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We introduce a statistical physics inspired supervised machine learning algorithm for classification and regression problems. The method is based on the invariances or stability of predicted results when known data is represented as…

Machine Learning · Statistics 2018-11-19 Patrick Chao , Tahereh Mazaheri , Bo Sun , Nicholas B. Weingartner , Zohar Nussinov

Selection bias arises when the probability that an observation enters a dataset depends on variables related to the quantities of interest, leading to systematic distortions in estimation and uncertainty quantification. For example, in…

Modeling transformations between arbitrary data distributions is a fundamental scientific challenge, arising in applications like drug discovery and evolutionary simulation. While flow matching offers a natural framework for this task, its…

Machine Learning · Computer Science 2025-10-09 Shiye Su , Yuhui Zhang , Linqi Zhou , Rajesh Ranganath , Serena Yeung-Levy

The four-dimensional variational data assimilation methodology for assimilating noisy observations into a deterministic model has been the workhorse of forecasting centers for over three decades. While this method provides a computationally…

Optimization and Control · Mathematics 2023-07-19 Shady E Ahmed , Omer San , Sivaramakrishnan Lakshmivarahan , John M Lewis

In this work, we study how to use sampling to speed up mechanisms for answering adaptive queries into datasets without reducing the accuracy of those mechanisms. This is important to do when both the datasets and the number of queries asked…

Machine Learning · Computer Science 2020-01-03 Benjamin Fish , Lev Reyzin , Benjamin I. P. Rubinstein

The concept of mathematical modeling is widespread across almost all of the fields of contemporary science and engineering. Because of the existing necessity of predictions the behavior of natural phenomena, the researchers develop more and…

Machine Learning · Computer Science 2019-04-10 Marcin Sendera

Approximate Bayesian Computation is widely used in systems biology for inferring parameters in stochastic gene regulatory network models. Its performance hinges critically on the ability to summarize high-dimensional system responses such…

Machine Learning · Statistics 2021-04-13 Mattias Åkesson , Prashant Singh , Fredrik Wrede , Andreas Hellander

Frequency estimation from measurements corrupted by noise is a fundamental challenge across numerous engineering and scientific fields. Among the pivotal factors shaping the resolution capacity of any frequency estimation technique are…

Signal Processing · Electrical Eng. & Systems 2024-09-23 Sampath Kumar Dondapati , Omkar Nitsure , Satish Mulleti

Active statistical inference is a new method for inference with AI-assisted data collection. Given a budget on the number of labeled data points that can be collected and assuming access to an AI predictive model, the basic idea is to…

Machine Learning · Statistics 2025-11-13 Puheng Li , Tijana Zrnic , Emmanuel Candès

Ensuring that analyses performed on a dataset are representative of the entire population is one of the central problems in statistics. Most classical techniques assume that the dataset is independent of the analyst's query and break down…

Machine Learning · Computer Science 2024-09-25 Guy Blanc

The motivation for this paper stems from the desire to develop an adaptive sampling method for solving constrained optimization problems in which the objective function is stochastic and the constraints are deterministic. The method…

Optimization and Control · Mathematics 2021-01-01 Yuchen Xie , Raghu Bollapragada , Richard Byrd , Jorge Nocedal

For the Research Topic Data Assimilation and Control: Theory and Applications in Life Sciences we first review the formulation of statistical data assimilation (SDA) and discuss algorithms for exploring variational approximations to the…

Neurons and Cognition · Quantitative Biology 2018-09-17 Anna Miller , Dawei Li , Jason Platt , Arij Daou , Daniel Margoliash , Henry Abarbanel

Data assimilation is a method that combines observations (that is, real world data) of a state of a system with model output for that system in order to improve the estimate of the state of the system and thereby the model output. The model…

Numerical Analysis · Mathematics 2020-05-18 Melina A. Freitag

Sampling is an important tool for estimating large, complex sums and integrals over high dimensional spaces. For instance, important sampling has been used as an alternative to exact methods for inference in belief networks. Ideally, we…

Artificial Intelligence · Computer Science 2013-01-18 Luis E. Ortiz , Leslie Pack Kaelbling

The statistical problem of parameter estimation in partially observed hypoelliptic diffusion processes is naturally occurring in many applications. However, due to the noise structure, where the noise components of the different coordinates…

Methodology · Statistics 2018-11-13 Susanne Ditlevsen , Adeline Samson

Modern applications require methods that are computationally feasible on large datasets but also preserve statistical efficiency. Frequently, these two concerns are seen as contradictory: approximation methods that enable computation are…

Methodology · Statistics 2021-06-11 Darren Homrighausen , Daniel J. McDonald

Researchers recently found out that sometimes language models achieve high accuracy on benchmark data set, but they can not generalize very well with even little changes to the original data set. This is sometimes due to data artifacts,…

Computation and Language · Computer Science 2024-01-26 Han Chen

The concept of biased data is well known and its practical applications range from social sciences and biology to economics and quality control. These observations arise when a sampling procedure chooses an observation with probability that…

Statistics Theory · Mathematics 2007-06-13 Sam Efromovich

Estimating the mixing density of a mixture distribution remains an interesting problem in statistics literature. Using a stochastic approximation method, Newton and Zhang (1999) introduced a fast recursive algorithm for estimating the…

Statistics Theory · Mathematics 2022-03-29 Nilabja Guha , Anindya Roy

We develop and analyze a method for stochastic simulation optimization based on Gaussian process models within a trust-region framework. We focus on settings where the variance of the objective function is large, making accurate estimation…

Optimization and Control · Mathematics 2026-03-10 Mickael Binois , Jeffrey Larson
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