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Biological systems reach organizational complexity that far exceeds the complexity of any known inanimate objects. Biological entities undoubtedly obey the laws of quantum physics and statistical mechanics. However, is modern physics…

Other Quantitative Biology · Quantitative Biology 2018-02-26 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

Generative diffusion models have achieved spectacular performance in many areas of machine learning and generative modeling. While the fundamental ideas behind these models come from non-equilibrium physics, variational inference and…

Machine Learning · Statistics 2024-06-21 Luca Ambrogioni

The approach of nonequilibrium evolution thermodynamics earlier offered is developed. It helps to describe the processes of defect formation within the adiabatic approximation. The basic equations system depends on the initial defects…

Materials Science · Physics 2015-10-23 A. V. Khomenko , D. S. Troshchenko , L. S. Metlov

For studying the thermodynamic properties of systems using statistical mechanics we propose an ensemble that lies in between the familiar canonical and microcanonical ensembles. From a comparative study of these ensembles we conclude that…

Statistical Mechanics · Physics 2007-05-23 R. P. Venkataraman

Understanding the spatial organisation of the genome in the cell nucleus is one of the current grand challenges in biophysics. Certain biochemical -- or epigenetic -- marks that are deposited along the genome are thought to play an…

Soft Condensed Matter · Physics 2020-01-08 Davide Michieletto , Davide Colí , Davide Marenduzzo , Enzo Orlandini

The possibility that evolutionary forces -- together with a few fundamental factors such as thermodynamic constraints, specific computational features enabling information processing, and ecological processes -- might constrain the logic of…

Biological Physics · Physics 2025-12-30 Manlio De Domenico

We demonstrate the equilibration of isolated macroscopic quantum systems, prepared in non-equilibrium mixed states with significant population of many energy levels, and observed by instruments with a reasonably bound working range compared…

Statistical Mechanics · Physics 2009-11-13 Peter Reimann

An alternative approach - nonequilibrium evolution thermodynamics, is compared with classical Landau approach. A statistical justification of the approach is carried out with help of probability distribution function on an example of a…

Statistical Mechanics · Physics 2010-08-13 Leonid S. Metlov

In recent times whole-genome gene expression analysis has turned out to be a highly important tool to study the coordinated function of a very large number of genes within their corresponding cellular environment, especially in relation to…

Genomics · Quantitative Biology 2009-09-21 Enrique Hernandez-Lemus

This position paper argues that next-generation non-equilibrium-inspired generative models will provide the essential foundation for better modeling real-world complex dynamical systems. While many classical generative algorithms draw…

Computational Engineering, Finance, and Science · Computer Science 2025-05-27 Jiazhen Liu , Ruikun Li , Huandong Wang , Zihan Yu , Chang Liu , Jingtao Ding , Yong Li

Gibbs and Boltzmann definitions of temperature agree only in the macroscopic limit. The ambiguity in identifying the equilibrium temperature of a finite sized `small' system exchanging energy with a bath is usually understood as a…

Biological Physics · Physics 2015-03-09 Purushottam D. Dixit

We constructed a model that evolved from a non-equilibrium state to an equilibrium state. The model only needs two basic coefficients, including self-similar coefficients and non-equilibrium coefficients. The coefficients of the model can…

Statistical Mechanics · Physics 2020-11-24 Zhifu Huang , Yuqing Wang

We show how statistical thermodynamics can be formulated in situations in which thermodynamics applies, while equilibrium statistical mechanics does not. A typical case is, in the words of Landau and Lifshitz, that of partial (or…

Statistical Mechanics · Physics 2013-04-16 A. Carati , A. Maiocchi , L. Galgani

Statistical thermodynamics delivers the probability distribution of the equilibrium state of matter through the constrained maximization of a special functional, entropy. Its elegance and enormous success have led to numerous attempts to…

Statistical Mechanics · Physics 2023-06-22 Themis Matsoukas

Stochastic differential equations have proved to be a valuable governing framework for many real-world systems which exhibit ``noise'' or randomness in their evolution. One quality of interest in such systems is the shape of their…

Dynamical Systems · Mathematics 2025-02-04 David Sabin-Miller , Daniel M. Abrams

Statistical physics and dynamical systems theory are key tools to study high-impact geophysical events such as temperature extremes, cyclones, thunderstorms, geomagnetic storms and many more. Despite the intrinsic differences between these…

The steady state shock formation in processes like nonconserving asymmetric simple exclusion processes in varied situations is shown to be a nonequilibrium critical phenomenon. The diverging length scales and the quantitative description of…

Statistical Mechanics · Physics 2009-11-10 Sutapa Mukherji , Somendra M. Bhattacharjee

Diverse equilibrium systems with heterogeneous interactions lie at the edge of stability. Such marginally stable states are dynamically selected as the most abundant ones or as those with the largest basins of attraction. On the other hand,…

Disordered Systems and Neural Networks · Physics 2025-10-10 Carles Martorell , Rubén Calvo , Alessia Annibale , Miguel A. Muñoz

We address the problem of the dynamical foundation of non-canonical equilibrium. We consider, as a source of divergence from ordinary statistical mechanics, the breakdown of the condition of time scale separation between microscopic and…

Statistical Mechanics · Physics 2009-10-31 M. Annunziato , P. Grigolini , B. J. West

Non-equilibrium dynamics are present in many aspects of our lives, ranging from microscopic physical systems to the functioning of the brain. What characterizes stochastic models of non-equilibrium processes is the breaking of the…

Statistical Mechanics · Physics 2025-01-27 Sergei Shmakov , Peter B. Littlewood