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Alzheimer's disease (AD) is a neurodegenerative disorder that affects more than seven million people in the United States alone. AD currently has no cure, but there are ways to potentially slow its progression if caught early enough. In…
Structural MRI and PET imaging play an important role in the diagnosis of Alzheimer's disease (AD), showing the morphological changes and glucose metabolism changes in the brain respectively. The manifestations in the brain image of some…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…
Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…
Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…
Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…
Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the accumulation of amyloid-beta (A$\beta$) and phosphorylated tau (p-tau) proteins, leading to cognitive decline measured by the Alzheimer's Disease…
Increasing effort in brain image analysis has been dedicated to early diagnosis of Alzheimer's disease (AD) based on neuroimaging data. Most existing studies have been focusing on binary classification problems, e.g., distinguishing AD…
In the last decade, computer-aided early diagnostics of Alzheimer's Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research. Some recent studies have shown promising results in the AD…
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…
Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…
Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…
Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…
Nowadays, a lot of scientific efforts are concentrated on the diagnosis of Alzheimer's Disease (AD) applying deep learning methods to neuroimaging data. Even for 2017, there were published more than a hundred papers dedicated to AD…
This work validates the generalizability of MRI-based classification of Alzheimer's disease (AD) patients and controls (CN) to an external data set and to the task of prediction of conversion to AD in individuals with mild cognitive…
Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…
Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…
Alzheimer's disease is a progressive neurological disorder characterized by cognitive impairment and memory loss. With the increasing aging population, the incidence of AD is continuously rising, making early diagnosis and intervention an…
Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that predominantly affects the elderly population and currently has no cure. Magnetic Resonance Imaging (MRI), as a non-invasive imaging technique, is essential for the…