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Multi-label classification, which involves assigning multiple labels to a single input, has emerged as a key area in both research and industry due to its wide-ranging applications. Designing effective loss functions is crucial for…

Machine Learning · Computer Science 2025-01-06 Alexandre Audibert , Aurélien Gauffre , Massih-Reza Amini

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

Machine Learning · Statistics 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

The mainstream of research in genetics, epigenetics and imaging data analysis focuses on statistical association or exploring statistical dependence between variables. Despite their significant progresses in genetic research, understanding…

Genomics · Quantitative Biology 2018-05-14 Rong Jiao , Nan Lin , Zixin Hu , David A Bennett , Li Jin , Momiao Xiong

Identifying causal relations is crucial for a variety of downstream tasks. In additional to observational data, background knowledge (BK), which could be attained from human expertise or experiments, is usually introduced for uncovering…

Artificial Intelligence · Computer Science 2024-07-23 Tian-Zuo Wang , Lue Tao , Zhi-Hua Zhou

Bidirectional causal relationships arising from mutual interactions between variables are commonly observed within biomedical, econometrical, and social science contexts. When such relationships are further complicated by unobserved…

Methodology · Statistics 2026-01-27 Yafang Deng , Kang Shuai , Shanshan Luo

Causal additive models provide a tractable yet expressive framework for causal discovery in the presence of hidden variables. When unobserved backdoor or causal paths exist between two variables, their causal relationship is often…

Machine Learning · Computer Science 2026-05-25 Thong Pham , Takashi Nicholas Maeda , Shohei Shimizu

This paper deals with the problem of evaluating the causal effect using observational data in the presence of an unobserved exposure/ outcome variable, when cause-effect relationships between variables can be described as a directed acyclic…

Methodology · Statistics 2012-06-18 Manabu Kuroki , Zhihong Cai

Graphical causal models are an important tool for knowledge discovery because they can represent both the causal relations between variables and the multivariate probability distributions over the data. Once learned, causal graphs can be…

Artificial Intelligence · Computer Science 2017-04-11 Andrew J Sedgewick , Joseph D. Ramsey , Peter Spirtes , Clark Glymour , Panayiotis V. Benos

Finding a causal model for a set of classical variables is now a well-established task---but what about the quantum equivalent? Even the notion of a quantum causal model is controversial. Here, we present a causal discovery algorithm for…

Quantum Physics · Physics 2018-04-20 Christina Giarmatzi , Fabio Costa

Machine learning approaches to multi-label document classification have to date largely relied on discriminative modeling techniques such as support vector machines. A drawback of these approaches is that performance rapidly drops off as…

Machine Learning · Statistics 2011-11-11 Timothy N. Rubin , America Chambers , Padhraic Smyth , Mark Steyvers

Unveil, model, and comprehend the causal mechanisms underpinning natural phenomena stand as fundamental endeavors across myriad scientific disciplines. Meanwhile, new knowledge emerges when discovering causal relationships from data.…

Machine Learning · Computer Science 2023-12-13 Jiaxuan Liang , Jun Wang , Guoxian Yu , Shuyin Xia , Guoyin Wang

Recent years have seen rapid progress at the intersection between causality and machine learning. Motivated by scientific applications involving high-dimensional data, in particular in biomedicine, we propose a deep neural architecture for…

Machine Learning · Computer Science 2022-12-12 Kai Lagemann , Christian Lagemann , Bernd Taschler , Sach Mukherjee

Multi-label classification is an important learning problem with many applications. In this work, we propose a principled similarity-based approach for multi-label learning called SML. We also introduce a similarity-based approach for…

Machine Learning · Statistics 2017-10-31 Ryan A. Rossi , Nesreen K. Ahmed , Hoda Eldardiry , Rong Zhou

This paper proposes two methods for causal additive models with unobserved variables (CAM-UV). CAM-UV assumes that the causal functions take the form of generalized additive models and that latent confounders are present. First, we propose…

Machine Learning · Computer Science 2024-01-19 Takashi Nicholas Maeda , Shohei Shimizu

Identifying variables responsible for changes to a biological system enables applications in drug target discovery and cell engineering. Given a pair of observational and interventional datasets, the goal is to isolate the subset of…

Machine Learning · Computer Science 2025-06-02 Menghua Wu , Umesh Padia , Sean H. Murphy , Regina Barzilay , Tommi Jaakkola

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

Artificial Intelligence · Computer Science 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Competitive methods for multi-label classification typically invest in learning labels together. To do so in a beneficial way, analysis of label dependence is often seen as a fundamental step, separate and prior to constructing a…

Machine Learning · Statistics 2017-07-19 Jesse Read , Jaakko Hollmén

We propose a method to classify the causal relationship between two discrete variables given only the joint distribution of the variables, acknowledging that the method is subject to an inherent baseline error. We assume that the causal…

Machine Learning · Statistics 2016-11-07 Krzysztof Chalupka , Frederick Eberhardt , Pietro Perona

This paper attempts multi-label classification by extending the idea of independent binary classification models for each output label, and exploring how the inherent correlation between output labels can be used to improve predictions.…

Machine Learning · Computer Science 2015-11-26 Amit Garg , Jonathan Noyola , Romil Verma , Ashutosh Saxena , Aditya Jami
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