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Cell alignment often forms nematic order, which can lead to anomalous collective cell flow due to the so-called active force. Although it is appreciated that cell migration is driven by traction force, a quantitative evaluation of the…

Soft Condensed Matter · Physics 2024-02-27 Masahito Uwamichi , He Li , Zihui Zhao , Yisong Yao , Hideo Higuchi , Kyogo Kawaguchi , Masaki Sano

Cellular self-assembly and organization are fundamental steps for the development of biological tissues. In this paper, within the framework of a cellular automata model, we address how an ordered tissue pattern spontaneously emerges from a…

Biological Physics · Physics 2019-10-24 Debangana Mukhopadhyay , Rumi De

Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important in single cells, especially in large oocytes…

We quantitatively study the transport of E. coli near the walls of confined microfluidic channels, and in more detail along the edges formed by the interception of two perpendicular walls. Our experiments establish the connection between…

Molecular motors interacting with cytoskeletal filaments undergo peculiar random walks consisting of alternating sequences of directed movements along the filaments and diffusive motion in the surrounding solution. An ensemble of motors is…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

We theoretically study the transport properties of self-propelled particles on complex structures, such as motor proteins on filament networks. A general master equation formalism is developed to investigate the persistent motion of…

Soft Condensed Matter · Physics 2014-09-19 M. Reza Shaebani , Zeinab Sadjadi , Igor M. Sokolov , Heiko Rieger , Ludger Santen

Increasing evidence suggests that cities are complex systems, with structural and dynamical features responsible for a broad spectrum of emerging phenomena. Here we use a unique data set of human flows and couple it with information on the…

Physics and Society · Physics 2021-01-22 Riccardo Gallotti , Giulia Bertagnolli , Manlio De Domenico

The organization of cells within tissues plays a vital role in various biological processes, including development and morphogenesis. As a result, understanding how cells self-organize in tissues has been an active area of research. In our…

Soft Condensed Matter · Physics 2023-10-09 Kanaya Malakar , Rafael I. Rubenstein , Dapeng Bi , Bulbul Chakraborty

The twisting and writhing of a cell body and associated mechanical stresses is an underappreciated constraint on microbial self-propulsion. Multi-flagellated bacteria can even buckle and writhe under their own activity as they swim through…

Soft Condensed Matter · Physics 2023-09-25 Wilson Lough , Douglas B. Weibel , Saverio E. Spagnolie

In densely-packed two-dimensional systems of growing cells, such as rod-shaped bacteria, a number of experimental and numerical studies report distinct patterns of nematic orientational order in the presence of confinement. So far, these…

Soft Condensed Matter · Physics 2025-06-13 Lukas Hupe , Jonas Isensee , Ramin Golestanian , Philip Bittihn

We present a generic model of cell motility generated by acto-myosin contraction of the cell cortex. We identify analytically dynamical instabilities of the cortex and show that they trigger spontaneous cortical flows which in turn can…

Cell Behavior · Quantitative Biology 2015-05-20 R. J. Hawkins , R. Poincloux , O. Bénichou , M. Piel , P. Chavrier , R. Voituriez

Complex networks are characterized by latent geometries induced by their topology or by the dynamics on the top of them. In the latter case, different network-driven processes induce distinct geometric features that can be captured by…

Physics and Society · Physics 2021-04-07 Giulia Bertagnolli , Manlio De Domenico

Non-motile elongated bacteria confined in two-dimensional open micro-channels can exhibit collective motion and form dense monolayers with nematic order if the cells proliferate, i.e., grow and divide. Using soft molecular dynamics…

Soft Condensed Matter · Physics 2013-07-25 Sirio Orozco-Fuentes , Denis Boyer

Many-body interactions in systems of active matter can cause particles to move collectively and self-organize into dynamic structures with long-range order. In cells, the self-assembly of cytoskeletal filaments is critical for cellular…

Soft Condensed Matter · Physics 2020-05-26 Jeffrey M. Moore , Matthew A. Glaser , Meredith D. Betterton

Population heterogeneity is ubiquitous among active living systems, but little is known about its role in determining their spatial organization and large-scale dynamics. Combining evidence from synthetic active fluids assembled from…

Soft Condensed Matter · Physics 2023-11-27 Samadarshi Maity , Alexandre Morin

A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…

Biological Physics · Physics 2022-02-03 H. Chelly , A. Jahangiri , M. Mireux , J. Étienne , D. K. Dysthe , C. Verdier , P. Recho

Motivated by recent experiments demonstrating that motile algae get trapped in draining foams, we study the trajectories of microorganisms confined in model foam channels (section of a Plateau border). We track single Chlamydomonas…

Biological Physics · Physics 2021-04-19 Albane Théry , Yuxuan Wang , Mariia Dvoriashyna , Christophe Eloy , Florence Elias , Eric Lauga

The colonisation of a soft passive material by motile cells such as bacteria is common in biology. The resulting colonies of the invading cells are often observed to exhibit intricate patterns whose morphology and dynamics can depend on a…

Soft Condensed Matter · Physics 2021-01-12 Mohammad Imaran , Mandar Inamdar , Ranganathan Prabhakar , Raghunath Chelakkot

We consider non-linear evolution equations arising from mean-field limits of particle systems on discrete spaces. We investigate a notion of curvature bounds for these dynamics based on convexity of the free energy along interpolations in a…

Probability · Mathematics 2020-06-04 Matthias Erbar , Max Fathi , André Schlichting

Gyrotactic algae are bottom heavy, motile cells whose swimming direction is determined by a balance between a buoyancy torque directing them upwards and fluid velocity gradients. Gyrotaxis has, in recent years, become a paradigmatic model…

Chaotic Dynamics · Physics 2019-03-25 Massimo Cencini , Guido Boffetta , Matteo Borgnino , Filippo De Lillo