Physics 2007-05-23 Sergey Denisov

We develop a multiscale hybrid scheme for simulations of soft condensed matter systems, which allows one to treat the system at the particle level in selected regions of space, and at the continuum level elsewhere. It is derived…

Soft Condensed Matter · Physics 2015-06-17 Shuanhu Qi , Hans Behringer , Friederike Schmid

We develop the hydrodynamic theory of dry, polar ordered, active matter (``flocking") with autochemotaxis; i.e., self-propelled entities moving in the same direction, each emitting a substance which attracts the others (e.g., ants). We find…

Soft Condensed Matter · Physics 2024-01-22 Maxx Miller , John Toner

Atoms in spatially dependent light fields are attracted to local intensity maxima or minima depending on the sign of the frequency difference between the light and the atomic resonance. For light fields confined in open high-Q optical…

Quantum Physics · Physics 2019-08-05 Arthur Jungkind , Wolfgang Niedenzu , Helmut Ritsch

In this work we numerically study the diffusive limit of run & tumble kinetic models for cell motion due to chemotaxis by means of asymptotic preserving schemes. It is well-known that the diffusive limit of these models leads to the…

Numerical Analysis · Mathematics 2011-10-18 Jose A. Carrillo , Bokai Yan

In micro-swimmer suspensions locomotion necessarily generates fluid motion, and it is known that such flows can lead to collective behavior from unbiased swimming. We examine the complementary problem of how chemotaxis is affected by…

Biological Physics · Physics 2012-10-23 Enkeleida Lushi , Raymond E. Goldstein , Michael J. Shelley

Inspired by the Turing mechanism for pattern formation, we propose a simple self-propelled particle model with short-ranged alignment and anti-alignment at larger distances. It is able to produce orientationally ordered states, periodic…

Soft Condensed Matter · Physics 2016-05-02 Robert Grossmann , Pawel Romanczuk , Markus Bär , Lutz Schimansky-Geier

{\sl Escherichia coli} ({\sl E. coli}) bacteria govern their trajectories by switching between running and tumbling modes as a function of the nutrient concentration they experienced in the past. At short time one observes a drift of the…

Statistical Mechanics · Physics 2011-12-08 Sakuntala Chatterjee , Rava Azeredo da Silveira , Yariv Kafri

Recently, we proposed a self-propelled particle model with competing alignment interactions: nearby particles tend to align their velocities whereas they anti-align their direction of motion with particles which are further away [R.…

Soft Condensed Matter · Physics 2016-05-02 Robert Großmann , Pawel Romanczuk , Markus Bär , Lutz Schimansky-Geier

A thermodynamically consistent particle-based model for fluid dynamics with continuous velocities and a non-ideal equation of state is presented. Excluded volume interactions are modeled by means of biased stochastic multiparticle…

Soft Condensed Matter · Physics 2009-11-11 Thomas Ihle , Erkan Tuzel , Daniel M. Kroll

Run-and-tumble is a basic model of persistent motion and a motility strategy widespread in micro-organisms and individual cells. In many natural settings, movement occurs in the presence of confinement. While accumulation at the surface has…

Soft Condensed Matter · Physics 2024-04-12 T. Pietrangeli , C. Ybert , C. Cottin-Bizonne , F. Detcheverry

Chemotaxis is the response of a particle to a gradient in the chemical composition of the environment. While it was originally observed for biological organisms, it is of great interest in the context of synthetic active particles such as…

Soft Condensed Matter · Physics 2017-05-02 Laurens Deprez , Pierre de Buyl

Chemotaxis is typically modeled in the context of cellular motion towards a static, exogenous source of chemoattractant. Here, we propose a time-dependent mechanism of chemotaxis in which a self-propelled particle ({\it e.g.}, a cell)…

Cell Behavior · Quantitative Biology 2026-05-12 Sarah A. Nowak , Buddhapriya Chakrabarti , Tom Chou , Ajay Gopinathan
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